RxRadio

A podcast for everything Pharmacy.

07/04/2024

Happy 4th everyone! 🇺🇸

05/14/2024

Combo brought to you by the Pyrls T2DM Pharmacotherapy chart.

05/12/2024

Happy Mother’s Day! 🌸

05/08/2024

In 1747, James Lind, a Scottish surgeon in the Royal Navy, conducted the first controlled clinical trial by dividing 12 sailors with scurvy into separate groups and testing the effect of various treatments. His study showed that citrus fruits could effectively treat scurvy.

05/08/2024

In 2017, the FOURIER trial showed that Evolocumab significantly reduces the risk of cardiovascular events by lowering LDL cholesterol levels beyond traditional treatments in patients with established cardiovascular disease.

05/06/2024

In 1998, Dr. Andrew Fire and Dr. Craig Mello published a groundbreaking paper in the journal Nature, describing their discovery of RNA interference where RNA molecules inhibit gene expression or translation by neutralizing targeted mRNA molecules.

05/05/2024

In the early 1980s, the first wearable insulin pump, called the AutoSyringe, was developed by American inventor and entrepreneur Dean Kamen. This was a significant advancement in diabetes management as it allowed for more accurate and consistent insulin delivery.

05/03/2024

British Surgeon Joseph Lister pioneered the use of carbolic acid (phenol) as an antiseptic, dramatically reducing surgical infection rates in the 1860s. This was a major breakthrough at a time when surgical infections were common and often fatal.

04/29/2024

In 1979, Judy Faulkner founded Epic Systems in a basement in Madison, Wisconsin, with a vision to revolutionize healthcare technology. She started the company with just $70,000 in startup capital, which she raised from friends and family.

04/28/2024

In the 1930s, Gerhard Domagk developed the first commercially significant antibiotic, a sulfonamide named Prontosil, when he was working for the German pharmaceutical company Bayer investigating the antibacterial properties of synthetic dyes.

04/20/2024

The VERTIS CV trial showed that Ertugliflozin not only helps manage blood sugar levels but also does not increase the risk of major adverse cardiovascular events in type 2 diabetes patients with established cardiovascular disease.

04/19/2024

How could they have possibly thought this was a good idea.

04/18/2024

In the 1950s, Lithium was accidentally discovered as a treatment for bipolar disorder by Australian psychiatrist John Cade, who identified its mood-stabilizing properties while conducting experiments to understand the role of uric acid in manic-depressive illness.

04/17/2024

The mortar and pestle have been essential tools since around 35,000 BC, used globally in ancient cultures for grinding seeds and nuts. Made from durable stone, these tools were fundamental in food preparation and medicinal practices long before modern conveniences.

04/16/2024

Interferon beta-1b, the first MS modifying drug, was introduced as Betaseron in 1993, before its counterpart, interferon beta-1a (Avonex), which arrived in 1996. The "a" and "b" distinguish their biochemical forms and their manufacturing processes, not a hierarchy or sequence.

04/15/2024

smh

04/14/2024

Pharmacist Wilbur Scoville introduced the Scoville Scale in 1912 to measure the pungency of chili peppers. This method assesses the concentration of capsaicinoids, like capsaicin, which create the heat sensation. It's still the standard for gauging pepper spiciness today.

04/13/2024

The CREDENCE trial showed that Canagliflozin significantly reduces the risk of kidney failure and cardiovascular events. It was the first dedicated renal outcome trial in patients with T2D and CKD, highlighting the benefits of canagliflozin beyond its glucose-lowering effects.

04/13/2024

In 2001, the first targeted cancer therapy, Imatinib (Gleevec), was approved by the FDA. It dramatically improved treatment for chronic myeloid leukemia by specifically targeting cancer cells, without harming healthy cells, significantly increasing survival rates.

04/13/2024

Whoops

04/12/2024

The first human insulin produced by recombinant DNA technology, Humulin, was marketed by Eli Lilly in 1981, revolutionizing diabetes management by providing a reliable and consistent synthetic source of insulin. Before Humulin, insulin was commonly derived from the pancreas of pigs and cows, which could cause allergic reactions and other issues in some patients.

04/11/2024

Accurate

04/11/2024

The first statin, lovastatin, was approved by the FDA in 1987, introduced by Merck. This innovation significantly advanced cholesterol management, reducing the risk of heart disease and stroke in millions globally.

04/11/2024

The PARADIGM-HF trial published in 2014 established Sacubitril/Valsartan as a game-changer in heart failure treatment, reducing the risk of death and hospitalization compared to standard treatment.

04/10/2024

Famed crime writer Agatha Christie was a pharmacy assistant during World War I where she gained a wealth of knowledge about medicines and poisons. This allowed her to create intriguing and believable stories involving poison, becoming a hallmark in the crime genre.

04/10/2024

In 1983, the first application of recombinant DNA technology led to the production of synthetic human insulin by Genentech. This innovation transformed diabetes management, offering a purer and more consistent insulin supply.

04/10/2024

Can relate ✒️

04/09/2024

Pepsi was invented by pharmacist Caleb Bradham in 1893 as "Brad's Drink," rebranded to Pepsi-Cola in 1898. The name is from pepsin and dyspepsia, aiming to offer a tasty beverage that helps in digestion. It doesn't contain pepsin, but it reflects a blend of flavor and function.

04/09/2024

Fun fact, Coca-Cola was first invented by a pharmacist named John Stith Pemberton in the year 1886.

04/08/2024

Staring at the sun without eye protection can lead to solar retinopathy, which is damage to the retina's fovea resulting in vision loss and eye pain. Treatment focuses on eye rest and symptom management using sunglasses for UV protection or pain relievers.

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How could they have possibly thought this was a good idea.

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Some facts on Entresto: ✰ Entresto (sacubitril/valsartan) is indicated for Heart Failure. ✰ Entresto is the only angiotensin receptor/neprilysin inhibitor (ARNI) available now. ✰ Entresto contains an ARB* and a neprilysin and its package insert recommends a washout period to reduce the potential for life-threatening angioedema.