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13/10/2024
Vaccine Administration Techniques-Drinking water.-Spray/nebulisation - at day of age. Birds in the housed environment.-E...
05/10/2024

Vaccine Administration Techniques

-Drinking water.
-Spray/nebulisation - at day of age. Birds in the housed environment.
-Eye drop.
-Transfixion and scarification (cutaneous route in the wing web or foot)
-Injection - intramuscular or subcutaneous.
-In-ovo administration

03/10/2024

Effective Use of Probiotics in Animal Nutrition: Key Insights for Industry Professionals

In animal nutrition, probiotics have proven to be valuable tools for enhancing gut health, preventing disease, and improving performance. However, it’s essential to recognize that not all probiotics are created equal, and their effectiveness can vary significantly depending on the strain and application. Below are some critical considerations for using probiotics effectively in your feed strategies.

1. Strain-Specific Efficacy Against Pathogens

Different probiotic strains exhibit unique behaviors in combating specific pathogens such as Salmonella and Clostridium. For example, certain strains of Lactobacillus and Bacillus have been shown to inhibit these bacteria through mechanisms such as lactic acid production and competitive exclusion . It’s vital to diagnose the primary challenge in your livestock and choose the appropriate probiotic strain tailored to address that specific issue. Not every probiotic will be equally effective against all pathogens.

2. Colony-Forming Units (CFU): The Critical Dosage

The concentration of probiotics in the feed, often expressed in colony-forming units (CFU), is crucial for ensuring their effectiveness. Research suggests that maintaining high CFU counts, typically around 10^9 CFU/kg of feed, is necessary to support optimal gut colonization and health benefits . Ensuring that the product you use delivers the required concentration in the final feed is essential for achieving the desired outcomes.

3. The Importance of Established, Research-Backed Brands

When selecting probiotics, it’s often beneficial to work with reputable companies that prioritize research and development. Some larger companies invest heavily in ensuring their probiotic strains are well-documented for efficacy and safety . These companies often hold patents and have a proven track record of quality, making them a safer choice compared to lesser-known or untested brands.

4. Synergistic Effects with Other Feed Additives

Combining probiotics with other feed additives, such as short- and medium-chain fatty acids, can enhance gut health further. This combination has been found to reduce the pathogenic bacterial load in the intestinal tract and improve villi development, leading to better feed conversion ratios (FCR) . This synergistic effect can be particularly useful in combating bacterial challenges while improving nutrient absorption and growth performance.

5. Long-Term Application and Early Inoculation

Based on practical experience, using probiotics early and consistently yields the best results. By inoculating the gut with beneficial bacteria early in the animal’s life, you can establish a stable and resilient microbial population. This approach prevents pathogenic bacteria from gaining a foothold, as pathogens like Salmonella replicate quickly once they establish themselves . For best results, start your probiotic regimen early.

27/07/2024


A vaccine is a biological preparation that provides active acquired immunity to a particular infectious or malignant disease.

is the vaccination ?
Vaccination is a simple, safe, and effective way of protecting you against harmful diseases, before you come into contact with them. It uses your body's natural defenses to build resistance to specific infections and makes your immune system stronger.

of vaccination failure.
1. The vaccination program
2. Improper storage and transportation of vaccine
3. Improper handling of the vaccine
4. Improper administration of the vaccine
5. The effect of passive immunity (maternal immunity)
6. Environmental stress factor
7. Health status of the flock
8. Immunosuppressive conditions
9. Genetic resistance
10. Excessive use of drugs lead to immune-suppressive bird causing poor immunity development
11. Interference

to overcome vaccination failure.

1. : means making of some preventive measures to prevent the introduce the disease into the farm by, proper cleaning and disinfection
2. Water quality,water sanitation
3. Insect control
4. Rodent control
5. Feed sanitation (treatment)
6. Provide proper and good managemental factor
7. Provide suitable temperature
8. Provide suitable relative humidity
9. Provide suitable stocking density
10. Provide good balanced ration
11. Provide vitamins and mineral therapy
12. Decreased uses of drugs
13. Provide a suitable ventilation system.

:

1. Make a suitable vaccination program according to the disease challenge in the farm area
2. all instructions of the manufacturer's , , , and
3. Use of well-trained persons
4. Make vaccination records to each cycle to discover any failure
5. Control measures during the cycle
6. Strict control at the gates of the farm
7. Strict control on the vehicles
8. Strict control on visitors
9. Strict control on pets ,wild birds and rodents
10. Put disinfectant in front gates, every poultry house
11. Proper disposal of dead birds.

If you think of a company as a family, regulatory affairs (RA) might *sometimes* be regarded as the least favored child ...
22/07/2024

If you think of a company as a family, regulatory affairs (RA) might *sometimes* be regarded as the least favored child in some families, as they are believed not being able to “bring money home” like their commercial or marketing siblings. This is a common misconception. Every member plays a role in keeping the “family” running. While RA may not directly generate revenue, their role is crucial for smooth operations, avoiding costly errors and maintaining a strong market presence. In other words, their contributions are essential to the company’s success, and here’s why:

1. Enabling Market Access:
RA professionals ensure products comply with all applicable laws and regulations. Without their expertise, products might not get approved for sale (what is there to sell if it is not approved in the first place?). In other words, they enable market access, which then leads to revenue generation.

2. Time to Market:
Time is money, efficient regulatory strategies can expedite the approval process, avoid unnecessary delays, allowing products to reach the market faster, leading to earlier revenue generation. This can be a significant competitive advantage.

3. Strategic Input:
RA teams offer valuable insights during product development stage, shaping strategies that align with regulatory requirements. This can lead to smooth product launches.

4. Risk Mitigation:
RA teams help mitigate risks by ensuring products comply with safety and efficacy standards. This reduces the likelihood of costly recalls, legal issues, and most importantly, tarnishing company’s reputation, which leads to severe financial implications.

5. Establishing Confidence:
Compliance with regulations instills confidence in consumers, stakeholders, and regulatory bodies, enhancing brand loyalty and profitability in long run.

What is an incubation period?👉The incubation period is the time it takes for an infection to develop after an organism h...
20/07/2024

What is an incubation period?
👉The incubation period is the time it takes for an infection to develop after an organism has been exposed to a disease-causing organism (such as bacteria, viruses, or fungi). The incubation period ends when the first signs or symptoms of the disease appear.
👉Incubation periods of different respiratory disease in poultry are given bellow.

05/07/2024

Giá ổn định cho Lysine và Threonine trong bối cảnh giá các loại axit amin nhỏ đang suy yếu
Thị trường axit amin Trung Quốc nhìn chung có giao dịch trầm lắng, người dùng cuối tiếp cận việc mua hàng một cách thận trọng và đứng ngoài cuộc.
Giá tryptophan đã giảm nhẹ, phản ánh việc các nhà sản xuất hạ giá chào và chiến lược mua theo yêu cầu của các doanh nghiệp thức ăn chăn nuôi ở hạ nguồn.
Các sản phẩm lysine đã chứng kiến ​​giao dịch chậm hơn ở Trung Quốc do tâm lý tìm kiếm hạ nguồn hạ nhiệt, dẫn đến sự ổn định tạm thời. Giá xuất khẩu của L-Lysine HCL 98% ở mức 1.360-1.400 USD/tấn và L-Lysine Sulfate 70% ở mức 680-710 USD/tấn. Hơn nữa, điều đáng chú ý là tình trạng thiếu hụt 98% L-Lysine HCL tại chỗ vẫn tiếp diễn, khiến lịch giao hàng kéo dài đến tháng 9 hoặc tháng 10.

Heat stress in dairy cows can affect various enzymes, impacting their overall health and productivity. Because this is s...
02/07/2024

Heat stress in dairy cows can affect various enzymes, impacting their overall health and productivity.

Because this is such an important and often underlooked issue during the summer months, I am listing some of the metabolic problems that will ultimately sacrifice your dairy’s profitability. It all starts at a molecular level!

Key enzymes affected by heat stress include:

1. **Aspartate Aminotransferase (AST):** Increased levels can indicate liver and muscle stress.

2. **Alanine Aminotransferase (ALT):** Elevated levels may signify liver damage.

3. **Alkaline Phosphatase (ALP):** Changes can reflect liver and bone metabolism disturbances.

4. **Lactate Dehydrogenase (LDH):** Increased levels can indicate muscle and tissue damage.

5. **Gamma-Glutamyl Transferase (GGT):** Elevated levels may be a marker of liver stress.

6. **Creatine Kinase (CK):** Increased levels indicate muscle damage or stress.

7. **Superoxide Dismutase (SOD):** Activity can decrease, reflecting oxidative stress.

8. **Catalase (CAT):** Reduced activity can indicate impaired antioxidant defenses.

9. **Glutathione Peroxidase (GPx):** Lower activity can signify oxidative stress and reduced detoxification capacity.

Quick observation: the word liver is repeated several times, during the list above. A basic knowledge of how important liver function is for an animal that synthesizes 100 lbs of milk daily will show that heat stress is an issue that definitely needs to be addressed.

Monitoring these enzymes can help in assessing the physiological impact of heat stress on dairy cows and implementing appropriate management strategies to mitigate its effects.

  impacts and role of Probiotic in Poultry industryProbiotics are being widely used in the poultry industry to prevent G...
20/06/2024

impacts and role of Probiotic in Poultry industry

Probiotics are being widely used in the poultry industry to prevent GI tract disorders and improve digestibility and performance. Probiotics are useful and friendly microbes. They are able to compete with the bad microbes and colonize our digestive system.
The mode of action of probiotics in poultry includes: (i) maintaining normal intestinal microflora by competitive exclusion and antagonism (ii) altering metabolism by increasing digestive enzyme activity and decreasing bacterial enzyme activity and ammonia production (iii) improving feed digestibility.
Gut Health:
Probiotics are food and health products that contribute live, beneficial microbes to the populations within your gut and elsewhere, in order to strengthen those communities.
Immunity:
Generally, live apathogenic microbial strains, singly or as multi-strain probiotics, belonging to genus Lactobacillus, Streptococcus, Bacillus, Enterococcus, Pediococcus, Aspergillus and Saccharomyces are used in poultry.
Growth and Feed Efficiency:
Probiotics can enhance growth performance and feed conversion ratio (FCR) by improving nutrient digestion and absorption. Probiotics might play an important role in improving overall productive performance through maintaining gut health, boosting immunity, decreasing disease load, and improving feed efficiency.
Pathogen Load:
Probiotics can compete with pathogenic bacteria for nutrients and adhesion sites in the gut, reducing the load of harmful bacteria such as Salmonella and E. coli.
the Effects of Stress:
Poultry can experience various stressors, such as environmental changes, which can negatively affect their health and performance.
Antibiotic Dependence:
With growing concerns about antibiotic resistance, probiotics offer a natural alternative to antibiotics for growth promotion and disease prevention. Their use can help reduce the reliance on antibiotics in poultry production.
Egg Production and Quality:
Probiotics supplementation in laying hen diets have been proven to improve hen's performance parameters including egg production, feed conversion ratio and egg quality(yolk color).
Mortality :
They might lower the number of "bad" bacteria in your gut that can cause illness or inflammation.By enhancing overall health and reducing disease incidence, probiotics can lower mortality and morbidity rates in poultry flocks.
:
Since probiotics do not result in the development and spread of microbial resistance, they offer immense potential to become an alternative to antibiotics. The present review reveals that probiotics could be successfully used as nutritional tools in poultry feeds for promotion of growth, modulation of intestinal microflora and pathogen inhibition and promoting meat quality of poultry.

10/06/2024

Một tuần được đặc trưng bởi các quỹ đạo giá khác nhau của các loại axit amin khác nhau nhưng giá L-Lysine Sulfate tăng nhẹ 70% ở cả Trung Quốc và Châu Âu

Thị trường axit amin Trung Quốc:
Thị trường tổng thể đã chứng kiến ​​các giao dịch thực tế ở mức trung bình trong tuần này, với tốc độ bổ sung chậm hơn từ các khu vực hạ nguồn và chiến lược tận tay được người dùng cuối áp dụng.
Giá L-Lysine Sulfate 70% tăng nhẹ, kích thích nhu cầu thị trường. Giá chào bán 98,5% L-Lysine HCL, Methionine và Threonine đã duy trì sự ổn định tạm thời, trong khi giá Valine và Tryptophan thể hiện xu hướng giảm kéo dài.
Theo thông tin thị trường, một số nhà sản xuất Trung Quốc đã tuần tự thực hiện các kế hoạch bảo trì cho dây chuyền sản xuất Lysine, Threonine và Methionine của họ. Nên theo dõi chặt chẽ việc phục hồi nhu cầu của người dùng cuối và tiến độ của các nhà sản xuất liên quan trong hoạt động bảo trì.

Thị trường axit amin châu Âu:
Ở châu Âu, giá các loại axit amin khác nhau có xu hướng khá khác biệt do các yếu tố như thuế hải quan và giá cước vận chuyển cao hơn.
Giá Methionine, Threonine, Valine và Tryptophan đã giảm ở các mức độ khác nhau trong tuần này, trong khi giá L-Lysine HCL 98,5% vẫn ổn định và giá L-Lysine Sulfate 70% đang tăng nhẹ.

10/06/2024

Dấu hiệu ổn định giá L-Lysine và sự suy yếu dai dẳng của giá Valine và Tryptophan
Tại thị trường axit amin Trung Quốc, giá Valine và Tryptophan duy trì xu hướng yếu do cung vượt cầu, giao dịch hạn chế và nhu cầu hạ nguồn trì trệ. Người dùng cuối đang tiếp cận việc mua sắm một cách thận trọng và chỉ bổ sung dựa trên nhu cầu tiêu dùng sắp xảy ra.
Theo thông tin thị trường, một số nhà sản xuất Trung Quốc đã tuần tự thực hiện các kế hoạch bảo trì cho dây chuyền sản xuất Lysine, Threonine và Methionine của họ.
Thị trường axit amin tổng thể ở châu Âu đang cho thấy sự ổn định. Giá L-Lysine Sulfate 70% dự kiến ​​sẽ tăng trong thời gian tới, do ý định mua hàng ở hạ nguồn tăng cao và chi phí hậu cần tăng.

GÓC CHIA SẺMột số hạn chế của kỹ thuật quản lý trại (đặc biệt là trại tư nhân)1. Làm việc trong 1 không gian đóng: Người...
10/06/2024

GÓC CHIA SẺ
Một số hạn chế của kỹ thuật quản lý trại (đặc biệt là trại tư nhân)
1. Làm việc trong 1 không gian đóng: Người quản lý kỹ thuật bị hạn chế trong 1 không gian làm việc của trại, ít được giao lưu, tiếp cận, học hỏi và cập nhật những kiến thức mới.
2. Nhìn mọi thứ thấy quen thuộc, quen mắt dẫn đến không phát hiện ra được vấn đề hoặc phát hiện ra muộn
3. Thiếu động lực để làm việc.
4. Thiếu mục tiêu để phấn đấu: cho rằng trại mình mọi thứ tốt rồi, không thể tốt hơn được nữa nên không cần phấn đấu, giữ như vậy là ổn rồi.
5. Thấy những ý kiến đóng góp, xây dựng của người khác là không phù hợp với trại, không hiểu trại bằng mình.
6. Quá nặng về kỹ thuật mà quên đi mất những kỹ năng khác rất quan trọng: quản trị nhân sự, kỹ năng giao việc, khen thưởng, kỷ luật, tạo động lực cho nhân viên, tuyển dụng và đào tạo nhân sự,....

THỨ MÀ TA KHÔNG BIẾT LÀ TA KHÔNG BIẾT SẼ HẠN CHẾ SỰ PHÁT TRIỂN CỦA BẢN THÂN TA.

Principles of antibiotic work.
08/06/2024

Principles of antibiotic work.

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