NEJM Journal Watch

NEJM Journal Watch Over 100 physician-editors regularly survey more than 250 medical journals and deliver only the most important clinical research findings.
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Biologic Classification of Hodgkin Lymphoma: A New Era for an Old Disease?Next-generation sequencing of circulating tumo...
01/24/2025

Biologic Classification of Hodgkin Lymphoma: A New Era for an Old Disease?

Next-generation sequencing of circulating tumor DNA revealed clinically relevant subtypes and a tool to monitor minimal residual disease. https://jwat.ch/4gbmY12

The H5N1 Outbreak: Clinical Case UpdatesWhile most human disease in the current influenza A(H5N1) outbreak has been mild...
01/23/2025

The H5N1 Outbreak: Clinical Case Updates

While most human disease in the current influenza A(H5N1) outbreak has been mild, severe cases have been reported; thus, vigilance is required.
https://jwat.ch/3WwkBix

NEJM Journal Watch Cardiology Top Stories of 2024See what the editors chose as the most important cardiology research of...
01/23/2025

NEJM Journal Watch Cardiology Top Stories of 2024

See what the editors chose as the most important cardiology research of the year: https://jwat.ch/3Wvr3Gq

A large retrospective study shows that higher fluid rates are associated with better outcomes in children with acute pan...
01/22/2025

A large retrospective study shows that higher fluid rates are associated with better outcomes in children with acute pancreatitis. https://jwat.ch/42lFLDE

Adjuvant Therapy for High-Risk Stage II Colon CancerOxaliplatin adds no overall survival benefit to 6 months of fluorina...
01/21/2025

Adjuvant Therapy for High-Risk Stage II Colon Cancer

Oxaliplatin adds no overall survival benefit to 6 months of fluorinated pyrimidine chemotherapy for these patients. https://jwat.ch/4hlgrlG

Use of a polypill to prevent cardiovascular disease in a majority Black and low-income patient cohort was predicted to b...
01/20/2025

Use of a polypill to prevent cardiovascular disease in a majority Black and low-income patient cohort was predicted to be lifesaving and cost-effective. https://jwat.ch/42i7G7J

Does a higher hemoglobin target improve outcomes in aneurysmal subarachnoid hemorrhage? https://jwat.ch/4fWvRvn
01/19/2025

Does a higher hemoglobin target improve outcomes in aneurysmal subarachnoid hemorrhage? https://jwat.ch/4fWvRvn

Is “As-Needed” Blood Pressure Medication Really Needed in Inpatients?Treating inpatients who had asymptomatic BP elevati...
01/17/2025

Is “As-Needed” Blood Pressure Medication Really Needed in Inpatients?

Treating inpatients who had asymptomatic BP elevations was associated with risk for acute kidney injury, myocardial infarction, stroke, or death. https://jwat.ch/3WoEUyj

Combined treatment with talquetamab plus teclistamab provided durable responses in patients with relapsed and refractory...
01/17/2025

Combined treatment with talquetamab plus teclistamab provided durable responses in patients with relapsed and refractory myeloma, albeit with high rates of infection. https://jwat.ch/40xeVqZ

Combined analysis of two randomized trials showed that levofloxacin prevented development of disease in people exposed t...
01/16/2025

Combined analysis of two randomized trials showed that levofloxacin prevented development of disease in people exposed to multidrug-resistant tuberculosis. https://jwat.ch/4aoRbsw

People with post-traumatic stress disorder had greater response to sertraline plus brexpiprazole than to sertraline alon...
01/15/2025

People with post-traumatic stress disorder had greater response to sertraline plus brexpiprazole than to sertraline alone in a recent study. https://jwat.ch/40BkftC

In a practice-changing, 6-month, randomized trial, higher-dose erenumab was efficacious in treating nonopioid medication...
01/15/2025

In a practice-changing, 6-month, randomized trial, higher-dose erenumab was efficacious in treating nonopioid medication-overuse headache in chronic migraine. https://jwat.ch/40j1zx0

The Department of Health and Human Services has revised its guidelines on managing children exposed to or living with HI...
01/14/2025

The Department of Health and Human Services has revised its guidelines on managing children exposed to or living with HIV. Dr. Deborah Lehman highlights what's changed. https://jwat.ch/4gTlud2

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Videos

Dr. Inas Abuali chats with Dr. Anjali Sharathkumar and Dr. Michael Williams about the major clinical takeaways from the American Society of Hematology annual meeting. https://jwat.ch/3VLUT9g

For NEJM Group’s coverage of the ASH Annual Meeting, Dr. Inas Abuali talks with Dr. Mrunanjali Gaddam about the prevalence and outcomes of pulmonary hypertension in patients hospitalized with sickle cell crisis. Watch the full interview here: https://jwat.ch/3Vyjuyn

Ahead of the American Society of Hematology 2024 Annual Meeting, Dr. Inas Abuali talks to Dr. Anjali Sharathkumar and Dr. Michael Williams about what they are most looking forward to at the conference. https://jwat.ch/4gm5saY

Dr. Opeyemi Olabisi and Dr. Meghan Sise discuss the highlights and themes of Kidney Week 2024 with Dr. Ali Raja. https://jwat.ch/4hwam6T

NEJM Group's conference guides Dr. Carlos del Rio and Dr. Rajesh Gandhi share their IDWeek 2024 highlights with Dr. Lauren Westafer. Watch the full video: https://jwat.ch/4e0yxHA

Dr. Meghan Sise and Dr. Opeyemi Olabisi, NEJM Group's guides for Kidney Week 2024, talk to Dr. Ali Raja about what topics will generate the most excitement at the conference. Watch the 10-minute video: https://jwat.ch/4dZddlN

Dr. Carlos del Rio and Dr. Rajesh Gandhi, NEJM Group's expert guides for IDWeek 2024, talk to Dr. Lauren Westafer about what they’re most excited about at this year's conference. Watch the full video: https://jwat.ch/4haqj28

Dr. André Sofair talks with Dr. Robert Dreicer, Dr. William Gradishar, and Dr. Jyoti Patel — three of the four oncologists who guided our coverage of ESMO Congress 2024 — about the biggest takeaways from the conference. https://jwat.ch/4ewayQZ

Ahead of the European Society for Medical Oncology (ESMO) Congress 2024, Dr. André Sofair sat down with our clinician-guides — Drs. William Gradishar, Robert Dreicer, David Ilson, and Jyoti Patel — to discuss the studies they're most looking forward to hearing more about. https://jwat.ch/3AX80Nr

In an interview with NEJM Group’s Dr. Jaye Hefner, our clinician-guides, Dr. Nadine Palermo and Dr. Ole-Petter Hamnvik, discuss the biggest takeaways from the American Diabetes Association's Scientific Sessions. Watch the 9-minute interview here: https://jwat.ch/45FQEQx

In an interview with NEJM Group’s Dr. Jaye Hefner, Dr. Atul Malhotra talks about the results of the phase 3 SURMOUNT-OSA studies that looked at tirzepatide for the treatment of obstructive sleep apnea and obesity. Results were presented at the American Diabetes Association Scientific Sessions. https://jwat.ch/3RGcuxA

The American Diabetes Association 2024 Scientific Sessions begin this week. Dr. Jaye Hefner talks with our clinician-guides Dr. Ole-Petter Hamnvik and Dr. Nadine Palermo about what they’re most looking forward to at this year's meeting. https://jwat.ch/45wWvri

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