NEJM Journal Watch

NEJM Journal Watch Over 100 physician-editors regularly survey more than 250 medical journals and deliver only the most important clinical research findings.
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A Randomized Trial of Transcatheter Edge-to-Edge Repair for Severe Tricuspid RegurgitationAlthough major cardiovascular ...
12/09/2024

A Randomized Trial of Transcatheter Edge-to-Edge Repair for Severe Tricuspid Regurgitation

Although major cardiovascular events were not reduced at 1 year, this study confirms a benefit in patient-reported outcome measures. https://jwat.ch/3ZFPwuE

Is There a Role for Prostate Radiotherapy in De Novo Metastatic Prostate Cancer?A radiographic progression-free survival...
12/08/2024

Is There a Role for Prostate Radiotherapy in De Novo Metastatic Prostate Cancer?

A radiographic progression-free survival benefit was shown in people with low-volume disease receiving androgen deprivation therapy with intensification. https://jwat.ch/3VpgRi8

Are rifampin and gentamicin strictly necessary for staphylococcal prosthetic valve endocarditis? https://jwat.ch/41FhQiv
12/07/2024

Are rifampin and gentamicin strictly necessary for staphylococcal prosthetic valve endocarditis? https://jwat.ch/41FhQiv

In a recent randomized trial, fezolinetant appeared effective and safe for managing vasomotor symptoms of menopause in w...
12/06/2024

In a recent randomized trial, fezolinetant appeared effective and safe for managing vasomotor symptoms of menopause in women for whom hormone therapy wasn't an option. https://jwat.ch/3VogR1Y

12/06/2024

Ahead of the American Society of Hematology 2024 Annual Meeting, Dr. Inas Abuali talks to Dr. Anjali Sharathkumar and Dr. Michael Williams about what they are most looking forward to at the conference. https://jwat.ch/4gm5saY

Early surgery or endoscopy for painful chronic pancreatitis? In a randomized trial, surgery appeared to be more effectiv...
12/06/2024

Early surgery or endoscopy for painful chronic pancreatitis? In a randomized trial, surgery appeared to be more effective, but caveats apply, writes Dr. David Bjorkman. https://jwat.ch/3VrI7wx

The new nonsteroidal cream roflumilast was modestly effective for eczema in short-term, placebo-controlled trials. https...
12/05/2024

The new nonsteroidal cream roflumilast was modestly effective for eczema in short-term, placebo-controlled trials. https://jwat.ch/4glu6c2

Patients admitted to medical floors with community-acquired pneumonia did not benefit from systemic corticosteroids. htt...
12/04/2024

Patients admitted to medical floors with community-acquired pneumonia did not benefit from systemic corticosteroids. https://jwat.ch/3VlClg0

A novel clinical score, the DIAS3, adequately discriminates risk for late seizures after cerebral venous thrombosis usin...
12/04/2024

A novel clinical score, the DIAS3, adequately discriminates risk for late seizures after cerebral venous thrombosis using six readily available clinical variables. https://jwat.ch/3ZLBYy5

Secondary analyses of the FINEARTS-HF trial provide more data on finerenone for heart failure with preserved or mildly r...
12/03/2024

Secondary analyses of the FINEARTS-HF trial provide more data on finerenone for heart failure with preserved or mildly reduced ejection fraction. https://jwat.ch/3Vm0CT3

A large, randomized trial confirms that tenecteplase is noninferior to alteplase for patients with acute ischemic stroke...
12/02/2024

A large, randomized trial confirms that tenecteplase is noninferior to alteplase for patients with acute ischemic stroke. https://jwat.ch/3Z5M239

Should urea be used for managing syndrome of inappropriate antidiuretic hormone (SIADH) secretion? A recent meta-analysi...
12/02/2024

Should urea be used for managing syndrome of inappropriate antidiuretic hormone (SIADH) secretion? A recent meta-analysis suggests that it is safe and effective. https://jwat.ch/49bxFiv

Can zoledronate protect against bone loss in people who discontinue denosumab? https://jwat.ch/3Z7I623
12/01/2024

Can zoledronate protect against bone loss in people who discontinue denosumab? https://jwat.ch/3Z7I623

Some ID Things to Be Grateful for This Holiday Season — 2024 Edition Dr. Paul Sax says sweet potato casserole with marsh...
11/30/2024

Some ID Things to Be Grateful for This Holiday Season — 2024 Edition

Dr. Paul Sax says sweet potato casserole with marshmallows didn't make the cut.
https://jwat.ch/3CP3At2

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Videos

Ahead of the American Society of Hematology 2024 Annual Meeting, Dr. Inas Abuali talks to Dr. Anjali Sharathkumar and Dr. Michael Williams about what they are most looking forward to at the conference. https://jwat.ch/4gm5saY

Dr. Opeyemi Olabisi and Dr. Meghan Sise discuss the highlights and themes of Kidney Week 2024 with Dr. Ali Raja. https://jwat.ch/4hwam6T

NEJM Group's conference guides Dr. Carlos del Rio and Dr. Rajesh Gandhi share their IDWeek 2024 highlights with Dr. Lauren Westafer. Watch the full video: https://jwat.ch/4e0yxHA

Dr. Meghan Sise and Dr. Opeyemi Olabisi, NEJM Group's guides for Kidney Week 2024, talk to Dr. Ali Raja about what topics will generate the most excitement at the conference. Watch the 10-minute video: https://jwat.ch/4dZddlN

Dr. Carlos del Rio and Dr. Rajesh Gandhi, NEJM Group's expert guides for IDWeek 2024, talk to Dr. Lauren Westafer about what they’re most excited about at this year's conference. Watch the full video: https://jwat.ch/4haqj28

Dr. André Sofair talks with Dr. Robert Dreicer, Dr. William Gradishar, and Dr. Jyoti Patel — three of the four oncologists who guided our coverage of ESMO Congress 2024 — about the biggest takeaways from the conference. https://jwat.ch/4ewayQZ

Ahead of the European Society for Medical Oncology (ESMO) Congress 2024, Dr. André Sofair sat down with our clinician-guides — Drs. William Gradishar, Robert Dreicer, David Ilson, and Jyoti Patel — to discuss the studies they're most looking forward to hearing more about. https://jwat.ch/3AX80Nr

In an interview with NEJM Group’s Dr. Jaye Hefner, our clinician-guides, Dr. Nadine Palermo and Dr. Ole-Petter Hamnvik, discuss the biggest takeaways from the American Diabetes Association's Scientific Sessions. Watch the 9-minute interview here: https://jwat.ch/45FQEQx

In an interview with NEJM Group’s Dr. Jaye Hefner, Dr. Atul Malhotra talks about the results of the phase 3 SURMOUNT-OSA studies that looked at tirzepatide for the treatment of obstructive sleep apnea and obesity. Results were presented at the American Diabetes Association Scientific Sessions. https://jwat.ch/3RGcuxA

The American Diabetes Association 2024 Scientific Sessions begin this week. Dr. Jaye Hefner talks with our clinician-guides Dr. Ole-Petter Hamnvik and Dr. Nadine Palermo about what they’re most looking forward to at this year's meeting. https://jwat.ch/45wWvri

A Final Chat with Our Clinician-Guides for ASCO 2024 The oncologists who guided our coverage this year discuss key takeaways from the conference. Watch the full video: https://jwat.ch/4aSSKgI

NEJM Group's Dr. Inas Abuali talks to Dr. Suresh Ramalingam about the primary results of the phase 3 LAURA trial of osimertinib after chemoradiotherapy in patients with unresectable, EGFR-mutated stage III non–small-cell lung cancer. Results were presented at ASCO 2024. Watch the full interview: https://jwat.ch/3X62PDJ

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