APL Bioengineering

01/17/2025

Noninvasive biopsy for gynecological studies - the opportunity

Fractional-pixel CO2 laser therapy shows promise for treating the genitourinary syndrome of menopause (GSM). Nevertheless, it remains controversial in the field

01/15/2025

Which relationship between chronic kidney disease and performance of vascular graft? A solid response based on an in vivo study is given by the Medical Center of the Utrecht University.

Vascular in situ tissue engineering encompasses a single-step approach with a wide adaptive potential and true off-the-shelf availability for vascular grafts. H

01/13/2025

How can we calibrate computational models of thrombosis? UK researchers answer by presenting the first in silico study of spontaneous thrombosis prevalence across a broader set of aneurysm phenotypes.

How prevalent is spontaneous thrombosis in a population containing all sizes of intracranial aneurysms? How can we calibrate computational models of thrombosis

01/10/2025

A 3D real-scale blood–brain barrier (BBB) microfluidic system assembled by magnetic forces is the novel proposal by IIT researchers for screening

In recent years, the need for highly predictive brain cancer models to test new anticancer compounds and experimental therapeutic approaches has significantly i

01/09/2025

We developed tunable 3D scaffolds on-chip to mimic brain tissue, enabling real-time study of how cancer cells invade and interact with blood vessels. One step closer to understanding how cancer spreads.

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The high mortality associated with certain cancers can be attributed to the invasive nature of the tumor cells. Yet, the complexity of studying invasion hinders

01/08/2025

Electrodes to perform and to avoid problems of skin preparation are working efficiently? Yes, if is used. Rylie Green and colleague illustrate how this polymer can work!

Conventional wet Ag/AgCl electrodes are widely used in electrocardiography, electromyography (EMG), and electroencephalography (EEG) and are considered the gold

01/06/2025

Italian CNR researchers recognize neuroblastoma circulating tumor cells in liquid biopsy: an intelligent solution at the lab-on-the-chip level.

01/03/2025

New findings from Chongqing University suggests that when under shear stress, TET1s is reduced and damages endothelial cells.

Vascular endothelial polarity induced by blood flow plays crucial roles in the development of atherosclerosis. Loss of endothelial polarity leads to an increase

01/03/2025

Congratulations to Dr. Jenny Jiang, the 2025 CMBE (Cellular and Molecular Bioengineering) Momentum Award Winner! We were honored to sponsor this award. 🏆

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https://aippub.org/4j3LaFi

01/01/2025

Taking up all the air the room': cell–cell interaction affects oxygen dynamics via Università di Pisa

Accurately modeling oxygen transport and consumption is crucial to predict metabolic dynamics in cell cultures and optimize the design of tissue and organ model

12/30/2024

This research examines textile techniques for cardiac patches, vascular grafts, and stents, focusing on parameters that influence their properties and suggesting future research for improved outcomes.

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In cardiovascular therapeutics, procedures such as heart transplants and coronary artery bypass graft are pivotal. However, an acute shortage of organ donors in

12/27/2024

: engineers control cell stemness via 3D micro-fabricated lattice substrate in APLBioengeering paper from

Mechanical stimuli from the extracellular environment affect cell morphology and functionality. Recently, we reported that mesenchymal stem cells (MSCs) grown i

12/25/2024

I'm a Survinin! New APL Bioengeering paper reveals survivin's impact on the modulation of cell phenotype & proliferation.

Stiffened arteries are a pathology of atherosclerosis, hypertension, and coronary artery disease and a key risk factor for cardiovascular disease events. The in

12/23/2024

Survivin of the fittest! Check out the role of survivin in vascular mechanics and disease , , ,

Vascular dysfunction is a common cause of cardiovascular diseases characterized by the narrowing and stiffening of arteries, such as atherosclerosis, restenosis

12/20/2024

Efficient, cost-effective, and highly tunable molecular engineered DNA microladder-based soft hydrogels - super cool! , , ,

Soft, biocompatible, and tunable materials offer biomedical engineers and material scientists programmable matrices for a variety of biomedical applications. In

12/20/2024

The genes, involved in both diseases, could serve as targets for diagnosis and treatment.

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WASHINGTON, Nov. 5, 2024 – Rheumatoid arthritis is a common disease affecting an estimated 17 million people worldwide. The disease is caused by immune cells attacking the [...]

12/18/2024

Check out this disruptive tech - Organic molecular phototransducers that allow wiring- and electrode-free tissue modulation for highly resolved cardiac tissue stimulation , , , ,

Light is recognized as an accurate and noninvasive tool for stimulating excitable cells. Here, we report on a non-genetic approach based on organic molecular ph

12/16/2024

Modelling IVD regeneration is challenging - Lazaro-Pacheco et al give us a state-of-the-art picture on the importance of biomechanics in doing so! , , , ,

Low back pain is the leading cause of disability, producing a substantial socio-economic burden on healthcare systems worldwide. Intervertebral disc (IVD) degen