JAMA Neurology

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Official page for JAMA Neurology http://jamaneuro.com, an international, peer-reviewed journal published weekly online and monthly in print.

Long-term exposure to wildfire smoke is associated with an increased risk of dementia, particularly among racially minor...
01/26/2025

Long-term exposure to wildfire smoke is associated with an increased risk of dementia, particularly among racially minoritized patient subgroups and those living in high-poverty areas in Southern California. https://ja.ma/3PMFan0

The representation of women and racial/ethnic minorities among US neurology faculty still lags behind the overall US pop...
01/25/2025

The representation of women and racial/ethnic minorities among US neurology faculty still lags behind the overall US population, especially in senior academic ranks and leadership positions. https://ja.ma/40jEudO

Most viewed in the last 7 days from JAMA Neurology: Several factors, mostly modifiable, were associated with a higher ri...
01/25/2025

Most viewed in the last 7 days from JAMA Neurology: Several factors, mostly modifiable, were associated with a higher risk of young-onset .

https://ja.ma/40WrnRv

While children of women with epilepsy did not differ in neuropsychological abilities at age 6, the level of antiseizure ...
01/24/2025

While children of women with epilepsy did not differ in neuropsychological abilities at age 6, the level of antiseizure medication exposure during pregnancy was associated with verbal abilities. https://ja.ma/40EzGkx

A man aged 61 years presented with chronic progressive weakness and gait dysfunction over a 4-year period. Take the Clin...
01/23/2025

A man aged 61 years presented with chronic progressive weakness and gait dysfunction over a 4-year period. Take the Clinical Challenge. What is your diagnosis?

https://ja.ma/3E9i9Z5

Most viewed in the last 7 days from JAMA Neurology: This Viewpoint discusses using digital biomarkers for neurodegenerat...
01/23/2025

Most viewed in the last 7 days from JAMA Neurology: This Viewpoint discusses using digital biomarkers for neurodegenerative disease.

https://ja.ma/42iuX9h

Thrombolysis with prourokinase was not superior to standard care to improve the functional outcomes for patients with mi...
01/22/2025

Thrombolysis with prourokinase was not superior to standard care to improve the functional outcomes for patients with mild ischemic stroke within 4.5 hours of symptom onset and had a similar safety profile.

https://ja.ma/3C80i4b

Autoantibodies targeting the astrocytic intermediate filament protein vimentin were identified in patients with previous...
01/21/2025

Autoantibodies targeting the astrocytic intermediate filament protein vimentin were identified in patients with previously undifferentiated meningoencephalomyelitis. https://ja.ma/42oh75A

ARIA-E in Alzheimer disease is more likely in those with APOE ε4, microhemorrhages, low CSF Aβ42, and high Fazekas score...
01/20/2025

ARIA-E in Alzheimer disease is more likely in those with APOE ε4, microhemorrhages, low CSF Aβ42, and high Fazekas scores, but it does not generally worsen long-term cognition or function. https://ja.ma/3DQRYWS

This Viewpoint discusses using digital biomarkers for neurodegenerative disease. https://ja.ma/4gIwry9
01/19/2025

This Viewpoint discusses using digital biomarkers for neurodegenerative disease. https://ja.ma/4gIwry9

Case report describes a young patient with multiple posterior circulation embolic stroke of undermined source who was fo...
01/18/2025

Case report describes a young patient with multiple posterior circulation embolic stroke of undermined source who was found to have a V3 segment vertebral artery web. https://ja.ma/40fGh3n

Most viewed in the last 7 days from JAMA Neurology: This Viewpoint discusses using digital biomarkers for neurodegenerat...
01/18/2025

Most viewed in the last 7 days from JAMA Neurology: This Viewpoint discusses using digital biomarkers for neurodegenerative disease.

https://ja.ma/4ap8zNu

In this randomized clinical trial, iron chelation with deferiprone accelerated Alzheimer disease progression. https://ja...
01/17/2025

In this randomized clinical trial, iron chelation with deferiprone accelerated Alzheimer disease progression. https://ja.ma/3PzaRAf

Viewpoint: Although genetic therapies have shown significant promise, a centralized registry for systematic data sharing...
01/16/2025

Viewpoint: Although genetic therapies have shown significant promise, a centralized registry for systematic data sharing could enhance patient safety and improve therapeutic outcomes. https://ja.ma/4hdS7Cc

Most viewed in the last 7 days from JAMA Neurology: Anti-CGRP mAbs did not appear to elevate CVD risk compared with onab...
01/16/2025

Most viewed in the last 7 days from JAMA Neurology: Anti-CGRP mAbs did not appear to elevate CVD risk compared with onabotulinumtoxinA among Medicare beneficiaries with migraine, a population underrepresented in clinical trials.

https://ja.ma/3DRWd4A

The Get With the Guidelines-Stroke program has improved stroke care quality since 2003, increasing the population-level ...
01/15/2025

The Get With the Guidelines-Stroke program has improved stroke care quality since 2003, increasing the population-level value measured in quality-adjusted life-years. https://ja.ma/4fUVmgE

Brain hypometabolism, detected by FDG-PET, begins in the prodromal stages of dementia with Lewy bodies (DLB) and progres...
01/14/2025

Brain hypometabolism, detected by FDG-PET, begins in the prodromal stages of dementia with Lewy bodies (DLB) and progressively worsens. https://ja.ma/4hg45LH

In patients with hereditary transthyretin amyloidosis with polyneuropathy, treatment with patisiran resulted in better o...
01/13/2025

In patients with hereditary transthyretin amyloidosis with polyneuropathy, treatment with patisiran resulted in better outcomes and survival than those receiving placebo. https://ja.ma/3WcZOjX

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