Advances in Clinical and Experimental Medicine

Advances in Clinical and Experimental Medicine 5-Year IF 2.0, IF 1.9, JCI (2024) 0.43, Scopus CiteScore 4.3, H-index 49 (SJR)
Initial editorial assessment and first decision within 24 h

🚀 Ahead of print 🚀Nutrition & exercise for brain health: Enhancing cognitive function and neuroplasticityHighlights• Nut...
12/09/2025

🚀 Ahead of print 🚀

Nutrition & exercise for brain health: Enhancing cognitive function and neuroplasticity

Highlights

• Nutrition and exercise synergy enhances brain health and neuroplasticity: Combined diet and physical activity fortify brain structure, synaptic function, and learning capacity.
• Antioxidants, omega-3 fatty acids, polyphenols, and the MIND diet boost cognitive function: These key nutrients reduce oxidative stress and support memory, attention, and executive performance.
• Regular physical activity elevates mood, attention, memory, and overall cognitive performance: Aerobic and resistance training increase cerebral blood flow and neurotrophic factors for sharper thinking.
• Mechanistic insights still emerging on diet- and exercise-driven brain benefits: Ongoing research aims to unravel the molecular pathways linking nutritional compounds and exercise stimuli to neural health.

https://advances.umw.edu.pl/en/ahead-of-print/208533/

🚀Ahead of print 🚀Family medicine: Discovering new fields for research and clinical care in the current worldHighlights• ...
11/09/2025

🚀Ahead of print 🚀

Family medicine: Discovering new fields for research and clinical care in the current world

Highlights

• PHC & UHC: PHC alone can’t deliver UHC; system-level reform and political will are essential.
• Eudaimonia vs hedonism: Blending purpose-driven (eudaimonic) and pleasure-driven (hedonic) well-being can reduce burnout.
• Lifelong purpose: Support eudaimonic motivation throughout physicians’ careers, not just in training.
• Sense of coherence: Comprehensibility, manageability, and meaningfulness predict better health and coping.
• Compassion’s satisfaction: Compassion – for others and self – deepens care and guards against burnout.
• Research gaps: Study on suffering, hope, loneliness, conflict, and climate change to be addressed by the primary and public health researchers and practitioners.
• Six research priorities: Boost evidence, funding, leadership, team science, psychosocial and cultural determinants of health.

https://advances.umw.edu.pl/en/ahead-of-print/208659/

📢From Bench to Bedside: Advances in Neuroinflammation and CNS Disorder Research 📢📢 Call for submissions of an Expression...
10/09/2025

📢From Bench to Bedside: Advances in Neuroinflammation and CNS Disorder Research 📢

📢 Call for submissions of an Expression of Interest for an Adv Clin Exp Med Special Collection on Neuroinflammation in CNS Disorders 📢

The editors of this special collection invite submissions exploring the latest advances in clinical and experimental research on neuroinflammation in the central nervous system (CNS). Neuroinflammation is at the forefront of neuroscience, shaping our understanding of CNS disorders such as neurodegenerative disease, psychiatric disorders, and traumatic brain injuries. This collection aims to unite diverse perspectives, fostering insights into the complex cellular and molecular mechanisms driving neuroinflammatory processes. We encourage the submission of original research, meta-analyses, and comprehensive review articles that shed light on diagnostic, therapeutic, and mechanistic aspects of CNS inflammation.
We are particularly interested in manuscripts that explore the interplay between immune cells, neurons, and glia, with a focus on translational research. Contributions detailing innovative diagnostic approaches, therapeutic targets, or computational models are highly welcome. Join this effort to advance the boundaries of neuroinflammation research and contribute to groundbreaking findings that bridge laboratory and clinical neuroscience.

Topic and format
Advances in Clinical and Experimental Medicine is therefore seeking original papers for a Special Collection focused on the following themes:
• Neuroimmune Interactions in Health and Disease
• Cellular and Molecular Pathways of Neuroinflammation
• Neuroinflammation and Neurodegeneration: Cause or Consequence?
• Innovative Imaging and Biomarkers for CNS Inflammation
• Therapeutic Interventions Targeting Neuroinflammation
• Role of Microglia and Astrocytes in Neuroinflammatory Diseases

MORE INFORMATION
https://advances.umw.edu.pl/en/neuroinflammation-in-cns-disorders



Masaru Tanaka

Physical fitness before stem cell transplant: why it matters more than you think 🏃‍♀️🏃‍♂️Imagine having to run a maratho...
09/09/2025

Physical fitness before stem cell transplant: why it matters more than you think 🏃‍♀️🏃‍♂️

Imagine having to run a marathon right after months of battling blood cancer and undergoing chemotherapy. This is what many patients face before hematopoietic stem cell transplantation (HSCT) – a life-saving but physically demanding procedure.

A new study from Wroclaw Medical University published at Advances in Clinical and Experimental Medicine shows that most patients with blood cancers start this process already physically weakened. And that may impact the success of the transplant itself.

🧪 Researchers tested simple measures of fitness – walking, standing up, turning around – in 65 patients and compared them to 200 healthy individuals. The differences were striking:
– patients walked 160 meters less in 6 minutes,
– completed 4 fewer sit-to-stand repetitions,
– and performed worse in mobility tests.

The conclusion? Cancer and previous treatments deplete strength – before transplant even begins. That’s why exercise-based preparation, or prehabilitation, may give patients a real survival advantage.

🎧 Learn more in the latest podcast episode:
▶️ https://soundcloud.com/wmu-pl/physical-fitness-before-stem-cell-transplants?si=09d00ef218fb4f32a3b581a4100b0a05&utm_source=clipboard&utm_medium=text&utm_campaign=social_sharing

📖 Read the full article in Advances in Clinical and Experimental Medicine:
➡️ https://advances.umw.edu.pl/en/article/2025/34/8/1343/

Authors: Michał Chmielewski, Agnieszka Szeremet, Paula Jabłonowska-Babij, Maciej Majcherek, Anna Czyż, Natalia Bursiewicz, Tomasz Wróbel, Iwona Malicka

📢Meet the authors of our latest editorial!📢Dr. Claudia Giorgetti✔️SHORT BIOhttps://ojs.umw.edu.pl/files/acem/CV_Giorgett...
09/09/2025

📢Meet the authors of our latest editorial!📢

Dr. Claudia Giorgetti

✔️SHORT BIO
https://ojs.umw.edu.pl/files/acem/CV_Giorgetti-19_250828_170538.pdf

Prof. Arianna Giorgetti

✔️SHORT BIO
https://ojs.umw.edu.pl/files/acem/CV%20AG%20%281%29.pdf

Prof. Rafael Boscolo-Berto

✔️SHORT BIO
https://ojs.umw.edu.pl/files/acem/CV%20RBB%20%281%29.pdf

✔️ READ THE EDITORIAL

Establishing new boundaries for medical liability: The role of AI as a decision-maker

https://advances.umw.edu.pl/en/ahead-of-print/208596/

✔️MINI-INTERVIEW

1. Assigning authorship to an AI tool in case of scientific papers is not practiced, while – as you clearly outline in your paper – there is such need in case of clinical decision support systems (CDSSs). What are the key differences between these 2 instances of AI use?

Authorship of scientific works is grounded in the recognition of creativity: since AI is generally not considered capable of genuine creativity, authorship is not attributed to it, so human authors remain fully responsible for the content. CDSSs, by contrast, can directly influence clinical decisions with a significant and direct impact on patient health. Here, the issue is not authorship in the sense of intellectual credit or copyright, but rather the need to attribute responsibility to the developers of CDSSs, where appropriate, to ensure trust, safety, and accountability. The goal is to delineate roles, responsibilities, and liability where AI contributes to or influences clinical decision-making.

2. In your opinion, is it a real danger that medical facilities’ managers will push medical professionals to rely more and more on AI to enhance efficiency at the expense of real oversight over AI tools?

Medical facilities’ managers are undoubtedly under pressure to reduce costs, especially given the growing demand for healthcare services and the shortage of professionals, so it seems likely that, where possible, they may encourage greater reliance on AI. On the other hand, maintaining robust oversight might be prioritized if a significant risk of liability is perceived. Improper over-reliance on AI by inexperienced and undertrained healthcare professionals certainly represent a concrete risk that can lead to serious health consequences. In order to prevent and avoid the negative effects of AI tools introduced in the healthcare system, education and training of the professionals is a key element, that might allow to obtain time efficiency without increasing adequate oversight.

3. What is the role of forensic medicine in cases of suspected malpractice or error involving the use of AI in medicine?

The role of forensic medicine in each case of suspected malpractice, including cases involving the use of AI in medicine, is to understand whether an error was committed, e.g., whether it was preventable and avoidable or not, and whether a harm or death was causally linked to such error. The involvement of AI introduces greater complexity in the landscape of liability because AI functions as a "new actor" whose responsibility may be full or partial, complicating how accountability is attributed among healthcare providers, AI developers, and others. Moreover, legal frameworks are still evolving to address these nuanced responsibilities, emphasizing the need for interdisciplinary collaboration and transparency in AI use.

📢Out in Health: Health Equity and Innovations in LGBT+ Care📢Call for submissions of an Expression of Interest for an Adv...
08/09/2025

📢Out in Health: Health Equity and Innovations in LGBT+ Care📢

Call for submissions of an Expression of Interest for an Adv Clin Exp Med Special Collection on LGBT+ Health Equity and Innovation

Handling Editors

Assoc. Prof. Michał Czapla (Division of Scientific Research and Innovation in Emergency Medical Service, Department of Emergency Medical Service, Faculty of Nursing and Midwifery, Wroclaw Medical University, Wrocław, Poland; Group of Research in Care (GRUPAC), Faculty of Health Sciences, University of La Rioja, Logroño, Spain; ORCID 0000-0002-4245-5420) [email protected]

Dr. Anthony Dissen (Stockton University, Galloway, USA; ORCID 0000-0003-0828-387X) [email protected]

This Call for Submissions invites Expressions of Interest for a Special Collection of Advances in Clinical and Experimental Medicine, focusing on LGBT+ health equity and innovation.

LGBT+ individuals around the world face unique and persistent health disparities driven by stigma, discrimination, and systemic exclusion from healthcare systems. These inequities result in significantly worse physical and mental health outcomes and limit access to inclusive, culturally competent care.

This Special Collection will offer researchers and clinicians an opportunity to publish original research, meta-analyses, and review articles that address these disparities and propose inclusive, personalized, and innovative solutions to improve health outcomes for LGBT+ populations.

This Call welcomes submissions on (but not limited to):

* Mental Health & Well-being
* Sexual & Reproductive Health
* Transgender & Gender-Diverse Health
* Equity in Healthcare Access
* Social Determinants of Health
* Stigma & Healthcare Avoidance
* Community & Public Health Initiatives
* Intersectionality in Health

MORE INFORMATION
https://advances.umw.edu.pl/en/lgbt


Uniwersytet Medyczny im. Piastów Śląskich we Wrocławiu
Dr hab. Michał Czapla

Types of articles in Advances in Clinical and Experimental Medicine in 2021 and 2022: Editors’ perspectiveThe present ed...
07/09/2025

Types of articles in Advances in Clinical and Experimental Medicine in 2021 and 2022: Editors’ perspective

The present editorial summarizes the last 2 calendar years of Advances in Clinical and Experimental Medicine (ACEM) publication (2021 and 2022). The specific aims were: 1) To clarify the classification of papers published in ACEM; 2) To present motivations behind choosing this classification; 3) To show how this classification is reflected in citations. Six categories of papers published in ACEM are presented: editorials, meta-analyses, reviews (including systematic reviews), multicenter studies, research-in-progress studies, and research letters; lack of clear definitions for editorials, research letters and research-in-progress studies is discussed. Thematic fields covered by all categories in 2021 and 2022 are presented and differences in this regard between 2021 and 2022 are highlighted. Reasons for not publishing case reports (CRs) are discussed, with some of the debate on this issue in medical literature summarized. The article type classification used in ACEM in only one of many possible solutions and may be modified in the future – it should be both clear for the authors and allow for orientation in the journal’s content. The motivation for choosing the employed categories stem both from their position on the accepted levels of evidence in evidence-based medicine (EBM) and their potential to be cited.

https://advances.umw.edu.pl/en/ahead-of-print/176003/

📢New statistical guidelines📢Editors of Adv Clin Exp Med are well aware that correct analysis of statistical data and rep...
07/09/2025

📢New statistical guidelines📢

Editors of Adv Clin Exp Med are well aware that correct analysis of statistical data and reporting the results of such analysis is not easy even for experienced researchers, because we are dealing with really, not only ostensibly complicated matters. Specialists from the Centre for Statistical Analysis at the Wroclaw Medical University want to provide you as much help and guidance as possible, and have prepared these detailed guidelines for all authors wishing to submit their manuscripts to our journal.

Should you have any questions regarding statistics in Adv Clin Exp Med, don't hesitate to get in touch with our managing editor, Marek Misiak [[email protected]] – an online meeting with our statistical editors can be organized.

New statistical guidelines
https://advances.umw.edu.pl/en/ahead-of-print/206009/

Uniwersytet Medyczny im. Piastów Śląskich we Wrocławiu
Dr hab. Michał Czapla

📢 Our new manuscript withdrawal policy 📢✔️ Withdrawals initiated by authorsAuthors may withdraw their manuscript at any ...
06/09/2025

📢 Our new manuscript withdrawal policy 📢

✔️ Withdrawals initiated by authors
Authors may withdraw their manuscript at any stage of the editorial process. However, 2 conditions must be met for a withdrawal request to be processed:

– A clear and specific reason for withdrawal must be provided – both in the Editorial System and in the withdrawal statement.
– All authors must consent to the withdrawal. A statement signed by all authors should be scanned and submitted as a PDF file to the editorial office at [[email protected]] and/or uploaded to the Editorial System as an Additional File.

Until these conditions are fulfilled, the manuscript cannot be considered withdrawn.

Please note that if you intend to resubmit the manuscript, it is advisable to address necessary corrections during the initial verification or peer-review process rather than withdrawing the submission. A withdrawn and resubmitted manuscript is assessed as an entirely new submission – the previous (withdrawn) submission is not taken into consideration; in consequence, it prolongs the whole assessment process.

✔️ Withdrawals initiated by the editorial office
A manuscript will be withdrawn by the editorial office if:

– After acceptance, evidence for scientific misconduct is found
– Authors fail to sign the license agreement form within 30 days after acceptance
– Authors fail to pay the article processing charge (APC) within 30 days after acceptance
– Authors repeatedly fail to correct the galley proof or cease communication with the editorial office in this regard for more than 30 days.

✔️ Refund policy (withdrawals after the APC has already been paid)
Adv Clin Exp Med does not refund the APC once it has been paid. This policy applies in the following cases:
– When authors withdraw a manuscript after acceptance and payment of the APC (but before publication), regardless of the reason for withdrawal.
– When the manuscript is withdrawn by the editors due to the authors' failure to adequately correct errors or an attempt to change the authorship after acceptance (which violates our policy).
– When articles are retracted after publication due to author error or misconduct.
The APC is not a publication fee but an article-processing charge—it covers the costs of peer review, statistical review, editing, and typesetting. Since the majority of this work is completed before the APC is paid, refunds cannot be issued.
In exceptional cases, authors may appeal to the Editor-in-Chief, whose decision is final.

✔️ Withdrawal after acceptance due to funding limitations
We ask that authors submit papers to our journal only if they have funding. Before submitting, please make sure that you have the necessary funds to pay the APC in case of acceptance.
https://advances.umw.edu.pl/en/article-processing-charges/
Please note that our journal offers neither APC waivers nor discounts, including discounts for researchers from lower-income countries and countries against which international sanctions have been imposed.

✔️ Ethical considerations concerning withdrawals
Before you withdraw a paper, please consider that the editor and reviewers have likely already invested significant time reviewing your manuscript. The further along in the paper's peer-review process, the greater the ethical concern with withdrawing a manuscript, given that a considerable amount of time has been spent on the paper by reviewers, editors, and editorial assistants. Please let us know before withdrawing if there is anything we can do to avoid the withdrawal. We are happy to work with authors to remove any perceived barriers to publishing.
Please note that it is unethical and considered violating scientific norms (i.e., poor scientific practice bordering on scientific misconduct) to submit a paper still under consideration at a journal A to a different journal B. If you have already created a duplicate submission, please withdraw your paper from the other journal immediately and only submit it after receiving confirmation that your withdrawal request has been successfully processed. Otherwise, according to international best practices on publication ethics, a withdrawal may violate the research community's norms and may have negative consequences for the authors.

✔️ Withdrawing a published paper
Withdrawal is possible during the initial verification process, from the peer-review process or after acceptance, before publication. Withdrawing a paper after publication is called a retraction, please see https://advances.umw.edu.pl/en/appeals-complaints-corrections-retractions-commentaries for retraction policies.

📢Obesity Over the Life Span 📢📢 Call for submissions of an Expression of Interest for an Adv Clin Exp Med Special Collect...
05/09/2025

📢Obesity Over the Life Span 📢

📢 Call for submissions of an Expression of Interest for an Adv Clin Exp Med Special Collection on Obesity Over the Life Span 📢

This Special Issue of Advances in Clinical and Experimental Medicine will provide focused, comprehensive coverage of key clinical and public health issues related to obesity. Over the last three decades, the global prevalence of obesity has more than doubled, reflecting profound shifts in lifestyle, diet, and environmental determinants of health. Obesity has become the dominant form of malnutrition worldwide, contributing to a broad spectrum of health complications, including chronic diseases, functional impairments, and reduced quality of life.
This Special Issue aims to provide researchers and clinicians with an opportunity to publish original research, meta-analyses, and review articles addressing recent advances in the epidemiology, prevention, and treatment of obesity. Emphasis will be placed on multidisciplinary approaches, personalized management strategies, and the life-course perspective of this growing epidemic.

Topic and format
Advances in Clinical and Experimental Medicine is therefore seeking original papers for a Special Collection focused on the following themes:
• Global trends and epidemiology of obesity across all age groups.
• Prevention strategies targeting childhood, adolescent, and adult obesity.
• Innovative treatment approaches: lifestyle modifications, diet therapy, physical activity, pharmacotherapy, and bariatric surgery.
• Health complications of obesity and their management.
• Impact of obesity on public health systems and clinical practice.
• Multidisciplinary interventions.

MORE INFORMATION
https://advances.umw.edu.pl/en/obesity-lifespan

Izabella Uchmanowicz
Dr hab. Michał Czapla
Uniwersytet Medyczny im. Piastów Śląskich we Wrocławiu



🚀Ahead of print 🚀Caregivers’ perspectives on long-term cognitive, psychiatric, psychological, and social outcomes in NMD...
04/09/2025

🚀Ahead of print 🚀

Caregivers’ perspectives on long-term cognitive, psychiatric, psychological, and social outcomes in NMDAR encephalitis: Initial findings from the multi-center prospective SAPIENCE study

Highlights

• High caregiver distress in N-methyl-D-aspartate receptor (NMDAR) encephalitis: The SAPIENCE study uncovers significant psychological burden among caregivers of anti-NMDAR encephalitis patients.
• Diagnostic delays exacerbate caregiver strain: Frequent misdiagnoses highlight the critical need for early NMDAR encephalitis recognition in neurology and emergency settings.
• Structured psychological support boosts caregiver and patient outcomes: Implementing formal mental health services within integrated care models promotes long-term wellbeing.
• Multidisciplinary care enhances recovery and social reintegration: Coordinated teams – neurologists, psychiatrists, rehabilitation specialists, and social workers – drive improved quality of life for patients and their families.

https://advances.umw.edu.pl/en/ahead-of-print/207434/


Uniwersytet Medyczny im. Piastów Śląskich we Wrocławiu

ACEM monthly editorial duty hourOnce a month our Managing Editor, Marek Misiak, is awaiting you at a Google Meets meetin...
03/09/2025

ACEM monthly editorial duty hour

Once a month our Managing Editor, Marek Misiak, is awaiting you at a Google Meets meeting to answer all your questions and clarify problematic issues.

The meeting takes place on the first Thursday of each month between 9:30 and 10:30 CET. You can enter the meeting using the following URL:

meet.google.com/dqi-kzsz-fga

The only prerequisite is a Google account – without it you will not be able to log in into the meeting.

🗓️ Upcoming dates: July 3, August 7, September 4, October 2, November 6, December 4

Adres

Karola Marcinkowskiego 2-6
Wroclaw
50-368

Godziny Otwarcia

Poniedziałek 08:00 - 16:00
Wtorek 08:00 - 16:00
Środa 08:00 - 16:00
Czwartek 08:00 - 16:00
Piątek 08:00 - 16:00

Telefon

+48607983232

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