Advances in Clinical and Experimental Medicine

Advances in Clinical and Experimental Medicine 5-Year IF 2.0, IF 1.9, JCI (2024) 0.43, Scopus CiteScore 4.3, H-index 49 (SJR)
Initial editorial assessment and first decision within 24 h

📢1st Rare Disease Congress – Rare Diseases for Pediatricians and Family Physicians📢We cordially invite you to participat...
21/10/2025

📢1st Rare Disease Congress – Rare Diseases for Pediatricians and Family Physicians📢

We cordially invite you to participate in the 1st Rare Disease Congress - Rare Diseases for Pediatricians and Family Physicians, which will take place on November 21–22, 2025, at the Mercure Hotel in Wroclaw.

This is not a motto that has been defined: There is no disease whose incidence is so rare that it does not require our special attention.

Rare diseases pose a challenge to modern medicine, the healthcare system, and society as a whole. Although they are indeed rare, patients with rare diseases are numerous – in Poland, they may affect over 2.5–3 million people.

To date, nearly 8,000 conditions have been described that meet the definition of a rare disease (one person in 2,000 inhabitants). These diseases have a variety of symptoms, a progressive course, and often a poor prognosis. They encompass every field of medicine, so every doctor, nurse, physiotherapist, therapist, or other medical specialist undoubtedly encounters them in their practice. Early diagnosis and initiation of appropriate treatment are crucial.

Rare diseases, like all chronic diseases, require comprehensive and coordinated care. However, in medicine, pediatricians and family medicine physicians are closest to the patient with a rare disease. Therefore, to address the need to systematize and deepen knowledge about rare diseases, we invite you to the two-day First Congress of Rare Diseases, is organized by the Polish Society of Pediatric Endocrinology and Diabetology and the Polish Society of Congenital Metabolism, in cooperation with: the Polish Society of Human Genetics, the Polish Society of Pediatric Neurologists and the Polish Society of Family Medicine. The Congress will be a unique platform for exchanging knowledge, experiences, and the latest advancements in the field. The program includes thematic workshops and panel discussions. We believe that the opportunity for shared debate broadens diagnostic and therapeutic perspectives, building the potential and value of every physician.

This will also be an opportunity for our integration, which often creates new opportunities and opens doors in difficult clinical situations, improving the quality of life of patients suffering from rare diseases.

WE WARMLY INVITE YOU TO WROCLAW

MORE INFORMATION [IN POLISH]:

https://ptmr.info.pl/wydarzenia/i-kongres-chorob-rzadkich/

https://grupamedica.pl/wydarzenia/i-kongres-chorob-rzadkich-choroby-rzadkie-dla-pediatrow-i-lekarzy-rodzinnych-21-22-11-2025-hotel-mercure-wroclaw/

🚀Ahead of print🚀🚀Effects of echinacoside on the regulation of mitochondrial fission induced by TBK1/Drp1 in rheumatoid a...
20/10/2025

🚀Ahead of print🚀

🚀Effects of echinacoside on the regulation of mitochondrial fission induced by TBK1/Drp1 in rheumatoid arthritis🚀

Highlights

• TBK1 is highly expressed in rheumatoid arthritis (RA) synovial tissue and may promote inflammation through Drp1-mediated mitochondrial fission.
• Echinacoside reduces inflammation and oxidative stress in RA-derived MH7A synoviocytes, highlighting its potential as a natural anti-inflammatory compound.
• Echinacoside alleviates mitochondrial dysfunction by inhibiting mitochondrial fission in MH7A cells.
• The anti-inflammatory effects of echinacoside in rheumatoid arthritis are linked to its regulation of the TBK1/Drp1 signaling pathway.

https://advances.umw.edu.pl/en/ahead-of-print/199920/

If you experience problems in choosing a checklist, use this :-)To improve the success rate of publishing articles, auth...
19/10/2025

If you experience problems in choosing a checklist, use this :-)

To improve the success rate of publishing articles, authors can consider these checklists which will be considered as a checklist by the Reviewers in the review process.

Using a checklist can help you get published faster and maximize the impact of your work. The below checklists are copied from a tool was made by the EQUATOR Network in collaboration with Penelope.ai.

https://humangeneticsgenomics.ir/page/169/Checklists

📢Call for submissions of an Expression of Interest for an Adv Clin Exp Med Special Collection on Advances in Cardiovascu...
18/10/2025

📢Call for submissions of an Expression of Interest for an Adv Clin Exp Med Special Collection on Advances in Cardiovascular Care 📢

This Special Issue of the Advances in Clinical and Experimental Medicine will provide focused, comprehensive coverage of important clinical topics in cardiology. The issue will address selected clinical problems or conditions, including their pathophysiology, invasive and noninvasive diagnosis, drug therapy, surgical management, and rehabilitation.

This Special Issue aims to provide researchers with an opportunity to publish original research, meta-analyses and review articles related to recent advances in the cardiovascular field, with a particular focus on holistic and personalized management of patients with CVD.

Topic and format
Advances in Clinical and Experimental Medicine is therefore seeking original papers for a Special Collection focused on cardiovascular care.

MORE INFORMATION:

https://advances.umw.edu.pl/en/call-for-submissions-of-an-expression-of-interest-for-an-adv-clin-exp-med-special-collection-on-advances-in-cardiovascular-care


Izabella Uchmanowicz
Dr hab. Michał Czapla
Uniwersytet Medyczny im. Piastów Śląskich we Wrocławiu

🚀Ahead of print 🚀Eupatorin modulates BCPAP in thyroid cancer cell proliferation via suppressing the NF-κB/P13K/AKT signa...
17/10/2025

🚀Ahead of print 🚀

Eupatorin modulates BCPAP in thyroid cancer cell proliferation via suppressing the NF-κB/P13K/AKT signaling pathways

Highlights

– Eupatorin (EUP), a natural flavone compound, exhibits potent antiproliferative and pro-apoptotic effects on papillary thyroid cancer (PTC) cells by targeting key molecular pathways.
– EUP induces apoptosis in BCPAP cells through upregulation of caspase-9 and p53 expression and downregulation of proliferating cell nuclear antigen (PCNA).
– Inhibition of the PI3K/AKT and NF-κB signaling pathways plays a central role in EUP’s suppression of inflammation and thyroid cancer cell proliferation.
– These findings highlight Eupatorin as a promising natural therapeutic candidate for thyroid carcinoma by promoting apoptosis and reducing tumor growth via dual molecular pathway inhibition.

https://advances.umw.edu.pl/en/ahead-of-print/191595/

📚Publish in Advances in Clinical and Experimental Medicine! 📚💪 WHY?– We have a broad scope and publish papers from all f...
16/10/2025

📚Publish in Advances in Clinical and Experimental Medicine! 📚

💪 WHY?
– We have a broad scope and publish papers from all fields of medicine and related sciences;
– Our Impact Factor is 1.9 and steadily rising [see below];
– Our Scopus CiteScore is 4.3 and also steadily rising;
– We publish papers ahead of print [with active DOI] as soon as they are ready – no unnecessary waiting;
– We are indexed in all important databases;
– We offer professional linguistic editing and DTP;
– If you become our reviewer, article processing charge can be waivered.

🔎 HOW?
Create an account here:
https://www.editorialsystem.com/acem/preRegister/?email=
Check our instructions for authors here:
https://advances.umw.edu.pl/en/instructions-for-authors/
and submit your paper!

🔥 EDITORIALS
We invite experts to submit an editorial to our journal. Editorials published in our journal are meant to promote current and crucial directions of research in experimental and clinical medicine. Such article is published free of charge.
https://advances.umw.edu.pl/source/Flyer_ACEM_popr_2025-editorial.pdf

🔥 CALLS FOR SUBMISSION
Current calls for submissions in ACEM are listed below. Please share them with the members of your professional networks.
https://advances.umw.edu.pl/en/calls-for-submissions/

📢New call for submissions 📢📢 Innovations in Therapeutic Interventions: Advancing Clinical and Experimental Medicine 📢Han...
15/10/2025

📢New call for submissions 📢

📢 Innovations in Therapeutic Interventions: Advancing Clinical and Experimental Medicine 📢

Handling Editors

Dr. Masaru Tanaka (ELKH-SZTE Neuroscience Research Group, Eötvös Loránd Research Network, University of Szeged (ELKH-SZTE), Hungary)
Dr. Simone Battaglia (Center for Studies and Research in Cognitive Neuroscience, Department of Psychology, University of Bologna, Italy
Dr. Francesco Di Gregorio (AUSL Bologna; Department of Psychology, University of Bologna, Italy)
Prof. Izabella Uchmanowicz (Wroclaw Medical University, Poland)
Prof. Donata Kurpas (Wroclaw Medical University, Poland)

We welcome reviews as well as original research articles and research letters in various clinical and experimental medicine areas. We encourage submissions on the following topics:

Precision Medicine and Personalized Therapies: Explore novel approaches in tailoring medical treatments based on an individual's genetic makeup, environmental factors, and disease characteristics. Highlight the potential of precision medicine in improving patient outcomes and overcoming treatment challenges. This topic includes but is not limited to:

a) Immunotherapy and Immunomodulation: Investigate the role of immunotherapy and immunomodulation in treating various diseases, including cancer, autoimmune disorders, and infectious diseases. Focus on cutting-edge techniques, therapeutic targets and potential synergies with other treatment modalities.
b) Gene and Cell Therapies: Present innovative research on gene and cell-based therapies, such as stem cell transplantation, gene editing and regenerative medicine. Explore their applications across different diseases and discuss their clinical implications and prospects.

The paper can also encompass:
Artificial Intelligence and Big Data Analytics in Medicine: Examine the integration of artificial intelligence (AI) and big data analytics in medical research, diagnostics, treatment optimization, and patient care. Highlight the potential of AI algorithms, machine learning and data-driven approaches in revolutionizing healthcare practices.
Digital Health Technologies and Wearables: Discuss the advancements in digital health technologies (including telemedicine), wearable devices and remote monitoring systems. Explore their impact on healthcare delivery, patient engagement, disease management, and prevention strategies.

All papers should focus on:
Translational Research and Bench-to-Bedside Innovations: Showcase translational research efforts that bridge the gap between laboratory discoveries and clinical applications. Present successful examples of bench-to-bedside innovations that have improved patient care and outcomes.

Keywords
therapeutic interventions; personalized therapies; immunotherapy; immunomodulation; gene and cell therapies; artificial intelligence; Big Data analytics; digital health technologies

By submitting your research to Adv Clin Exp Med, you will become an integral part of a dynamic and vibrant community of dedicated researchers committed to advancing the fields of clinical and experimental medicine. By undergoing our rigorous peer-review process, you can be assured that only high-quality and impactful studies are published, enhancing your professional reputation and contributing to advancing medical knowledge.

We look forward to receiving your submissions and collaborating to make a lasting impact on the field of clinical and experimental medicine.

MORE INFORMATION
https://advances.umw.edu.pl/en/innovations

Uniwersytet Medyczny im. Piastów Śląskich we Wrocławiu

📢Obesity and out-of-hospital cardiac arrest (OHCA) – what's the real impact?📢A large European study, including researche...
14/10/2025

📢Obesity and out-of-hospital cardiac arrest (OHCA) – what's the real impact?📢

A large European study, including researchers from Wroclaw Medical University, analyzed data from more than 33,000 patients.
The findings challenge the so-called "obesity paradox." Obesity itself does not determine survival.

What really makes the difference?

⚡ Initial heart rhythm (VF/pVT = higher survival chances)
📍 Place of arrest (public setting = faster help, AED access)
⏳ Age and chronic conditions

Women often face OHCA in worse circumstances (at home, without witnesses, with more comorbidities). But when help arrives on time, their chances of return of spontaneous circulation (ROSC) are comparable – and sometimes even higher – than men's.

➡️ This shows why sex-specific factors must be considered in both research and clinical practice.

📖 Read the full article in Advances in Clinical and Experimental Medicine: https://advances.umw.edu.pl/en/ahead-of-print/193367/

🎧 Listen to the podcast: https://soundcloud.com/wmu-pl/obesity-and-cardiac-arrest-differences-between-women-and-men?utm_source=clipboard&utm_medium=text&utm_campaign=social_sharing&si=ad6c4b47f26f4d23ac6ebff7fd32f3bb

📢From Bench to Bedside: Advances in Neuroinflammation and CNS Disorder Research 📢📢 Call for submissions of an Expression...
14/10/2025

📢From Bench to Bedside: Advances in Neuroinflammation and CNS Disorder Research 📢

📢 Call for submissions of an Expression of Interest for an Adv Clin Exp Med Special Collection on Neuroinflammation in CNS Disorders 📢

The editors of this special collection invite submissions exploring the latest advances in clinical and experimental research on neuroinflammation in the central nervous system (CNS). Neuroinflammation is at the forefront of neuroscience, shaping our understanding of CNS disorders such as neurodegenerative disease, psychiatric disorders, and traumatic brain injuries. This collection aims to unite diverse perspectives, fostering insights into the complex cellular and molecular mechanisms driving neuroinflammatory processes. We encourage the submission of original research, meta-analyses, and comprehensive review articles that shed light on diagnostic, therapeutic, and mechanistic aspects of CNS inflammation.
We are particularly interested in manuscripts that explore the interplay between immune cells, neurons, and glia, with a focus on translational research. Contributions detailing innovative diagnostic approaches, therapeutic targets, or computational models are highly welcome. Join this effort to advance the boundaries of neuroinflammation research and contribute to groundbreaking findings that bridge laboratory and clinical neuroscience.

Topic and format
Advances in Clinical and Experimental Medicine is therefore seeking original papers for a Special Collection focused on the following themes:
• Neuroimmune Interactions in Health and Disease
• Cellular and Molecular Pathways of Neuroinflammation
• Neuroinflammation and Neurodegeneration: Cause or Consequence?
• Innovative Imaging and Biomarkers for CNS Inflammation
• Therapeutic Interventions Targeting Neuroinflammation
• Role of Microglia and Astrocytes in Neuroinflammatory Diseases

MORE INFORMATION
https://advances.umw.edu.pl/en/neuroinflammation-in-cns-disorders



Masaru Tanaka

🚀Ahead of print🚀Transcranial direct current stimulation (tDCS): A new, (still) legal form of “neurodoping” in sports?Hig...
13/10/2025

🚀Ahead of print🚀

Transcranial direct current stimulation (tDCS): A new, (still) legal form of “neurodoping” in sports?

Highlights

• Transcranial direct current stimulation (tDCS) shows small, inconsistent performance gains with big individual differences.
• Short-term safety of tDCS is good; long-term and DIY misuse remain concerns.
• Use of tDCS is effectively undetectable, making enforcement difficult.
• tDCS likely meets World Anti-Doping Agency (WADA) “enhancement” and “spirit” criteria but not health risk; a ban is premature.
• Recommended: monitor, issue guidance, require disclosure, and fund targeted research.

https://advances.umw.edu.pl/en/ahead-of-print/211178/

📢¡Únete al movimiento para avanzar en la salud mental y el bienestar!📢Advances in Clinical and Experimental Medicine te ...
12/10/2025

📢¡Únete al movimiento para avanzar en la salud mental y el bienestar!📢

Advances in Clinical and Experimental Medicine te invita a enviar tu investigación y artículos de vanguardia en el campo de la salud mental y el bienestar. Buscamos contribuciones innovadoras que amplíen los límites de la comprensión, el tratamiento y la promoción del bienestar mental.

Editores a cargo

Prof. Dr. Raúl Juárez-Vela (Grupo de Investigación en Cuidados (GRUPAC), Facultad de Ciencias de la Salud, Universidad de La Rioja, Logroño, España; ORCID 0000-0003-3597-2048) [email protected]

Los temas de interés incluyen, pero no se limitan a:

- Intervenciones terapéuticas innovadoras
- Estrategias para la prevención y promoción del bienestar mental
- Impacto de la salud mental en la calidad de vida
- Nuevos enfoques en el tratamiento de trastornos mentales
- Estudios sobre la relación entre la salud mental y las enfermedades físicas

¿Por qué publicar con nosotros?

- Visibilidad global: Alcanza una amplia audiencia internacional con tu trabajo.
- Revisión rigurosa: Benefíciate de nuestro proceso de revisión por pares de alta calidad.
- Impacto académico: Haz una contribución significativa a un campo vital y dinámico.

Proceso de envío

Como primer paso, solicitamos el envío de una Expresión de Interés con un resumen de artículos originales que aborden los temas mencionados al Editor de Sección de Adv Clin Exp Med: [email protected]

El Editor de Sección, junto con el Editor en Jefe, revisará todas las presentaciones y seleccionará aquellas que serán invitadas a enviar un artículo completo. El proceso de envío seguirá el proceso en línea regular de Adv Clin Exp Med. Todos los manuscritos serán enviados a al menos dos revisores independientes.

Fechas y tarifas

- Envío de la Expresión de Interés hasta el 31 de diciembre de 2025 a [email protected]
- Invitación para enviar un artículo completo antes del 31 de enero de 2026;
- Envío del artículo completo antes del 31 de marzo de 2026.

Si se acepta, los autores deberán pagar una tarifa (https://advances.umw.edu.pl/en/article-processing-charges/) para cubrir los costos de publicación;

Para autores seleccionados (expertos destacados), es posible reducir o incluso cancelar la tarifa de publicación.

Envía tu manuscrito hoy y únete a la conversación global sobre el mejoramiento de la salud mental y el bienestar. Para más detalles sobre el proceso de envío, visita nuestro sitio web.

¡Esperamos con ansias tus valiosas contribuciones!

📢New call for submissions📢📢Join the Movement to Advance Mental Health and Wellbeing!📢Advances in Clinical and Experiment...
12/10/2025

📢New call for submissions📢

📢Join the Movement to Advance Mental Health and Wellbeing!📢

Advances in Clinical and Experimental Medicine invites you to submit your cutting-edge research and articles in the field of Mental Health and Well-being. We are seeking groundbreaking contributions that push the boundaries of understanding, treating, and promoting mental wellbeing.

Handling Editors

Prof. Raúl Juárez-Vela (Group of Research in Care (GRUPAC), Faculty of Health Sciences, University of La Rioja, Logroño, Spain; ORCID 0000-0003-3597-2048) [email protected]

Topics of interest include, but are not limited to:

Innovative therapeutic interventions
Strategies for prevention and promotion of mental wellbeing
Impact of mental health on quality of life
New approaches in the treatment of mental disorders
Studies on the relationship between mental health and physical diseases

Why publish with us?

Global Visibility: Reach a wide international audience with your work
Rigorous Review: Benefit from our high-quality peer review process
Academic Impact: Make a significant contribution to a vital and dynamic field

Submission process

As a first step, we ask for submissions of an Expression of Interest with an Abstract of original papers outlining the themes above to Adv Clin Exp Med Section Editor: [email protected]

The Section Editor, jointly with the Editor-in-Chief, will review all submissions and select those who will be invited to submit a full paper. The submission process will then follow the regular Adv Clin Exp Med. online process. All manuscripts will be sent to at least two independent reviewers.

Dates and fees

Submission of Expression of Interest until December 31, 2025, to [email protected]
Invitation to submit a full paper by January 31, 2026;
Submission of full paper by March 31, 2026.
If accepted, Authors will be required to pay a fee (https://advances.umw.edu.pl/en/article-processing-charges/) to cover publication costs;

For selected Authors (outstanding experts), it is possible to reduce or even cancel the publication fee.

Submit your manuscript today and join the global conversation on enhancing mental health and well-being. For more details on the submission process, visit our website.

We eagerly anticipate your valuable contributions!

Adres

Karola Marcinkowskiego 2-6
Wroclaw
50-368

Godziny Otwarcia

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Telefon

+48607983232

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