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Advances in Clinical and Experimental Medicine

Strona główna
Polska
Wroclaw
Advances in Clinical and Experimental Medicine

5-Year IF 2.0, IF 1.9, JCI (2024) 0.43, Scopus CiteScore 4.3, H-index 49 (SJR)
Initial editorial assessment and first decision within 24 h

04/01/2026

📢Out in Health: Health Equity and Innovations in LGBT+ Care📢

Call for submissions of an Expression of Interest for an Adv Clin Exp Med Special Collection on LGBT+ Health Equity and Innovation

Handling Editors

Assoc. Prof. Michał Czapla (Division of Scientific Research and Innovation in Emergency Medical Service, Department of Emergency Medical Service, Faculty of Nursing and Midwifery, Wroclaw Medical University, Wrocław, Poland; Group of Research in Care (GRUPAC), Faculty of Health Sciences, University of La Rioja, Logroño, Spain; ORCID 0000-0002-4245-5420) [email protected]

Dr. Anthony Dissen (Stockton University, Galloway, USA; ORCID 0000-0003-0828-387X) [email protected]

This Call for Submissions invites Expressions of Interest for a Special Collection of Advances in Clinical and Experimental Medicine, focusing on LGBT+ health equity and innovation.

LGBT+ individuals around the world face unique and persistent health disparities driven by stigma, discrimination, and systemic exclusion from healthcare systems. These inequities result in significantly worse physical and mental health outcomes and limit access to inclusive, culturally competent care.

This Special Collection will offer researchers and clinicians an opportunity to publish original research, meta-analyses, and review articles that address these disparities and propose inclusive, personalized, and innovative solutions to improve health outcomes for LGBT+ populations.

This Call welcomes submissions on (but not limited to):

* Mental Health & Well-being
* Sexual & Reproductive Health
* Transgender & Gender-Diverse Health
* Equity in Healthcare Access
* Social Determinants of Health
* Stigma & Healthcare Avoidance
* Community & Public Health Initiatives
* Intersectionality in Health

MORE INFORMATION
https://advances.umw.edu.pl/en/lgbt

Uniwersytet Medyczny im. Piastów Śląskich we Wrocławiu
Dr hab. Michał Czapla

03/01/2026

📢Obesity Over the Life Span 📢

📢 Call for submissions of an Expression of Interest for an Adv Clin Exp Med Special Collection on Obesity Over the Life Span 📢

This Special Issue of Advances in Clinical and Experimental Medicine will provide focused, comprehensive coverage of key clinical and public health issues related to obesity. Over the last three decades, the global prevalence of obesity has more than doubled, reflecting profound shifts in lifestyle, diet, and environmental determinants of health. Obesity has become the dominant form of malnutrition worldwide, contributing to a broad spectrum of health complications, including chronic diseases, functional impairments, and reduced quality of life.
This Special Issue aims to provide researchers and clinicians with an opportunity to publish original research, meta-analyses, and review articles addressing recent advances in the epidemiology, prevention, and treatment of obesity. Emphasis will be placed on multidisciplinary approaches, personalized management strategies, and the life-course perspective of this growing epidemic.

Topic and format
Advances in Clinical and Experimental Medicine is therefore seeking original papers for a Special Collection focused on the following themes:
• Global trends and epidemiology of obesity across all age groups.
• Prevention strategies targeting childhood, adolescent, and adult obesity.
• Innovative treatment approaches: lifestyle modifications, diet therapy, physical activity, pharmacotherapy, and bariatric surgery.
• Health complications of obesity and their management.
• Impact of obesity on public health systems and clinical practice.
• Multidisciplinary interventions.

MORE INFORMATION
https://advances.umw.edu.pl/en/obesity-lifespan

Izabella Uchmanowicz
Dr hab. Michał Czapla
Uniwersytet Medyczny im. Piastów Śląskich we Wrocławiu

02/01/2026

📚Publish in Advances in Clinical and Experimental Medicine! 📚

💪 WHY?
– We have a broad scope and publish papers from all fields of medicine and related sciences;
– Our Impact Factor is 1.9 and steadily rising [see below];
– Our Scopus CiteScore is 4.3 and also steadily rising;
– We publish papers ahead of print [with active DOI] as soon as they are ready – no unnecessary waiting;
– We are indexed in all important databases;
– We offer professional linguistic editing and DTP;
– If you become our reviewer, article processing charge can be waivered.

🔎 HOW?
Create an account here:
https://www.editorialsystem.com/acem/preRegister/?email=
Check our instructions for authors here:
https://advances.umw.edu.pl/en/instructions-for-authors/
and submit your paper!

🔥 EDITORIALS
We invite experts to submit an editorial to our journal. Editorials published in our journal are meant to promote current and crucial directions of research in experimental and clinical medicine. Such article is published free of charge.
https://ojs.umw.edu.pl/files/acem/Flyer_ACEM_popr_2025-editorial%20(9)-1.pdf

🔥 CALLS FOR SUBMISSION
Current calls for submissions in ACEM are listed below. Please share them with the members of your professional networks.
https://advances.umw.edu.pl/en/calls-for-submissions/

02/01/2026

🚀Ahead of print 🚀

The diagnostic performance of shear-wave elastography combined with ultrasound and magnetic resonance imaging in breast lesions: A single center retrospective study

Highlights

➡️Advanced breast imaging with shear-wave elastography (SWE): Combining SWE with conventional ultrasound and MRI provides a state-of-the-art, triple-modality breast imaging strategy for superior diagnostic confidence.
➡️Shear-wave elastography leads in diagnostic precision: SWE offers higher specificity (65.6%) and a significantly improved positive predictive value (PPV = 50%) compared to traditional ultrasound and MRI alone.
➡️Unmatched accuracy in breast lesion diagnosis: Integrating ultrasound, SWE and MRI achieves an impressive 90.9% overall diagnostic accuracy, setting a new standard in breast cancer screening.
➡️Enhanced sensitivity and specificity with multimodal imaging: This combined workflow boosts sensitivity to 94.3% and specificity to 89.1%, reducing both false positives and false negatives.
➡️Early detection and better outcomes: Incorporating SWE into routine breast imaging can accelerate early breast cancer detection, leading to improved patient outcomes and more efficient care pathways.

https://advances.umw.edu.pl/en/ahead-of-print/203584/

01/01/2026

Boulevard Saint Denis in Argenteuil im Winter (1875); Claude Monet (1840-1926); Museum of Fine Arts, Boston, USA

31/12/2025

Ravi Shankar
Snowfall

Particulate as ash, new year's first snow falls
upon peaked roofs, car hoods, undulant hills,
in imitation of motion that moves the way

static cascades down screens when the cable
zaps out, persistent & granular with a flicker
of legibility that dissipates before it can be

interpolated into any succession of imagery.
One hour stretches sixty minutes into a field
of white flurry: hexagonal lattices of water

molecules that accumulate in drifts too soon
strewn with sand, hewn into browning
mounds by plow blade, left to turn to slush.

[Source: Ravi Shankar, Deepening Groove, The National Poetry Review; Orono, USA; 2011]

[Illustration: Winter (1890); Ivan Shishkin (1832-1898); State Russian Museum, Saint Petersburg, Russia]

30/12/2025

🚀Ahead of print🚀

Matrix metalloproteinases and tissue inhibitors of metalloproteinases as potential biomarkers for pulmonary arterial hypertension: A review

Highlights

➡️Late-stage pulmonary arterial hypertension (PAH) diagnosis delays treatment: Nonspecific symptoms often result in advanced disease at presentation, worsening prognosis.
➡️Matrix metalloproteinases (MMPs) and tissue inhibitors (TIMPs) as PAH biomarkers: Emerging evidence positions MMP/TIMP profiling for early detection and prognostic assessment.
➡️MMP-2, MMP-7 and MMP-9 show the strongest prognostic value in PAH: These specific MMPs outperform others in predicting disease progression and patient outcomes.
➡️Significant biomarker concentration differences distinguish PAH from other pulmonary hypertension types: Multiple studies confirm diagnostic specificity for MMP/TIMP levels.
➡️Prospective studies are crucial to validate MMP/TIMP profiling in PAH: Ongoing research aims to integrate these biomarkers into clinical diagnostic and prognostic workflows.

https://advances.umw.edu.pl/en/ahead-of-print/204831/

30/12/2025

🚀Ahead of print 🚀

Immunogenic mutanome of breast cancer: Advances, challenges and future directions in neoantigen-based immunotherapy

Highlights

• Tumor heterogeneity, mutational burden and immune modulation dictate neoantigen immunogenicity, steering both treatment success and immune escape in breast cancer.
• Neoantigen vaccines and adoptive T cell therapies show promise but must overcome antigen loss and intratumoral diversity to achieve durable responses.
• Dual-strategy treatments that pair neoantigen targeting with checkpoint inhibitors amplify antitumor immunity, offering a path to stronger, more consistent clinical outcomes.

https://advances.umw.edu.pl/en/ahead-of-print/205014/

29/12/2025

🚀Ahead of print🚀

Preoperative hemoglobin A1c as a predictor of lymph node metastasis in diabetic women with endometrial cancer

Highlights

➡️Preoperative HbA1c levels were evaluated as a predictor of lymph node metastasis in diabetic women with endometrial
carcinoma.
➡️Higher HbA1c levels were associated with an increased risk of lymph node metastasis.
➡️The study highlights the potential role of glycemic control in endometrial cancer progression.
➡️HbA1c may serve as a useful biomarker for risk stratification in diabetic women with endometrial carcinoma.
➡️Findings suggest integrating HbA1c assessment into preoperative evaluations for better clinical decision-making.

https://advances.umw.edu.pl/en/ahead-of-print/198152/

29/12/2025

🚀Ahead of print 🚀

RNA binding protein ELAVL1 is associated with severity and prognosis of hepatocellular carcinoma patients: A retrospective study

➡️ELAVL1 Identified as a Prognostic Biomarker in Hepatocellular Carcinoma. Elevated serum ELAVL1 levels were strongly associated with advanced TNM and BCLC stages, lymphatic metastasis, and poor patient outcomes.

➡️High ELAVL1 Expression Predicts Mortality and Recurrence in HCC Patients. ROC curve analysis showed ELAVL1 had strong predictive value for mortality (AUC = 0.818) and recurrence (AUC = 0.732).

➡️Correlation Between ELAVL1 and Established HCC Biomarkers. ELAVL1 levels were positively correlated with alpha-fetoprotein (AFP) and carcinoembryonic antigen (CEA), reinforcing its role in disease progression.

➡️Independent Risk Factors for Poor HCC Prognosis Include ELAVL1. Higher BCLC stage, lymphatic metastasis, age, AFP, and ELAVL1 were identified as independent predictors of adverse outcomes.

https://advances.umw.edu.pl/en/ahead-of-print/195187/

28/12/2025

NEW REQUIREMENTS CONCERNING FIGURES IN ADV CLIN EXP MED

We implemented new requirements regarding figures – they stem from stipulations issued by databases and digital archives in which our journal is indexed.

We accept up to 10 figures (2 figures in Research letters). Overtly complex figures will be divided into smaller ones and the number of figures will be counted again. A single figure can have no more than 6 panels (A–F). One panel means one chart – multiple small charts cannot form one panel.

All elements of each figure must be legible when viewed on an A4 page in a PDF file in full-screen mode, without zooming. Overtly complex figures with multiple charts/graphs combined into one panel cannot fulfill this requirement. Figures of low quality cannot be published, and consequently, papers with low-quality figures will not be published, even if accepted by peer reviewers.

Figures should be placed in separate files, not pasted into the main body of the text. Name your figure files with "Fig" and the figure number, e.g., Fig.1.tiff.

References to Figures should be placed according to the sequence of citing them in the manuscript. The text should include references to all figures.

Each figure should have a concise, self-explanatory caption describing accurately what the figure depicts. Captions for the figures should be placed at the end of the main body of the text. Do not embed the legend in the figure file. When applicable, be sure that both the figure captions and the figures themselves contain corresponding labels for multiple parts. Identify all elements found in the figure in the figure caption; and use boxes, circles, etc., as coordinate points in graphs. If any magnification is used in the photographs, indicate this by using scale bars within the figures themselves. All abbreviations used in a given table/figure should be explained below it or in the caption, even if a given abbreviation has already been explained in the text.

If Authors used in the work any figures, photographs, charts, tables, etc. which are not their work, and are protected by the copyright law, they shall be obliged to provide the Publisher with a written authorization to use such materials issued by the author’s economic rights holders. Identify previously published material by giving the original source in the form of a reference citation at the end of the figure caption.

OUR NEW TECHNICAL REQUIREMENTS:

https://advances.umw.edu.pl/source/Adv%20Clin%20Exp%20Med-figures-technical%20requirements.pdf

27/12/2025

📢Call for submissions of an Expression of Interest for an Adv Clin Exp Med Special Collection on

Application of stem cells in human medicine – from basic science research to clinical trials 📢

Medicine in the twenty-first century is closely associated with stem cell research, based on advanced in vitro analyzes, the use of model animals, and their application in clinical trials. Experimental research requires understanding the physiological and morphological properties of stem cells and analyzing their ability to divide and differentiate into other cell types. The best-known stem cells are those derived from bone marrow and umbilical cord blood. However, in recent years, stem cells have been discovered in, for example, adipose tissue and Wharton jelly. Stem cells isolated from these tissues, once properly differentiated, are increasingly used for the treatment of bone and neurodegenerative diseases. In recent years, the number of therapies using stem cells has increased significantly. The ability of stem cells to differentiate makes them an increasingly common therapeutic tool in regenerative and reconstructive medicine.

Key words:

mesenchymal stem cells, embryonic stem cells, iPSCs, cancer stem cells, cell proliferation and differentiation, small extracellular vesicles, exosomes, omics, animal models, preclinical and clinical trials, regenerative medicine, reconstructive medicine

Articles submitted should be related to the topic of stem cells and their use in basic and clinical research. Topics may include:

• molecular research involving advanced genomic methods
• tissue and cell research
• studies on the morphological and physiological properties of stem cells
• studies on the proliferative and multidirectional differentiation capacity of stem cells
• studies on model animals
• use of stem cells in preclinical and clinical research
• therapies with stem cell
• stem cells in regenerative and reconstructive medicine
• stem cells in translational medicine

Review articles describing recent achievements in stem cell medicine, as well as original articles will be accepted.

MORE INFORMATION:

https://advances.umw.edu.pl/en/application-stem

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Karola Marcinkowskiego 2-6
Wroclaw
50-368

Godziny Otwarcia

Poniedziałek	08:00 - 16:00
Wtorek	08:00 - 16:00
Środa	08:00 - 16:00
Czwartek	08:00 - 16:00
Piątek	08:00 - 16:00

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+48607983232

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