23/12/2024
Towana Looney is the fifth American given a gene-edited pig organ — and notably, she isn’t as sick as prior recipients who died within two months of receiving a pig kidney or heart.
“It’s like a new beginning,” Looney, 53, told The Associated Press. Right away, “the energy I had was amazing. To have a working kidney — and to feel it — is unbelievable.”
Looney’s surgery marks an important step as scientists get ready for formal studies of xenotransplantation expected to begin next year, said Dr. Robert Montgomery of NYU Langone Health, who led the highly experimental procedure.
Looney is recuperating well after her transplant, which was announced Tuesday. She was discharged from the hospital just 11 days after surgery to continue recovery in a nearby apartment although temporarily readmitted this week while her medications are adjusted. Doctors expect her to return home to Alabama in three months. If the pig kidney were to fail, she could begin dialysis again.
Looney donated a kidney to her mother in 1999. Later a complication during pregnancy caused high blood pressure that damaged her remaining kidney, which eventually failed. It’s incredibly rare for living donors to develop kidney failure although those who do are given extra priority on the transplant list.
Looney was initially discharged on Dec. 6, wearing monitors to track her blood pressure, heart rate and other bodily functions and returning to the hospital for daily checkups before her medication readmission. Doctors scrutinize her bloodwork and other tests, comparing them to prior research in animals and a few humans in hopes of spotting an early warning if problems crop up. | via Associated Press
