JAMA Ophthalmology

28/09/2024

Biallelic pathogenic variants in UBAP1L were identified in six probands with retinal dystrophies, establishing UBAP1L as a disease gene for inherited retinal diseases in humans. https://ja.ma/3BmVszf

28/09/2024

Most viewed in the last 7 days from JAMA Ophthalmology: This Viewpoint discusses vision impairment as a modifiable dementia risk factor.

https://ja.ma/3XAdUf6

27/09/2024

This investigation provides evidence that pathogenic variants in METTL23 are associated with normal-tension glaucoma. https://ja.ma/4dgUTEg

26/09/2024

Artificial intelligence models for myopic maculopathy classification and segmentation, validated on a public dataset, demonstrated diagnostic performance comparable to or exceeding that of ophthalmologists. https://ja.ma/47DAW9m

25/09/2024

This case report investigates why a female astronaut presented with more severe symptoms of spaceflight-associated neuro-ocular syndrome than previous astronauts of either s*x. https://ja.ma/3Bi17GL

24/09/2024

Most viewed in the last 7 days from JAMA Ophthalmology: A 61-year-old woman with no medical history presented with bilateral blurry vision a few days after dyeing her hair with hair dye containing aromatic amines.

https://ja.ma/3TA1BOC

24/09/2024

In this quality improvement study, a retrieval-augmented LLM framework was developed that achieved capabilities for human ranking scores or inappropriate content not different from a commercially available LLM. https://ja.ma/4ewpi2h

23/09/2024

Filgotinib lowered the risk of treatment failure in participants with active noninfectious intermediate uveitis, posterior uveitis, or panuveitis vs placebo.

https://ja.ma/4dhW5ay

22/09/2024

Viewpoint discusses vision impairment as a modifiable dementia risk factor.

https://ja.ma/3zivhJp

21/09/2024

While many in US rely on Federally Qualified Health Centers (FQHCs) for healthcare, only 8.9% of Florida's FQHC sites offer eye care, highlighting gap in eye care needs for underserved communities. https://ja.ma/4gte54v

21/09/2024

Most viewed in the last 7 days from JAMA Ophthalmology: A 61-year-old woman with no medical history presented with bilateral blurry vision a few days after dyeing her hair with hair dye containing aromatic amines.

https://ja.ma/3XuzTnL

20/09/2024

Listen to an interview with Byron L. Lam, MD, author of "Detection and Referral of Depression in Patients With Visual Impairment: A Call for Practical Training and Methods," with Neil M. Bressler, MD.

Interview with Byron L. Lam, MD, author of Detection and Referral of Depression in Patients With Visual Impairment: A Call for Practical Training and Methods. Hosted by Neil M. Bressler, MD.

In the US, you can call, text, or chat 988, the Su***de and Crisis Lifeline.

19/09/2024

Nationwide cohort study in Korea finds 18% cumulative incidence of depressive disorders over 10 years in patients with retinitis pigmentosa (RP). The risk of developing depression peaks in those diagnosed in their 20s and 60s. https://ja.ma/4eto4F3

18/09/2024

Postoperative endophthalmitis incidence after cataract surgery was comparable when using 1% povidone iodine disinfection w/ selective antibiotic prophylaxis vs antibiotic prophylaxis use in 37 reported studies. https://ja.ma/3B6rnUh

17/09/2024

Most viewed in the last 7 days from JAMA Ophthalmology: What proportion of dementia cases in the US is potentially attributable to objectively measured vision impairments?

https://ja.ma/4e7DYW8

17/09/2024

Viewpoint highlights the discrepancy between dosing and patient assessment schedules in clinical trials for 2 new intravitreal agents, faricimab, 6 mg, and aflibercept, 8 mg, to treat neovascular AMD. https://ja.ma/4gFWVRt

16/09/2024

Case report describes a diagnosis of streaky multifocal choroiditis in a boy who presented with distorted vision in his left eye for 3 years.

https://ja.ma/47tGoM6

14/09/2024

Case report describes a woman who presented with bilateral blurry vision a few days after dyeing her hair with hair dye containing aromatic amines.

https://ja.ma/3TuFJnI

14/09/2024

This cohort study found that factors such as rural residence, preexisting diabetic retinopathy in Black patients, and Hispanic ethnicity were associated with lower odds of receiving guideline-compliant eye care. https://ja.ma/3XILAIT

14/09/2024

Most viewed in the last 7 days from JAMA Ophthalmology: What proportion of dementia cases in the US is potentially attributable to objectively measured vision impairments?

https://ja.ma/3ZmVhOc

11/09/2024

More than two-thirds of commercially insured children with conjunctivitis filled a prescription for topical antibiotics within 1 day of an ambulatory care visit. Revisits and new antibiotic dispensations were rare.

https://ja.ma/4dh5Wxr

10/09/2024

73 yr old man presented with a 5-day history of a fast-growing right eyebrow nodule with raised borders and central ulceration. There was no discomfort, and the patient denied vision changes. Lesion was refractory to treatment. What would you do next?

https://ja.ma/3B73cF8

10/09/2024

Most viewed in the last 7 days from JAMA Ophthalmology: How do outcomes differ for PDR treated with panretinal photocoagulation (PRP) first, then anti–vascular endothelial growth factor (VEGF), compared with anti-VEGF treatment first, followed by PRP?

https://ja.ma/47e09qI

09/09/2024

Post hoc analysis of data from 2 RCTs found low rates of clinically relevant intraocular pressure-related events after 1 year of intravitreous injections of lampalizumab, 0.1 mL. Results may be valuable in the design of future therapeutic trials. https://ja.ma/4ehc35L

07/09/2024

Correlation between proximal location of disc hemorrhage and glaucoma progression emphasizes higher risk in cup-type hemorrhage, suggesting disc hemorrhage proximity as a potential predictor for progression.

https://ja.ma/3XyoBzY