JAMA Ophthalmology

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JAMA Ophthalmology JAMA Ophthalmology is a member of the JAMA Network, a consortium of peer-reviewed publications.

Case report: Oral tofacitinib achieved rapid and sustained remission in cases of refractory thyroid eye disease, targeti...
31/10/2025

Case report: Oral tofacitinib achieved rapid and sustained remission in cases of refractory thyroid eye disease, targeting proinflammatory cytokine pathways implicated in orbital fibroblast activation. https://ja.ma/47rc4BY

Interview with Noemi Lois, MD, PhD, author of Retinal Sensitivity and Retinal Perfusion in Diabetic Retinopathy. Hosted ...
30/10/2025

Interview with Noemi Lois, MD, PhD, author of Retinal Sensitivity and Retinal Perfusion in Diabetic Retinopathy. Hosted by Neil Bressler, MD.

Retinal capillary nonperfusion produces greater sensitivity deficits in people with diabetic retinopathy, but one-third ...
30/10/2025

Retinal capillary nonperfusion produces greater sensitivity deficits in people with diabetic retinopathy, but one-third of perfused areas also show reduced function.

Sensitivity deficit worsened by approximately 45% in the first year, even in the context of poor glycemic control and advanced disease. https://ja.ma/43EXKop

RCT: Low-level red-light therapy for   control slows axial elongation and refractive change, with some participants show...
29/10/2025

RCT: Low-level red-light therapy for control slows axial elongation and refractive change, with some participants showing temporary retinal changes on OCT which resolved without affecting vision. https://ja.ma/4nnXhhC

Smooth pursuit eye movement velocity in Division I American football players was not affected by repetitive head impacts...
28/10/2025

Smooth pursuit eye movement velocity in Division I American football players was not affected by repetitive head impacts during a single season. https://ja.ma/4oYITh9

While the incidence of ocular complications was higher in myopic children compared to nonmyopic ones, atropine use for  ...
27/10/2025

While the incidence of ocular complications was higher in myopic children compared to nonmyopic ones, atropine use for control was not associated with these risks. https://ja.ma/47lrlnR

Advanced multimodal imaging indicates that vision loss in AZOOR initiates at the level of phototransduction within photo...
26/10/2025

Advanced multimodal imaging indicates that vision loss in AZOOR initiates at the level of phototransduction within photoreceptor outer segments.

Optoretinography and adaptive optics microperimetry reveal abnormal cone elongation in areas of absolute scotoma. https://ja.ma/3WkFD3e

Metformin use is not significantly associated with the development or progression of age-related macular degeneration (A...
26/10/2025

Metformin use is not significantly associated with the development or progression of age-related macular degeneration (AMD), suggesting similar risks of AMD and its progression between those prescribed metformin and those not. https://ja.ma/4oyVuqQ

 -1RA use was associated with reduced risk of developing nonexudative AMD but was not associated with progression to exu...
25/10/2025

-1RA use was associated with reduced risk of developing nonexudative AMD but was not associated with progression to exudative AMD among individuals with nonexudative AMD.

https://ja.ma/3JrPzoI

Among people with type 2 diabetes, risk of retinopathy onset increased with higher HbA1C and frequent nonsevere hypoglyc...
24/10/2025

Among people with type 2 diabetes, risk of retinopathy onset increased with higher HbA1C and frequent nonsevere hypoglycemia. https://ja.ma/47DPMyj

Apixaban, paclitaxel, ibrutinib, and sildenafil use is associated with elevated rates of maculopathy, with incidence est...
23/10/2025

Apixaban, paclitaxel, ibrutinib, and sildenafil use is associated with elevated rates of maculopathy, with incidence estimates up to 15.7% and dose-dependent risk for some agents.

https://ja.ma/3WVFOlC

DeepSeek-R1 demonstrated superior performance compared to OpenAI o1 in clinical diagnosis and management across subspeci...
22/10/2025

DeepSeek-R1 demonstrated superior performance compared to OpenAI o1 in clinical diagnosis and management across subspecialties, while also reducing operating costs.

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