JAMA Ophthalmology

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JAMA Ophthalmology JAMA Ophthalmology is a member of the JAMA Network, a consortium of peer-reviewed publications.

Faricimab, a VEGF and angiopoietin-2 inhibitor, generally shows efficacy and safety in treating diabetic macular edema a...
24/01/2025

Faricimab, a VEGF and angiopoietin-2 inhibitor, generally shows efficacy and safety in treating diabetic macular edema and neovascular age-related macular degeneration.

https://ja.ma/4gezKMi

Viewpoint examines results from the LIGHTSIDE trials for photobiomodulation to treat age-related macular degeneration an...
24/01/2025

Viewpoint examines results from the LIGHTSIDE trials for photobiomodulation to treat age-related macular degeneration and raises questions regarding the trial protocols and the efficacy and safety of the therapy.

https://ja.ma/42q5bQE

RCT: Femtosecond laser arcuate keratotomy was not superior to Toric IOL implantation for correcting astigmatism in patie...
23/01/2025

RCT: Femtosecond laser arcuate keratotomy was not superior to Toric IOL implantation for correcting astigmatism in patients with mild-to-moderate astigmatism undergoing femtosecond laser-assisted cataract surgery.

https://ja.ma/3EhKUm9

Polygenic risk scores for intraocular pressure and vertical cup-disc ratio demonstrated potential for improved early pre...
22/01/2025

Polygenic risk scores for intraocular pressure and vertical cup-disc ratio demonstrated potential for improved early prediction and risk stratification of glaucoma. https://ja.ma/4hj1wIK

Polygenic risk scores for primary open-angle glaucoma (POAG) show limited accuracy in individuals of African ancestry du...
21/01/2025

Polygenic risk scores for primary open-angle glaucoma (POAG) show limited accuracy in individuals of African ancestry due to a lack of genetic data from African populations. https://ja.ma/4gjmYwp

Most viewed in the last 7 days from JAMA Ophthalmology: No rebound effect on myopia progression was observed in particip...
20/01/2025

Most viewed in the last 7 days from JAMA Ophthalmology: No rebound effect on myopia progression was observed in participants switching from 0.01% atropine to placebo or tapering 0.01% atropine eye drops.

https://ja.ma/4h47uxu

Viewpoint: High rates of diagnostic errors in ophthalmology are often caused by cognitive biases, inadequate history tak...
20/01/2025

Viewpoint: High rates of diagnostic errors in ophthalmology are often caused by cognitive biases, inadequate history taking, and misinterpretation of physical examinations. https://ja.ma/4hhnawS

A 56-year-old woman presents with fever, headache, nausea, and vomiting. Computed tomography scan of the head shows mult...
19/01/2025

A 56-year-old woman presents with fever, headache, nausea, and vomiting. Computed tomography scan of the head shows multiple coarse, dystrophic calcifications, and she reports floaters with normal vision. What would you do next? https://ja.ma/4akqapS

In this quality improvement study, temperature excursions of anti-vascular endothelial growth factor agents above 8 °C f...
18/01/2025

In this quality improvement study, temperature excursions of anti-vascular endothelial growth factor agents above 8 °C for 48 hours or longer were reported for 28.9% of participants during home storage of the agents. https://ja.ma/4gXHlAg

Most viewed in the last 7 days from JAMA Ophthalmology: No rebound effect on myopia progression was observed in particip...
18/01/2025

Most viewed in the last 7 days from JAMA Ophthalmology: No rebound effect on myopia progression was observed in participants switching from 0.01% atropine to placebo or tapering 0.01% atropine eye drops.

https://ja.ma/4g4tyq8

Discontinuing multifocal contact lenses in older teenagers did not cause a rebound effect, with eye growth and myopia pr...
17/01/2025

Discontinuing multifocal contact lenses in older teenagers did not cause a rebound effect, with eye growth and myopia progression returning to normal rates. https://ja.ma/3WlFjS0

In this cross-sectional study, compared with graduating medical classes, female and Black students were underrepresented...
16/01/2025

In this cross-sectional study, compared with graduating medical classes, female and Black students were underrepresented among applicants and matriculants to ophthalmology residency. https://ja.ma/3DYTA0M

Most viewed in the last 7 days from JAMA Ophthalmology: A13-year-old male individual was referred to the ocular oncology...
15/01/2025

Most viewed in the last 7 days from JAMA Ophthalmology: A13-year-old male individual was referred to the ocular oncology service for evaluation of an optic nerve mass in the left eye.

https://ja.ma/4h9b6Oi

Case report discusses use of bedside manual repositioning of an anteriorly dislocated crystalline lens in a patient with...
14/01/2025

Case report discusses use of bedside manual repositioning of an anteriorly dislocated crystalline lens in a patient with Marfan syndrome. https://ja.ma/4095wWh

AI-based systems for detecting diabetic retinopathy have been FDA approved and show high sensitivity and specificity, bu...
13/01/2025

AI-based systems for detecting diabetic retinopathy have been FDA approved and show high sensitivity and specificity, but their adoption remains low compared to traditional imaging methods. https://ja.ma/3C3hKXn

Most viewed in the last 7 days from JAMA Ophthalmology: A13-year-old male individual was referred to the ocular oncology...
11/01/2025

Most viewed in the last 7 days from JAMA Ophthalmology: A13-year-old male individual was referred to the ocular oncology service for evaluation of an optic nerve mass in the left eye.

https://ja.ma/4j8AUvE

MOSAIC2 RCT: No rebound effect on myopia progression was observed in participants switching from 0.01% atropine to place...
10/01/2025

MOSAIC2 RCT: No rebound effect on myopia progression was observed in participants switching from 0.01% atropine to placebo or tapering 0.01% atropine eye drops. https://ja.ma/4afPZaD

Gene therapy for Bietti crystalline dystrophy (BCD) using adeno-associated virus encoding CYP4V2 showed some improvement...
09/01/2025

Gene therapy for Bietti crystalline dystrophy (BCD) using adeno-associated virus encoding CYP4V2 showed some improvement in vision over 12 months. https://ja.ma/3BPT9Fz

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