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JAMA Ophthalmology JAMA Ophthalmology is a member of the JAMA Network, a consortium of peer-reviewed publications.

A cross-sectional study of global retinopathy of prematurity (ROP) burden documented 8.79 million cases of ROP-related v...
26/12/2025

A cross-sectional study of global retinopathy of prematurity (ROP) burden documented 8.79 million cases of ROP-related visual loss from 1990 to 2021, with the majority occurring in countries with low and low-middle social demographic index (SDI). https://ja.ma/4b2J8nk

Structural alterations detected by HR-OCT enable in vivo identification of Bruch membrane calcification in pseudoxanthom...
26/12/2025

Structural alterations detected by HR-OCT enable in vivo identification of Bruch membrane calcification in pseudoxanthoma elasticum. This micron-level visualization distinguishes severity and supports HR-OCT as a valuable tool for diagnosis, monitoring, and trial design. https://ja.ma/48RVcGH

Case report: Oral tofacitinib achieved rapid and sustained remission in cases of refractory thyroid eye disease, targeti...
25/12/2025

Case report: Oral tofacitinib achieved rapid and sustained remission in cases of refractory thyroid eye disease, targeting proinflammatory cytokine pathways implicated in orbital fibroblast activation. https://ja.ma/44CFE7i

Multifocal geographic atrophy progresses faster and is linked to more rapid decline in visual acuity. Risk factors for n...
24/12/2025

Multifocal geographic atrophy progresses faster and is linked to more rapid decline in visual acuity. Risk factors for new lesion incidence include reticular pseudodrusen, noncentral GA, greater lesion proximity to the central macula, age, and dietary patterns such as lower fish and higher calorie intake. https://ja.ma/4axaF03

Rigid gas-permeable contact lenses led to greater visual acuity improvements compared with glasses in children after pri...
23/12/2025

Rigid gas-permeable contact lenses led to greater visual acuity improvements compared with glasses in children after primary congenital glaucoma surgery. Contrast sensitivity and near stereoacuity also improved, and no serious adverse events were reported. https://ja.ma/48RF9bZ

Advanced multimodal imaging indicates that vision loss in AZOOR initiates at the level of phototransduction within photo...
22/12/2025

Advanced multimodal imaging indicates that vision loss in AZOOR initiates at the level of phototransduction within photoreceptor outer segments. Optoretinography and adaptive optics microperimetry reveal abnormal cone elongation in areas of absolute scotoma. https://ja.ma/3ML2XFP

-1RA use was associated with reduced risk of developing nonexudative AMD but was not associated with progression to exu...
21/12/2025

-1RA use was associated with reduced risk of developing nonexudative AMD but was not associated with progression to exudative AMD among individuals with nonexudative AMD.

https://ja.ma/4pNGiY9

Among people with type 2 , risk of onset increased with higher HbA1C and frequent nonsevere hypoglycemia. https://ja....
20/12/2025

Among people with type 2 , risk of onset increased with higher HbA1C and frequent nonsevere hypoglycemia. https://ja.ma/4950fTa

This case report discusses a diagnosis of reticular epithelial corneal edema in a male patient aged 57 years who present...
19/12/2025

This case report discusses a diagnosis of reticular epithelial corneal edema in a male patient aged 57 years who presented with a sudden decrease in vision in his right eye, which was receiving treatment with netarsudil for neovascular . https://ja.ma/3YyPX8L

18/12/2025

Interview with Tien Y. Wong, MD, PhD, author of Aflibercept 8 mg in Polypoidal Choroidal Vasculopathy: Post Hoc Analysis of the PULSAR Randomized Clinical Trial. Hosted by Neil Bressler, MD. https://ja.ma/3Mxq6ve

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