Genes MDPI

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Genes MDPI

Genes (ISSN 2073-4425, IF 2.8) is an open access journal of genetics and genomics published monthly
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13/12/2024

📢 The Last session of Day 3 for the 2nd International Electronic Conference on Genes TODAY at 14:00pm CET on Zoom!
🎓 Session Chair Prof. Dr. Maria Luisa Chiusano of Session D is leading a captivating discussion on Technologies and Resources for Genetics Research. Don't miss this opportunity to gain valuable insights from the Keynote speaker Dr. Yuval Itan on the "Novel Machine Learning Approaches for Predicting Functional Consequences of Human Genetic Variants"

For a full program overview:
https://brnw.ch/21wPoFH

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13/12/2024

📢 Catch the Final Day of 2nd International Electronic Conference on Genes Day 3, wraps up its exciting journey TODAY at 09:00am CET on Zoom!
🎓 The Last day of the conference features Session Chair Prof. Dr. Dror Sharon of Session C. Human Genomics and Genetic Diseases, and Session Chair Prof. Dr. Maria Luisa Chiusano of Session D. Technologies and Resources for Genetics Research.
✅ Visit the full program overview:
https://brnw.ch/21wPoFz

12/12/2024

📢 The 2nd International Electronic Conference on Genes Day 2 continues its exciting journey TODAY at 09:00am CET on Zoom!
🧬The Second day of the conference features Session Chair Dr. Silvia Turroni of Session E. Microbial Genetics and Genomics, Keynote Speakers Dr. Federica D'Amico & Prof. Dr. Jianping Xu, and Invited Speaker Dr. Mariachiara Mengoli.
✅ Dive deeper into the full program of IECGE 2024 here: https://brnw.ch/21wPmSZ

11/12/2024

📢 Ready for more? We're back for the afternoon session of the 2nd International Electronic Conference on Genes at 14:00pm CET on Zoom!
Join us now as we delve deeper into the exciting world of Non-coding RNAs in Health and Diseases in Session B, Chaired by Prof. Dr. Laurent Metzinger.
🎓 Don't miss out on his insightful presentation on “Nobel price attributed to microRNAs timeline of the discovery and summarize the inaugural papers of Ambros and Ruvkun”
🎉 View the full program here:
https://brnw.ch/21wPmSO

11/12/2024

📢Don't miss the 2nd International Electronic Conference on Genes Day 1, starting TODAY at 09:00am CET on Zoom!

✅The conference, chaired by Prof. Dr. Selvarangan Ponnazhagan, included 3 invited speakers, 7 keynote speakers, and 17 selected speakers.

🎓The program boasts a variety of engaging sessions; featuring Session Chair Dr. Christos K. Kontos of Session B. Genetic Diagnosis and Targeted Therapy in Cancer, and Session Chair Prof. Dr. Laurent Metzinger of Session A. Non-coding RNAs in Health and Diseases.

🎉View the full program here:
https://brnw.ch/21wPmSK

28/11/2024

📣Registration for the 2nd International Electronic Conference on Genes closes in just 1 week!

👉This is your FREE opportunity to virtually explore cutting-edge advancements in Genes.
https://brnw.ch/21wP2Gt

🤝Join us for insightful presentations hosted by our renowned event chair, Prof. Dr. Selvarangan Ponnazhagan, along with 7 keynote speakers, 3 invited speakers, and 29 researchers!

📋Find the Program Overview here: https://brnw.ch/21wP2Gy

07/11/2024

We are at the American Society of Human Genetics Annual Meeting
If you’re attending as well, feel free to stop by our booth #1058 and meet our editors!

28/10/2024

📣FREE Registration for The 2nd International Electronic Conference on Genes held 11-13 December 2024 virtually!

Secure your spot before 6th December 2024 👉
https://bit.ly/4e3eyrC

🧬Showcase your inner Gene-ius and elevate your research to a global audience of esteemed colleagues, engage in stimulating discussions, and gain valuable insights from renowned geneticists and genomics experts!

Share your insights on these topics:
Non-coding RNAs in Health and Diseases
Genetic Diagnosis and Targeted Therapy in Cancer
Human Genomics and Genetic Diseases
Technologies and Resources for Genetics Research
Microbial Genetics and Genomics

28/06/2024

We will attend the ASHG Annual Meeting 2024 ( ), held in Denver, Colorado, USA, from 5 to 9 November 2024.

If you plan on attending this conference, stop by our booth #1058 and speak with our delegates!
https://www.mdpi.com/journal/genes/announcements/8743

05/01/2024

We are excited to announce the 2nd International Electronic Conference on Genes (IECGE2024). It will be chaired by Dr. Selvarangan Ponnazhagan on 11–13 Dec 2024.
Choose one session to prepare and submit your abstract by 8th September 2024 at https://bit.ly/48pfjsK
Our session topics are:
A. Non-coding RNAs in Health and Diseases
B. Single-cell RNA Sequencing
C. Genetics and Genomics of Neurodegenerative Diseases
D. Genetic Diagnosis and Targeted Therapy in Cancer
E. Human Genomics and Genetic Diseases
F. Technologies and Resources for Genetics Research
G. Microbial Genetics and Genomics

20/12/2023

syndrome (KS) is a developmental disorder principally comprised of developmental delay, hypotonia and a clearly defined dysmorphism: elongation of the structures surrounding the eyes, a shortened and depressed nose, thinning of the upper lip and thickening of the lower lip, large and prominent ears, hypertrichosis and scoliosis. Other characteristics include poor physical growth, cardiac, gastrointestinal and renal anomalies as well as variable behavioral issues, including autistic features. This paper reviews the current clinical knowledge, provides molecular and scientific links and sheds light on the treatment of Kabuki syndrome individuals.

Please read more details by clicking the link:
bit.ly/4aw3lza

20/12/2023

(GBM) is the most common primary malignant brain tumour in adults. Though literature data suggest that distinct GBM’s subtypes harbour differences in their , its role in treatment response remains obscure. However, an in-depth investigation of GBM’s microenvironment may lead to novel therapeutic opportunities to improve patients’ outcomes. This review will elucidate the GBM’s microenvironment composition, highlighting the current state of the art in approaches. Authors will focus on novel strategies of active and passive immunotherapies, including vaccination, gene therapy, checkpoint blockade, and adoptive T-cell therapies.

Please read more details by clicking the link:
bit.ly/4asiwtc

19/12/2023

currently included in leguminosarum are too diverse to be considered a single species, so they could be referred to this as a species complex ( Rlc). Authors have found 429 publicly available genome sequences that fall within the Rlc and these show that the Rlc is a distinct entity, well separated from other species in the genus. Its sister taxon is R. anhuiense. Authors constructed a phylogeny based on concatenated sequences of 120 universal (core) genes, and calculated pairwise average nucleotide identity (ANI) between all genomes. These analyses show the Rlc includes 18 distinct genospecies, plus 7 unique strains that are not placed in these genospecies.

Please read more details by clicking the link:
bit.ly/3GQpSJs

19/12/2023

is generally expected to have a stronger unfavorable effect on fitness traits than on other traits. Traditionally, the degree of inbreeding depression in has been estimated as the slope of the linear regression of phenotypic values on pedigree-based inbreeding coefficients. Authors performed a meta-analysis of 154 studies, published from 1990 to 2020 on seven livestock species, and compared the degree of inbreeding depression (1) across different trait groups, and (2) across different pedigree-based and SNP-based measures of inbreeding.

Please read more details by clicking the link:
bit.ly/3tydAlU

18/12/2023

The inosine plays an important role in purine biosynthesis, gene translation,and modulation of the fate of RNAs. The editing of adenosine to inosine is a widespread posttranscriptional modification in transfer RNAs ( ) and messenger RNAs ( ). At the wobble position of tRNA anticodons, inosine profoundly modifies codon recognition, while in mRNA, inosines can modify the sequence of the translated polypeptide or modulate the stability, localization, and splicing of transcripts. Inosine is also found in non-coding and exogenous RNAs, where it plays key structural and functional roles. In addition, molecular inosine is an important metabolite in purine metabolism that also acts as a molecular messenger in cell signaling pathways. Authors review the functional roles of in biology and their connections to human health.

Please read more details by clicking the link:
bit.ly/3GNAfxN

18/12/2023

Since phenomena are interdependent, treatment modalities include co-administration of two different epigenetic . In order to sensitize cells to chemotherapy, epigenetic drugs are administered prior to chemotherapy, or both epigenetic drug and chemotherapy are used together to achieve synergistic effects and maximize efficacy. The combinations of epigenetic drug with are being tested, because they have proved to enhance antitumor immune responses. The next approach involves targeting the metabolic causes of epigenetic changes, i.e., enzymes which, when mutated, produce oncometabolites. Finally, editing makes it possible to modify individual chromatin marks at a defined region with unprecedented specificity and efficiency. This review summarizes the above attempts in fulfilling the promise of epigenetic drugs in the effective cancer treatment.

Please read more details by clicking the link:
bit.ly/47YmWXh

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