Microbiology learning media - MLM

31/01/2022

https://youtu.be/M79ti8h_mqA

How interesting is the viruses!!!They sn**ch the cap from the host mRNA to complete their transcription....Isn't it INTERESTING!!Cap sn**ching mechanism is w...

30/01/2022

It's world neglected tropical disease day!!! Post from

29/01/2022

https://youtu.be/fr0rAJZJ9z0
Please check this out!!

07/07/2021

05/07/2021

https://www.tocris.com/resources/molarity-calculator

Use the Molarity Calculator to calculate the mass, volume or concentration required to prepare a solution of compound of known molecular weight.

05/07/2021

https://www.tocris.com/resources/dilution-calculator

The leading supplier of novel and exclusive research tools including GPCR ligands, neurotransmitters, ion channel modulators and signaling inhibitors.

01/07/2021

https://youtu.be/sT5JpQU73dk

20/06/2021

https://www.frontiersin.org/articles/10.3389/fphar.2020.588561/full #:~:text=10.3389%2Ffphar.2020.588561-,Potential%20Application%20of%20Drosophila%20melanogaster%20as%20a,in%20COVID%2D19%2DRelated%20Research&text=Since%20December%202019%2C%20the%20severe,2019%20(COVID%2D19).

In the presence of ethical constraints to perform explorative research on humans, the use of proper model organisms to address the above unrequited yet essential aspects of COVID-19 are urgently required. With the aid of suitable animal models, the pharmacodynamics and pharmacokinetic profiles as we...

08/06/2021

The term acute encephalitis syndrome (AES) was coined by the WHO in 2008.

The symptoms of AES include an acute onset of fever and associated clinical neurological manifestations such as mental confusion, disorientation, delirium, convulsions, or coma.

Early symptoms include headaches and vomiting, along with sudden hypoglycemia (drops in blood sugar levels), but may lead to coma, brain dysfunctions, and inflammation of the heart and lungs. The severe hypoglycemia can cause death. The syndrome is locally known as Chamki Bukhar in Bihar.

Cause s

The cause of the outbreak is unclear.

AES can be caused by different microorganisms including virus, bacteria, fungi, parasites and spirochetes, as well as chemicals and toxins. AES mostly affects children below 15. In India, AES was chiefly associated with Japanese encephalitis virus (JEV) before 1975. The JEV cases and outbreaks became more frequent and endemic regions developed between 1975 and 1999. After 1999, non-JEV cases and outbreaks of AES were increasingly reported caused by other viruses including Chandipura virus (CHPV), Nipah virus (NiV), and enteroviruses. After 2012, it is observed that the cause shifting to JEV.

High temperature
humidity
malnutrition
poor hygiene
and lack of awareness are known aggravating factors of AES

Cases of AES tend to occur during the country's monsoon season. In June 2019, the temperature in Muzaffarpur had remained above 40 °C (104 °F) and the rains were delayed which might have aggravated the situation. Poverty and malnutrition is widespread among children in the region. Malnourished children lack a buffer stock of sugar as glycogen in the liver which puts them at higher risk of hypoglycemia.

Lychee fruits, which naturally include toxins related to encephalitis, are suspected to have been a contributing factor in the outbreak.
The region is the largest producer of lychee fruits in India. A 2014 study published in Lancet found that the methylene cyclopropyl acetic acid and hypoglycin A found in unripe lychee (Litchi chinensis) fruit can cause hypoglycemia and cited them as plausible cause of AES outbreaks. A diet heavy on unripe lychee fruits without having an otherwise full meal later in the day may put malnourished children at risk of hypoglycemia.

08/06/2021

Oncogenic viruses

07/06/2021

💥Eastern blot is a molecular biology technique that is used to detect post-translational modifications in proteins and the presence of components like lipids and carbohydrates.
💥Eastern blot was discovered as an extension of the more popular western blotting technique.
💥Eastern blot is primarily performed to detect the presence of biomolecules in different proteins, which can be used to study the differences in the post-translational modifications in different species.
💥The principle and procedure of the method are similar in all blotting techniques; however, the molecule or particle to be detected might differ.
💥Eastern blot has been slightly modified to form a new form of blotting technique called far-western blotting, which is used to study lipids that are separated by chromatography.

02/06/2021

Power of books and science!
Black fungus

22/05/2021

https://youtu.be/6n2vGHXex0g