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Renal & Urology News Clinical news for nephrologists and urologists.
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Extending wait time from 1 to 3 hours after withdrawal of life support for donation after circulatory death does not c...
23/11/2024

Extending wait time from 1 to 3 hours after withdrawal of life support for donation after circulatory death does not compromise outcomes -- and it may help ease the organ shortage.

Investigators conducted the largest study to date on donation after circulatory death criteria.

Significant bidirectional associations seen for obstructive sleep apnea, restless leg syndrome, insomnia with CKD.
23/11/2024

Significant bidirectional associations seen for obstructive sleep apnea, restless leg syndrome, insomnia with CKD.

Significant bidirectional associations seen for obstructive sleep apnea, restless leg syndrome, insomnia with CKD

Glucagon-like peptide-1 receptor agonist (GLP-1 RA) use may reduce alcohol consumption and improve outcomes in some indi...
23/11/2024

Glucagon-like peptide-1 receptor agonist (GLP-1 RA) use may reduce alcohol consumption and improve outcomes in some individuals.

However, authors caution there is little high-quality evidence

Tubulointerstitial inflammation in patients with lupus nephritis is a marker of heightened risk for progression to chron...
22/11/2024

Tubulointerstitial inflammation in patients with lupus nephritis is a marker of heightened risk for progression to chronic disease (CKD) and end-stage kidney disease (ESKD).

Studies investigating what is damaging the kidney in lupus nephritis point to tubulointerstitial inflammation.

TryvioTM (aprocitentan) is now available for the treatment of hypertension in combination with other antihypertensive dr...
22/11/2024

TryvioTM (aprocitentan) is now available for the treatment of hypertension in combination with other antihypertensive drugs, to lower blood pressure (BP) in adult patients who are not adequately controlled on other drugs.

Tryvio (aprocitentan) is now available for difficult-to-control hypertension in combination with other antihypertensive drugs.

As many as 40% of cancer patients receiving immune checkpoint inhibitors (ICIs) experience immune-related adverse events...
22/11/2024

As many as 40% of cancer patients receiving immune checkpoint inhibitors (ICIs) experience immune-related adverse events.

As many as 40% of cancer patients receiving immune checkpoint inhibitors (ICIs) experience immune-related adverse events (AEs).

For patients with type 2 diabetes and elevated systolic blood pressure, an intensive-treatment strategy is better than a...
22/11/2024

For patients with type 2 diabetes and elevated systolic blood pressure, an intensive-treatment strategy is better than a standard-treatment strategy for incidence of major cardiovascular disease events.

Significantly lower incidence of major cardiovascular events seen with intensive- versus standard-treatment strategy

For patients with type 2 diabetes mellitus (T2DM), glucagon-like peptide 1 receptor agonist (GLP-1 RA) use is associated...
21/11/2024

For patients with type 2 diabetes mellitus (T2DM), glucagon-like peptide 1 receptor agonist (GLP-1 RA) use is associated with a lower risk for venous thromboembolism (VTE).

Significant reduction seen in VTE rates, with similar reductions for patients with and without obesity

Public health measures that curtail individual freedoms must be necessary, effective, proportional to the health threat,...
21/11/2024

Public health measures that curtail individual freedoms must be necessary, effective, proportional to the health threat, and the least restrictive interventions available.

Government efforts to protect public health have to balance the potential benefits of interventions against impact on individual freedoms.

There is a dose-response relationship between rising outdoor temperatures and increased atrial fibrillation events.
21/11/2024

There is a dose-response relationship between rising outdoor temperatures and increased atrial fibrillation events.

Doubling to tripling of odds seen when temperatures reach extreme heat levels

New survey results suggest that, although cancer patients and their loved ones value faster access to new cancer drugs, ...
21/11/2024

New survey results suggest that, although cancer patients and their loved ones value faster access to new cancer drugs, they are often willing to wait for the approval of drugs that are more likely to provide a survival benefit.

Survey results suggest that cancer patients are willing to wait for the approval of drugs that are more likely to provide a survival benefit.

More than 2-fold increased bleeding rate seen with NSAID use for patients treated with oral anticoagulants for VTE.
20/11/2024

More than 2-fold increased bleeding rate seen with NSAID use for patients treated with oral anticoagulants for VTE.

More than 2-fold increased bleeding rate seen with NSAID use for patients treated with oral anticoagulants for VTE

In a real-world study, only 35% of patients completed the full guideline-recommended 4-6 cycles of chemotherapy as first...
20/11/2024

In a real-world study, only 35% of patients completed the full guideline-recommended 4-6 cycles of chemotherapy as first-line treatment for metastatic bladder cancer.

More than one third of patients receiving first-line chemotherapy for metastatic bladder cancer did not have guideline-recommended treatment adherence.

Su***de rates have increased for cancer patients of all ages, but the highest su***de death rate was observed in adolesc...
20/11/2024

Su***de rates have increased for cancer patients of all ages, but the highest su***de death rate was observed in adolescent and young adult (AYA) males.

Rates of su***de have increased for cancer patients of all ages, but the highest su***de death rate was observed in male adolescents and young adults.

Investigators predict that patients with chronic kidney disease (CKD), type 2 diabetes, or both have elevated cardiovasc...
20/11/2024

Investigators predict that patients with chronic kidney disease (CKD), type 2 diabetes, or both have elevated cardiovascular disease (CVD) risk from 8 to 28 years sooner than adults without those conditions.

Adults with chronic kidney disease (CKD) or type 2 diabetes develop cardiovascular diseases (CVD) at younger ages.

Many young patients with early-onset cancer report having a fertility preservation (FP) discussion with their health car...
20/11/2024

Many young patients with early-onset cancer report having a fertility preservation (FP) discussion with their health care professional prior to treatment.

Prevalence lowest for those with thyroid, lung or bronchus, ovarian, and colorectal cancers

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