STM Publishing Group Pty Ltd

13/12/2025

Mitochondrial protection role of oxidoreductase-like domain containing 1 in myocardial cells under hypoxia.
Researchers at Chinese PLA General Hospital and Capital Medical University show that the protein protects cardiomyocytes under by enhancing mitochondrial function through and , reducing and boosting production.
in : https://doi.org/10.4103/mgr.MEDGASRES-D-24-00117

12/12/2025

Dark white matter is a subcortical MRI marker in seizures and systemic disorders: A narrative review
Researchers at "Giovanni Paolo II" Hospital in Italy show that "Dark White Matter" (DWM)—a subcortical T2/FLAIR hypointensity on MRI—is a reproducible and underrecognized biomarker of recent seizure activity and transient subcortical dysfunction, frequently linked to conditions like non-ketotic hyperglycemia and autoimmune encephalitis (especially MOGAD).
in : https://doi.org/10.1016/j.neumar.2025.100126

11/12/2025

Harnessing the immune system and developing targeted vaccines: overall strategies of leveraging the body’s natural defense mechanisms to enhance cancer treatment
Researchers at Auburn University and Islamia College of Science and Commerce show that harnessing the immune system through targeted vaccines—including next-generation, multi-antigen, and personalized strategies—can overcome tumor immune evasion and enhance cancer treatment efficacy.
in : https://doi.org/10.4103/REGENMED.REGENMED-D-25-00011

09/12/2025

Advances in myoelectric neuroprosthetics: A narrative review of current trends, challenges, and future directions
Researchers at Nanyang Technological University and Singapore General Hospital show that are transforming rehabilitation and assistive devices by decoding muscle signals for intuitive bionic limb and exoskeleton control, leveraging advances in machine learning, surgical interfaces, and shared autonomy.
in : https://journals.lww.com/atn/fulltext/2025/12000/advances_in_myoelectric_neuroprosthetics__a.6.aspx

05/12/2025

Biases and consistency of different assay methods for neurological biomarkers using Quanterix single-molecule-array technology: A comparative study of the secondary analysis method
Researchers at University of British Columbia show that different Quanterix Simoa assay formulations for measuring neurological biomarkers Neurofilament Light Chain (NfL) and Glial Fibrillary Acidic Protein (GFAP) can exhibit significant biases, highlighting the need for data harmonization to ensure comparability across studies and support clinical translation.
in : https://doi.org/10.1016/j.neumar.2025.100147

04/12/2025

Inflammation-linked apolipoprotein-L activities: immunity control, mitochondrial repair, pathogen resistance, and disease induction
Researchers at Université Libre de Bruxelles show that apolipoprotein-L (APOL) proteins—APOL1, APOL2, and APOL3—play crucial roles in -linked processes, including , , , and disease mechanisms such as and .
in : https://doi.org/10.4103/REGENMED.REGENMED-D-25-00027

03/12/2025

Multifaceted role of nitric oxide in vascular dementia
Researchers at Yangzhou University and the University of Pittsburgh School of Medicine show that plays a multifaceted role in —regulating synaptic plasticity, modulating neuroinflammation, and protecting blood-brain barrier integrity—highlighting the NO-sGC-cGMP pathway as a promising therapeutic target.
in : https://doi.org/10.4103/mgr.MEDGASRES-D-24-00158

02/12/2025

Association between age-related cardiovascular disease and systemic lupus erythematosus: a Mendelian randomization analysis
Researchers at Anhui University of Science & Technology and Shenzhen Traditional Chinese Medicine Hospital show that certain age-related heart diseases—including valvular heart disease, hypertensive heart disease, and endocarditis—are genetically linked to an increased risk of developing systemic lupus erythematosus (SLE). Using Mendelian randomization, the study identifies shared genetic variants and suggests that patients with these cardiac conditions should be monitored for SLE.
in : https://doi.org/10.4103/AGINGADV.AGINGADV-D-25-00029

01/12/2025

Current frontier technologies in spinal cord injury research: A narrative review
Researchers at Tianjin Medical University General Hospital show that spinal cord injury treatment is shifting from single-method approaches to integrated multimodal strategies—combining , , , , and to advance functional recovery and neural repair.
in : https://journals.lww.com/atn/fulltext/2025/12000/current_frontier_technologies_in_spinal_cord.4.aspx

29/11/2025

Dark white matter is a subcortical MRI marker in seizures and systemic disorders: A narrative review
Researchers at the Italy "Giovanni Paolo II" Hospital show that Dark White Matter (DWM)—a reversible T2/FLAIR hypointensity in subcortical white matter—is a novel MRI biomarker for recent seizure activity, especially in and like .
in : https://doi.org/10.1016/j.neumar.2025.100126

28/11/2025

The epidemiology and burden of global osteoarthritis: a systematic analysis based on the Global Burden of Disease database
Researchers at the Tianjin Sports Institute and Tianjin Hospital show that the global burden of osteoarthritis is rising, driven significantly by an aging population, high body mass index, and metabolic risks. Their analysis of the Global Burden of Disease database projects that by 2035, the global prevalence may exceed 12,000 cases per 100,000 people. This study highlights the critical need for targeted public health strategies to address this growing challenge.
in : https://doi.org/10.4103/AGINGADV.AGINGADV-D-25-00003

27/11/2025

Application of machine learning technology and miRNA biomarkers: A novel approach for epilepsy diagnosis
Researchers at UC San Diego show that combining with can accurately diagnose using nucleotide sequences and target gene patterns—offering a novel, non-invasive, and accessible diagnostic tool.
in : https://doi.org/10.4103/ATN.ATN-D-25-00017

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