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Exclusive news, features, and analysis on the research, tools, regulations, and applications driving the future of precision medicine with the ultimate goal of transforming patient care and outcomes. Driven by a rapid and exponentially growing market – one that is expected to be valued at more than $126 billion by 2025 – and our commitment to covering the full breadth of the revolutionary field of

precision medicine, Clinical OMICs is now Inside Precision Medicine! Inside Precision Medicine is the only global media brand covering the full spectrum of precision medicine, taking a wide lens approach while bringing into sharp focus the many complex and interconnected issues that constitute the field. From our core areas of Translational Research, Molecular Diagnostics, Informatics, and Patient Care, to our expanded coverage of Disease Indications and Payer/Regulatory issues, our best-in-class content informs, educates, and enlightens our diverse audience of leading decision-makers.

14/01/2025

Stroke Prediction Boosted By Retinal Imaging

Retinal imaging of the back of the eye can help predict stroke in a non-invasive manner by measuring 29 different vascular features, shows new research led by The Hong Kong Polytechnic University - PolyU and The University of Melbourne.

Retinal imaging of the back of the eye can help predict stroke in a non-invasive manner by measuring 29 different vascular features.

14/01/2025

New AI-Based Tool Better Matches Patients to Cancer Trials

A new study showed that a first-of-its-kind, AI-based platform could help clinicians and patients assess whether and how much an individual may benefit from a particular therapy in a clinical trial. The study was led by Ravi B. Parikh, MD, at Winship Cancer Institute of Emory University and co-led by Qi Long, PhD, at the University of Pennsylvania.

A new study showed that a first-of-its-kind, AI-based platform could help clinicians and patients assess whether and how much an individual may benefit from a particular therapy in a clinical trial.

14/01/2025

Researchers Discover Unique Skeletal Tissue with Potential for Regenerative Medicine

An international team of researchers, led by investigators at UC Irvine uncovered the skeletal tissue known as "lipocartilage." The tissue is found in mammals' ears, noses, and throats, and has properties that make it resilient and flexible.

Known as "lipocartilage," the tissue is found in mammals' ears, noses, and throats, and has properties that make it resilient and flexible.

14/01/2025

New AI-Based Tool Predicts Patient’s ICI Response Without Genomics

The The Mount Sinai Hospital researchers SCORPIO model was validated using data from 9,745 patients across 21 cancer types treated with ICIs.

The first machine learning-based tool that can predict immune checkpoint inhibitor (ICI) response using routine clinical data has been developed.

14/01/2025

Timberlyne Therapeutics Launched Last Week with a $180 Million Series A Financing

The financing will advance CM313, an IgG1 monoclonal antibody with enhanced complement-dependent cytotoxicity that targets CD38.

Timberlyne Therapeutics launched last week with a $180 million Series A financing to advance CM313.

13/01/2025

New Insights into T-Cell Role in Viral Defense Could Transform Vaccine Strategies

The research findings, from Duke-NUS Medical School and the Singapore General Hospital, challenge the long-standing assumption that antibodies are the primary defense against acute viral diseases.

The findings suggest that vaccine strategies should also take into account T-cell response in addition to antibody response.

13/01/2025

Sensitive Tumor DNA Test Effective at Predicting Lung Cancer Progression

A test developed by U.S.-biotech Personalis, Inc. can pick up small amounts of lung cancer tumor DNA in the blood and predict patient outcomes.

Francis Crick Institute (UK Centre for Medical Research and Innovation),

A test developed by U.S.-biotech Personalis can pick up small amounts of lung cancer tumor DNA in the blood and predict patient outcomes.

13/01/2025

FDA Clears Solid Biosciences Neurodegeneration Gene Therapy IND

The AAV-based candidate will deliver full-length frataxin (FXN) to treat both brain and heart manifestations of Friedreich’s ataxia, an industry first.

U.S. Food and Drug Administration

The AAV-based candidate will deliver full-length frataxin (FXN) to treat both brain and heart manifestations of Friedreich’s ataxia, an industry first.

13/01/2025

JPM 2025: NVIDIA, Mayo Clinic Partner on AI-Powered Digital Pathology

The initiative will build and power the infrastructure required to digitize and deliver impactful AI-driven pathology solutions to patients and caregivers. Read more of Jonathan D. Grinstein, PhD's coverage of the J.P. Morgan annual healthcare conference.

The initiative will build and power the infrastructure required to digitize and deliver impactful AI-driven pathology solutions to patients and caregivers.

13/01/2025

Structural Divergence in PD-1 Across Species May Explain Functional Differences and the Need for New Preclinical Models

The UC San Diego study refutes Previously unknown structural differences in the PD-1 immunotherapy target refute assumptions that it functions similarly in rodents and humans.

Previously unknown structural differences in the PD-1 immunotherapy target refute assumptions that it functions similarly in rodents and humans.

10/01/2025

Tongue Cancer Organoids Reveal Key Pathways for Overcoming Drug Resistance

A research team at the Institute of Science Tokyo has developed a novel library of patient-derived tongue cancer organoids. The organoids could suggest new drugs targeting autophagy and cholesterol synthesis pathways to treat the most common oral cancer, and one that often carries a poor prognosis.

The organoids could suggest new drugs targeting autophagy and cholesterol synthesis pathways to treat the most common oral cancer.

10/01/2025

Groundbreaking Human Protein Study Launches

The UK Biobank has launched the largest and most comprehensive study into blood proteins to date, with the hope that it will transform research into new tests, biomarkers, and treatments for disease. The Human Proteome Study will allow researchers to better understand how genetic makeup, lifestyle, and environment influences disease through changes in circulating protein levels.

The UK Biobank has launched the world’s most comprehensive study of circulating proteins, which is set to transform the study of diseases and their treatments.

10/01/2025

Aspect Biosystems Raises $115M for Bioprinted Tissue Therapeutics

The round was led by Dimension, a multistage investment firm “dedicated to the interface of technology and the life sciences,” with participation from Novo Nordisk, Radical Ventures, an undisclosed leading global investment firm, InBC, Pallasite Ventures, Pangaea Ventures, Rhino Ventures, and T1D Fund: A Breakthrough T1D Venture.

Regenerative medicine company, Aspect Biosystems has closed a US$115M Series B financing round.

09/01/2025

New Test Predicts Survival in Early-Stage Lung Cancer Better than Current Methods

The findings could allow doctors to identify which patients with stage I lung cancer would benefit from chemotherapy and surgery—information that current clinical standard testing is not able to provide.

The findings could allow doctors to identify which patients with stage I lung cancer would benefit from chemotherapy and surgery.

09/01/2025

Massive Mouse Study Shows Not All Brain Cells Age the Same

A researcher team, from the Allen Institute for Brain Research, investigated how different cell types in the mouse brain change at the genetic level with age. By analyzing single-cell transcriptomes from young and old mice, the researchers identified key gene expression shifts linked to aging.

By analyzing over 1.2 million single-cell transcriptomes from young and old mice, key gene expression shifts linked to aging were identified.

09/01/2025

Questions Raised over Opioid Use Disorder Algorithm

Researchers have cast doubt over the accuracy of an algorithm that has recently received pre-marketing approval by U.S. regulators to predict the risk of opioid use disorder.

Researchers have cast doubt over the accuracy of an algorithm that has recently received pre-marketing approval by U.S. regulators to predict the risk of opioid use disorder.

09/01/2025

Two Blood Biomarkers Linked to Early Alzheimer’s Disease

The findings could lead to a blood test identifying those who have Alzheimer’s disease, and potentially those who are at greater risk of developing early dementia. They could also shed light on why Alzheimer’s affects more women than men. The research was led by NYU Grossman School of Medicine and the Institute of Medical Biochemistry Leopoldo de Meis in Brazil.

Two carnitine biomarkers are strongly predictive of cognitive decline and could form the basis of a future blood test for Alzheimer's disease.

08/01/2025

🎧 Treating the Not-So-Rare “Rare Disease” Patients at Major Care Centers

With pharmacogenetic testing and 5-base sequencing, Tomi Pastinen, MD, PhD, is bringing precision medicine to all kids at Children's Mercy Kansas City (CMKC). Jonathan D. Grinstein, PhD, and Dr. Pastinen, the director of the Center for Pediatric Genomic Medicine at CMKC, discuss some challenges that arise when going from a genetically characterized diagnosis to actual treatment as well as the world beyond well-defined inherited diseases to more complex disorders, including autism.

Don't miss the latest issue of Behind the Breakthroughs!

With pharmacogenetic testing and 5-base sequencing, Tomi Pastinen, MD, PhD, is bringing precision medicine to all kids at Children’s Mercy Kansas City.

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Be sure to tune in for the 2024 State of Biotech virtual summit on September 11th, 2024. This completely free event is hosted by GEN editors and brings together industry leading experts across the field of biotech. Register now and join us at 11am EST. h

Be sure to tune in for the 2024 State of Biotech virtual summit on September 11th, 2024. This completely free event is hosted by GEN editors and brings together industry leading experts across the field of biotech. Register now and join us at 11am EST. https://hubs.li/Q02Pr5Vd0

We recently hosted a staff celebration that perfectly embodied the spirit of teamwork and innovation. Despite the weather, our Amalfi Coast-themed indoor picnic brought colleagues together for a fun-filled evening of games, Karaoke, and creative activiti

We recently hosted a staff celebration that perfectly embodied the spirit of teamwork and innovation. Despite the weather, our Amalfi Coast-themed indoor picnic brought colleagues together for a fun-filled evening of games, Karaoke, and creative activities. This event wasn’t just a break from work; it was a chance to celebrate the successes we’ve achieved so far this year and to strengthen the bonds that drive our continued growth. A big thank you to everyone who helped make this gathering such a success. Here’s to the exciting journey ahead! 🎉 #staffparty #teamwork #funatwork #teambonding #workhardplayhard #colleagues

📣 Announcing RFS Awardees in Biomedical Research! We are thrilled to recognize the exceptional contributions of women and underrepresented minorities in STEM. The Rosalind Franklin Society, in partnership with our p

📣 Announcing RFS Awardees in Biomedical Research! We are thrilled to recognize the exceptional contributions of women and underrepresented minorities in STEM. The Rosalind Franklin Society, in partnership with our publisher Mary Ann Liebert, Inc., publishers, has awarded $100,000 to researchers making significant strides in biomedical research. 🌟 Explore the groundbreaking research of these trailblazing scientists and celebrate their achievements with us. 🧬🔬 Acknowledging the support from the Rita Allen Foundation, Lyda Hill Philanthropies and the Warren Alpert Foundation. 🔗 https://hubs.li/Q02KBjY10 #WomenInSTEM #MinoritiesInSTEM #ScientificExcellence #BiomedicalResearch University Health Network Linköping University Novaflux University of California San Francisco Fondazione IRCCS Istituto Nazionale dei Tumori Wayne State University School of Medicine University of Toronto North Carolina State University Universität Zürich Máxima MC National Institutes of Health (NIH) Carleton University University of Manitoba University of Oxford University of Nevada, Las Vegas University of Nottingham Istituto Superiore Di Sanità National Hellenic Research Foundation University of Santo Tomas UNAM Universidad Nacional Autónoma de México

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About the Publication

Clinical OMICs is the leading source of practical insights for pathologists, clinicians, researchers, and scientists working to translate important findings across the broad range of “omics” technologies to deliver on the promise of molecular and precision medicine for patients.

Through a combination of industry news, features, and thoughtful analyses, Clinical OMICs emphasizes the practical—relevant knowledge and available tools—and empowers healthcare professionals to harness the application of molecular-based technologies and transform patient care. From sequencers and biomarkers to software and clinical decision support and everything in between, Clinical OMICs helps its readers stay current on the most critical research, tools, regulations, and applications affecting the practice of molecular pathology, the development of omics technologies and diagnostics, and the delivery of precision medicine.

Clinical OMICs provides readers with up-to-date content through its bimonthly Magazine, eNewsletters, and daily articles available on ClinicalOMICs.com.

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Be sure to tune in for the 2024 State of Biotech virtual summit on September 11th, 2024. This completely free event is hosted by GEN editors and brings together industry leading experts across the field of biotech. Register now and join us at 11am EST. h

We recently hosted a staff celebration that perfectly embodied the spirit of teamwork and innovation. Despite the weather, our Amalfi Coast-themed indoor picnic brought colleagues together for a fun-filled evening of games, Karaoke, and creative activiti

📣 Announcing RFS Awardees in Biomedical Research! We are thrilled to recognize the exceptional contributions of women and underrepresented minorities in STEM. The Rosalind Franklin Society, in partnership with our p

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