Retina

TIME-COURSE RETINAL CIRCULATION CHANGES IN EYES WITH CENTRAL RETINAL ARTERY OCCLUSION USING LASER SPECKLE FLOWGRAPHY Tanaka, Shin MD, PhD; Soga, Naoki MD; Hirono, Kazushi MD; Okawa, Kazuyoshi MD; Chin, Jacob Y. H. MD; Kitahata, Shohei MD, PhD; Inoue, Tatsuya MD, PhD; Maruyama-Inoue, Maiko MD, PhD; Kadonosono, Kazuaki MD, PhD Retina 45(1):p 133-140, January 2025 Laser speckle flowgraphy showed that the retinal circulation improved significantly within 1 month and younger patients had better improvement in the retinal circulation in eyes with central retinal artery occlusion. The baseline best-corrected visual acuity and retinal circulation within 1 month were correlated with the final best-corrected visual acuity. https://journals.lww.com/retinajournal/abstract/2025/01000/time_course_retinal_circulation_changes_in_eyes.17.aspx #retina #CRAO #LSFG #Retina #Retinal circulation

FACTORS DEFINING DENSITY OF RETINAL MACROPHAGE-LIKE CELLS DISPLAYED WITH OPTICAL COHERENCE TOMOGRAPHY Maltsev, Dmitrii S. MD, DSc; Kulikov, Alexei N. MD, DCs; Gorlova, Arina S. MD; Vasiliev, Alexander S. MD Retina 45(1):p 117-127, January 2025 Retinal macrophage-like cell density correlates with axial length, refractive error, choroidal thickness, age, and status of the vitreoretinal interface. The latter directly defines macrophage-like cell density, although axial length may play a basic role. https://journals.lww.com/retinajournal/abstract/2025/01000/factors_defining_density_of_retinal.15.aspx #retina @maltsev_md #retinalimaging #retinaldisease

A NOVEL FOUR-POINT SCLERAL FIXATION TECHNIQUE WITH A HYDROPHOBIC INTRAOCULAR LENS The Loop to Optic and Trailing end to Outside Technique Ghazi, Nicola G. MD; Goldsmith, Jason MD; Weston, James PhD; Sabah, Shafiya MS; Teo, Jeremy C.M. PhD, MEng Retina 45(1):p 107-116, January 2025 The authors describe a novel four-point intraocular lens scleral fixation technique that offers several advantages over previously reported techniques, including using a readily available hydrophobic intraocular lens and avoiding conjunctival and scleral manipulation (flaps/pockets). https://journals.lww.com/retinajournal/abstract/2025/01000/a_novel_four_point_scleral_fixation_technique_with.14.aspx #retina

NONPHARMACOLOGICAL ASPECTS OF INTRAVITREAL DEXAMETHASONE IMPLANT INJECTIONS A Retrospective Study of 3,430 Injections and Complications Kiristioglu, Mehmet Omer MD; Ucan Gunduz, Gamze MD; Abdullayeva, Nigar MD; Doganay, Selim MD; Yalcinbayir, Ozgur MD Retina 45(1):p 95-106, January 2025 In this 10-year real-world study, nonpharmacological complications after intravitreal dexamethasone implantation at a single center are presented alongside the characteristics of the cases. Risk factors for these nonpharmacological complications have been identified. https://journals.lww.com/retinajournal/abstract/2025/01000/nonpharmacological_aspects_of_intravitreal.13.aspx #retina @uludagkurumsal

ANTERIOR SUBTENON TRIAMCINOLONE INJECTION FOR REFRACTORY MACULAR EDEMA A Retrospective Case Series Felfeli, Tina MD, PhD; Park, Megan BSc; Gorfinkel, Nathan S. BSc; Shwarzman, Robert; Papanikolaou, John; Shah, Paresh; Kiss, Alex PhD; Mandelcorn, Efrem D. MD, FRCSC Retina 45(1):p 88-94, January 2025 This retrospective study evaluates the effectiveness of anterior subtenon triamcinolone injection in the management of refractory macular edema. Anterior subtenon triamcinolone is an effective treatment for refractory macular edema, notably improving anatomic and functional outcomes. https://journals.lww.com/retinajournal/abstract/2025/01000/anterior_subtenon_triamcinolone_injection_for.12.aspx #retina @TinaFelfeli

VASCULAR CHANGES AND IRREVERSIBLE COMPLICATIONS IN 120° FUNDUS USING WIDEFIELD SWEPT-SOURCE OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY IN VOGT–KOYANAGI–HARADA DISEASE Guo, Suo MD; Xia, Lan MD; Hu, Rong BS; Wang, Jing MD; Yang, Peizeng MD, PHD Retina 45(1):p 79-87, January 2025 120° Widefield SS-OCTA showed that VKH patients with duration of >24 months exhibited severe ischemia in LMVC. The vessel density of LMVC may serve as a diagnostic biomarker of irreversible complications. https://journals.lww.com/retinajournal/abstract/2025/01000/vascular_changes_and_irreversible_complications_in.11.aspx #retina

IMPACTS OF POSTERIOR STAPHYLOMA ON PARAPAPILLARY MICROVASCULATURE AND ATROPHY IN HIGH MYOPIC EYES A Matched Cohort Study With Optical Coherence Tomography Angiography Chen, Yanhui MD; Hui, Yan-Nian MD; Xing, Xiaoli MD; Rong, Hua MD; Bai, Yang MD; Li, Haoru MD; Mi, Baoyue MD; Guo, Xingyi MD; Wei, Ruihua MD, PhD Retina 45(1):p 61-71, January 2025 This study discovered that posterior staphyloma, a condition in high myopia, is linked to parapapillary atrophy and microvasculature dropout. These findings provide insight on how posterior staphyloma impacts parapapillary structures and microvasculature in high myopia. https://journals.lww.com/retinajournal/abstract/2025/01000/impacts_of_posterior_staphyloma_on_parapapillary.9.aspx #retina

EYE SHAPE DEFORMITY PREDICTS MYOPIC MACULOPATHY PROGRESSION AMONG HIGHLY MYOPIC INDIVIDUALS A 4-Year Longitudinal Study Li, Cong MD; Wu, Huawang MD, PhD; Xiao, Ou MD, PhD; Xiong, Ruilin MD, PhD; Guo, Xinxing MD, PhD; Chen, Yanxian MD, PhD; Yin, Qiuxia MPH; He, Mingguang MD, PhD; Li, Zhixi MD, PhD Retina 45(1):p 52-60, January 2025 Using 4-year longitudinal data, the authors observed that highly myopic individuals with eye shape deformity had myopic maculopathy progression more frequently than those with nondeformed eye shape. Eye shape deformity identified from three-dimensional magnetic resonance imaging is a novel predictor for myopic maculopathy progression, equally as important as axial length. https://journals.lww.com/retinajournal/abstract/2025/01000/eye_shape_deformity_predicts_myopic_maculopathy.8.aspx #retina

QUANTIFICATION OF CAPILLARY BLOOD FLOW SPEEDS IN DIABETIC RETINOPATHY USING VARIABLE INTERSCAN TIME ANALYSIS OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY Hwang, Yunchan SM; Takahashi, Hiroyuki MD; Won, Jungeun PhD; Yaghy, Antonio MD; Marmalidou, Anna MD; Kaiser, Stephanie M. BA; Jamil, Muhammad Usman MD; Baumal, Caroline R. MD; Waheed, Nadia K. MD; Fujimoto, James G. PhD Retina 45(1):p 35-43, January 2025 Variable interscan time analysis optical coherence tomography angiography can measure a quantitative biomarker for capillary blood flow speed in diabetic retinopathy and the association with vessel density in different capillary plexuses. Deep capillary plexus blood flow speed increases in diabetic retinopathy compared with normal eyes, although capillary density decreases. https://journals.lww.com/retinajournal/abstract/2025/01000/quantification_of_capillary_blood_flow_speeds_in.6.aspx #retina #MIT #NEEC

MACULAR HOLE SURGERY AND RETINAL TECTONICS The Impact of Internal Limiting Membrane Peeling Size on Tangential Retinal Displacement Pellegrini, Marco MD; Adamo, Ginevra MD; Vivarelli, Chiara MD; Bizzarri, Alice BSE; Mondin, Riccardo; Talli, Pietro Maria MD; Nasini, Francesco PhD; Giannaccare, Giuseppe PhD; Mura, Marco MD Retina 45(1):p 23-29, January 2025 Pars plana vitrectomy with internal limiting membrane peeling for macular hole is associated with a displacement of the central macula toward the optic disk. A larger peeling results in a greater retinal displacement, possibly improving the anatomical success rates. https://journals.lww.com/retinajournal/abstract/2025/01000/macular_hole_surgery_and_retinal_tectonics__the.4.aspx #retina

SPECTRAL-DOMAIN OPTICAL COHERENCE TOMOGRAPHY INSIGHTS INTO IDIOPATHIC EPIRETINAL MEMBRANE SURGERY OUTCOMES Mansilla, Raquel MD; Bande, Manuel F. MD, PhD; Mera, Purificación MD; Ruiz-Oliva, Francisco MD, PhD; Marticorena, Joaquin MD, PhD; Blanco-Teijeiro, María José MD, PhD Retina 45(1):p 14-22, January 2025 This study evaluates the prognostic value of a classification system based on ectopic inner foveal layers and other anatomical variables in idiopathic epiretinal membrane surgery in a large cohort of patients, guiding individualized treatment strategies. https://journals.lww.com/retinajournal/abstract/2025/01000/spectral_domain_optical_coherence_tomography.3.aspx #retina

OPEN ACCESS Article THREE-DIMENSIONAL HILL OF VISION OF RETINAL SENSITIVITY IN PARTICIPANTS WITH X-LINKED RETINITIS PIGMENTOSA UNDER SCOTOPIC AND MESOPIC CONDITIONS Yaghy, Antonio MD; Alibhai, A. Yasin MD; De Pretto, Lucas R. PhD; Curtiss, Darin PharmD; Birch, David G. PhD; Waheed, Nadia K. MD MPH Retina 45(1):p 7-13, January 2025 Traditional 2D heat maps are limited compared with 3D hill of vision (HOV) plots, which offer comprehensive visualization of retinal sensitivity patterns. This study explores the utility of HOV analysis in assessing retinal sensitivity in patients with XLRP using scotopic cyan, scotopic red, and mesopic microperimetry. https://journals.lww.com/retinajournal/fulltext/2025/01000/three_dimensional_hill_of_vision_of_retinal.2.aspx #retina @OCT_Waheed