The International Arabic Journal of Antimicrobial Agents

19/06/2022

Antibiogram of bacterial isolates from clinical specimens during 2018-2020 at Al-Aqsa hospital, Gaza, Palestine

http://imed.pub/ojs/index.php/IAJAA/article/view/2403

The increased resistance of microorganisms to widely prescribed antibiotics in current medical practice has become a major challenge. Healthcare-associated infections (HAIs) are complications of healthcare and linked with high morbidity and mortality. This study aims to investigate the susceptibility pattern of bacteria isolated from different bacterial infections to commonly used antimicrobials from Al-Aqsa hospital in Gaza Strip, Palestine.

03/06/2022

http://imed.pub/ojs/index.php/IAJAA/article/view/2405

Objective: Emergence of COVID-19 infection and its persistence globally for three years in a row (2020-2022) entailed several modifications in healthcare services, among which drug prescribing was an important outcome. This review aims to highlight changing trends in azithromycin prescribing during pandemic years.

Methods: PubMed database was systematically searched for combinations of the following keywords: Antibiotics; Antimicrobial resistance; Azithromycin; COVID-19.

Results: A total of 12 articles were included in this review. All included studies demonstrated a notable increase in azithromycin consumption during COVID-19 pandemic in Spain, Brazil, USA, India, Croatia, and Jordan. Healthcare systems worldwide should be prepared to address anticipated outcomes of increased azithromycin use particularly possible changing trends in azithromycin resistance, and systemic side effects of the drug.

Impact Of COVID-19 Pandemic On The Pattern Of Azithromycin Prescribing; A Review Authors Najla Dar-Odeh University of Jordan Osama Abu-Hammad Nebras althagafi Shaden Abu-Hammad Rawah Eshky Ismail Abdouh Mona Aboelnagga Abdalla Abu-Hammad DOI: https://doi.org/10.3823/866 Keywords: Antibiotics, Antimi...

19/05/2022

The International Arabic Journal of Antimicrobial Agents: Antimicrobial Susceptibility Pattern and Virulence Genes Detection in Citrobacter freundii Isolated from Patients of a Tertiary Care Hospital, Bangladesh

http://imed.pub/ojs/index.php/IAJAA/article/view/2397



Citrobacter freundii is an infrequent hospital acquired pathogen to cause different types of disease in clinical settings. This pathogen is associated with wide range of infections causing unpredictably high mortality rate of 30-60%. Separation of this pathogen in health care settings is escalating and multidrug resistant strains are emerging. Therefore, this study aimed to detect antimicrobial resistance pattern and virulence genes among the isolated C. freundii.

Antimicrobial Susceptibility Pattern and Virulence Genes Detection in Citrobacter freundii Isolated from Patients of a Tertiary Care Hospital, Bangladesh Antimicrobial susceptibility pattern and virulence genes detection in Citrobacter freundii Authors Asma Rahman Department of Microbiology, Dhaka M...

11/04/2022

Co-infection in patients with COVID-19 in Tripoli Northern Lebanon: germs involved and antibiotic sensitivity profile.

A considerable proportion of patients hospitalized with coronavirus disease 2019 (COVID-19) acquired bacterial infections. The aim of this study was to investigate the etiology and antimicrobial resistance of bacterial co-infection for more informed antimicrobial treatment.

http://imed.pub/ojs/index.php/IAJAA/article/view/2395

Co-infection in patients with COVID-19 in Tripoli Northern Lebanon: germs involved and antibiotic sensitivity profile. Authors Moustapha Khodor Laboratory of Nini Hospital Monzer Hamze Hassan Mallat Zahia Chahine George Chalouhi Marcel Achkar Nadim Azar DOI: https://doi.org/10.3823/864 Keywords: COV...

03/04/2022

http://imed.pub/ojs/index.php/IAJAA/article/view/2393

Objective: nowadays resistant bacteria represent worldwide a public health problem leading in some cases to a stalemate without any possible treatment. Therefore early detection and identification of carbapenemase producing gram-negative bacteria (GNB) is of crucial importance. Consequently we conducted a study in a tertiary care hospital to analyze the resistance phenotype of the carbapenem resistant GNB (CRGNB).

Carbapenemase typing and resistance profile of enteric bacteria isolate with reduced sensitivity to carbapenems in a Lebanese tertiary care center Authors Alexander Malek Saint Joseph University, Faculty of Medicine, Hotel Dieu de France, Beyrouth, the Lebanon Josselin Abi Chebl Saint Joseph Univers...

07/03/2022

The Effect of Vitamin D treatment on COVID 19- Patients, an Inverted Propensity Score Weighting (IPSW), and Inverted Probability of Treatment Weighting (IPTW) Analyzed Study:

Vitamin D3 (1,25(OH)2 cholecalciferol) as a treatment for COVID 19 patients is being disputed, and a clear clinical benefit is not being confirmed.

http://imed.pub/ojs/index.php/IAJAA/article/view/2391

The Effect of Vitamin D treatment on COVID 19- Patients, an Inverted Propensity Score Weighting (IPSW), and Inverted Probability of Treatment Weighting (IPTW) Analyzed Study Authors Jamal Wadi Al Ramahi Office 11, The Medical Center, Jordan Hospital and medical Center. 29 Adeeb Wahbeh StreetAmman -....

17/01/2022

The International Arabic Journal of Antimicrobial Agents: Physico-chemical and microbiological studies on Jordanian Honey and propolis as potential self-preserving pharmaceutical systems.

The aim of this project was to study the physico-chemical and antimicrobial properties of Jordanian honey and propolis in order to determine their potential as pharmaceutical preservation systems. This study undertook a physico-chemical analysis of several Jordanian honeys and one propolis type, in order to evaluate several physico-chemical properties including, pH and free acidity, moisture content, ash content and HydroxyMethylFurfural content in three honey samples, and total flavonoid content in the propolis sample.

The antimicrobial activity of honey and propolis samples was then evaluated by determining the minimum inhibitory concentration (MIC) against Staphylococcus aureus ATCC 6538, Escherichia coli ATCC 8739, Pseudomonas aeruginosa ATCC 9027 and Candida albicans ATCC 10231. Subsequently, Honey 1 (H1) was selected for further study and combined with propolis to test their potential synergistic activity. Finally, a preservative effectiveness test was conducted in order to assess the possibility of using honey and propolis as natural preservatives in aqueous dosage forms, such as syrups.

The results of this study showed that all the tested honey samples and propolis possessed significant antimicrobial activity against the standard test microorganisms, and that honey with propolis exhibited synergistic activity that enhanced their antimicrobial activity and resulted in up to 90% reduction in their MIC values. This study also confirmed that honey and propolis could be used as a natural preservative system for pharmaceutical formulae. Our results reveal the possibility of using honey-propolis mixtures as natural preservatives in oral aqueous pharmaceutical dosage forms and other local application products.



http://imed.pub/ojs/index.php/IAJAA/article/view/2389

Physico-Chemical and Microbiological Studies on Jordanian Honey and Propolis as Potential Self-Preserving Pharmaceutical Systems Authors Ibrahim SI Al-Adham Department of Pharmaceutics & Pharmaceutical Technology, Faculty of Pharmacy & Medical Sciences, University of Petra, Amman, Jordan. Najah Al-M...

11/11/2021

Kingella kingae and Neisseria meningitides are gram-negative bacteria, causing several life-threatening diseases and considered as opportunistic pathogens in the upper respiratory tract of healthy carriers. The detection of these both bacteria species is difficult in routine culture methods.



http://imed.pub/ojs/index.php/IAJAA/article/view/2387

17/09/2021

Antimicrobial resistance of bacterial isolates from the clinical and hospital environment in Gaza Strip, Palestine: A review over 20-year.

Antimicrobial resistance is a serious threatening problem associated with high morbidity and mortality. The majority of pathogenic bacteria show multiple drug resistance patterns. Thus, treatment of infections caused by those bacteria become ineffective. This paper evaluates, investigates, and discusses the existing situation of antimicrobial resistance in Gaza Strip, Palestine.



http://imed.pub/ojs/index.php/IAJAA/article/view/2386

Antimicrobial resistance of bacterial isolates from the clinical and hospital environment in Gaza Strip, Palestine: A review over 20-year Abdelraouf A. Elmanama Department of Medical Laboratory Sciences Faculty of Health Sciences Islamic University of Gaza, P .O. Box 108, Gaza Strip, Gaza, State of....

25/07/2021

Emerging ceftazidime-avibactam resistance against carbapenem resistant Escherichia coli and Klebsiella pneumoniae in Lebanon

Ceftazidime-avibactam (CZA) has been introduced as a novel drug to essentially combat the rising trends of carbapenem resistant Enterobacteriaceae. In the absence of in vitro data about the activity of this drug against carbapenem resistant (CR) Escherichia coli and Klebsiella pneumoniae in Lebanon, this study was warranted.



http://imed.pub/ojs/index.php/IAJAA/article/view/2385

Emerging ceftazidime-avibactam resistance against carbapenem resistant Escherichia coli and Klebsiella pneumoniae in Lebanon Ghena M Sobh Department of Pathology and Laboratory Medicine, American University of Beirut, Medical Center, Beirut, Lebanon Abdul Karim El Karaaoui MD, Department of Patholog...

30/05/2021

A case study of COVID-19 in the Arab Middle East and North Africa with a focus on Jordan during the year 2020

This article aims to provide a model by using cumulative cases for SARS-CoV-2 (Severe acute respiratory syndrome coronavirus 2) outbreak in most major countries with focusing on the Jordanian experience and response in combating COVID-19.

On March 2nd, 2020, Jordan reported the first confirmed cases of COVID‐19. Although, Jordan was among the first countries to implement highly strict preventive and control measures, the outbreak started around 1st October, 2020 (7 months later), after that there was a significant increase in the number of confirmed cases.

However, there are always opportunities to learn from the global experience to improve the current national strategy.



http://imed.pub/ojs/index.php/IAJAA/article/view/2384

A case study of COVID-19 in the Arab Middle East and North Africa with a focus on Jordan during the year 2020 Maen A. Addassi 30 Degree DOI: http://dx.doi.org/10.3823/857 Abstract This article aims to provide a model by using cumulative cases for SARS-CoV-2 (Severe acute respiratory syndrome coronav...

08/05/2021

http://imed.pub/ojs/index.php/IAJAA/article/view/2382

The study aims to evaluate the antibacterial activity of Trigona honey against S. pneumonia. Methods: The effect of Trigona honey on S. pneumonia investigated using agar well diffusion, MIC, MBC, biofilm formation and RT-qPCR.

Evaluation of antimicrobial and antibiofilm activities of stingless bee Trigona honey (Malaysia) against Streptococcus pneumoniae Mohammad A. Alkafaween Faculty of Health Sciences; Universiti Sultan Zainal Abidin, Terengganu, Malaysia. Hamid A. Nagi Al-Jamal Abu Bakar Mohmd Hilmi DOI: http://dx.doi....

24/04/2021

Resistance of Uropathogens at Governmental Hospitals in the Gaza Strip/Palestine

Urinary tract infection is a public health problem worldwide. E. coli and klebsiella are among the main etiologic for UTI in Gaza Strip. The growing variations in resistance among uropathogens to antimicrobials is multifactorial and varies globally. It greatly reduces/limits or complicate treatment option.




http://imed.pub/ojs/index.php/IAJAA/article/view/2383

28/03/2021

http://imed.pub/ojs/index.php/IAJAA/article/view/2381

The purpose of this study was to investigate antibacterial activity of three varieties of Malaysian honey; Tualang honey (TH), Gelam honey (GH), and Acacia honey (AH) against Escherichia coli.

The minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of the honey samples against E. coli were determined by the broth microdilution assay in the presence and absence of catalase enzyme. The mode of inhibition of honey samples against E. coli was investigated by the effect of time on viability. Impacts of the honeys on the expression profiles of the selected genes of E. coli were examined using RT-qPCR analysis.