Times of Pharma

14/08/2023

https://www.pharmacistspharmajournal.org/2023/08/b-pharma-degree-course-subjects-thought.html

B Pharma Degree Course Subjects thought in Degree Course

05/07/2023

https://timesofpharma.com/high-cholesterol-treatment/

Treatment for high cholesterol is based on the underlying root cause if the increased high cholesterol is due to any drug or disease condition

11/06/2023

https://timesofpharma.com/helicobacter-pylori/

Very important health information

Helicobacter Pylori the bacteria that stay alive in gastric hydrochloric acid the bacterial infection that causes stomach ulceration & cancer

19/03/2023

https://timesofpharma.com/usfda-483-detail-information/

483 observation of USFDA all observations during facility inspection are not mentioned in 483 form issued by USFDA 483 Detail information

16/01/2023

Clean Room Validation Microbial Count Limits method settle plate contact plate viable bacterial fungal count limits frequency of validation. Classification of clean rooms in pharmaceutical manufacturing companies is part of validation activity, a clean room is designed to provide the desired level of clean grade environment. but it's rated only to a particular grade after it is validated that the clean room is providing the desired level of particle count....

Clean Room Validation Microbial Count Limits method settle plate contact plate viable bacterial fungal count limits frequency of validation. Classification of clean rooms in pharmaceutical manufacturing companies is part of validation activity, a clean room is designed to provide the desired level o...

13/01/2023

Metal detector system to eliminate metal particle containing tablets during manufacturing. Question: How to remove metal particles if any which might be getting generated during manufacturing due to wear and tear of machines. Answer: Source for Metal particles in a tablet dosage form may be one of following. Raw material, Defective equipment, like broken sieve mesh, compression machine wear and tear....

Metal detector system to eliminate metal particle containing tablets during manufacturing online metal detector

13/01/2023

Question: How to solve this problem of Capping in tablets, we are getting consistent problem of capping in our Paracetamol tablets where paracetamol is 500 mg and other excipients like starch, and talcum, and aerosil, magnesium stearate etcetera comprises about 60 mg. The Total weight of the tablet is 560 mg. It is round beveled and 13.5 mm round. Answer: …...

How to solve problem of Capping in tablets getting consistent problem of capping in our Paracetamol tablets where paracetamol is 500 mg

07/01/2023

it's a virus

05/01/2023

Documentation control Standard operating procedure is the originator of the documents, in a standard operating procedure instructions are provided for doing an activity. In the same SOP a format is provided for monitoring the parameters of the activity with time etc. This is there in the SOP at the end of the SOP as annexure, these are called formats. Just as the SOP is required to have a SOP number these formats too are required to have the number for controlling the documentation....

Documentation control Standard operating procedure is the originator of the documents, in a standard operating procedure instructions are provided for doing an activity. In the same SOP a format is provided for monitoring the parameters of the activity with time etc. This is there in the SOP at the....

03/01/2023

How to reduce cholesterol? Why medicines are used to Lower high cholesterol ? Which medicines are given to treat hypercholesterolemina ? Higher level of cholesterol in body is very dangerous as it may block coronary arteries and may cause heart failure, cholesterol tend to form fatty plaques in veins and arteries, which when dislodged may occlude blood flow, if the artery that get occlusion is one that supply blood to brain in is very serious situation it can cause stroke, by virtue of occlusion of blood flow to brain....

Treatment for High Cholesterol Medicine that reduce cholesterol levels Hyoercholestelemia treatment with drug available protect heart

02/01/2023

Do you know that there are some diseases which can only be treated by injecting live bacteria and virus at the point of disease. Bladder Cancer treatment with live atenuated microorganisms Bacillus Calmette-Guerin (BCG). Gene Therapy assited by live virus vector, Novel Drug Delivery System. One of such disease is bladder cancer which is treated by injecting live bacterial inoculum in to bladder....

Diseases which can only be treated by injecting live bacteria and virus at the point of disease Bladder Cancer treatment with BCG Gene Therapy

02/01/2023

We have seen Millions of people have died in Corona Virus Pandemic which started in 2019 in China and after claiming life of millions of people, through various mutations like Delta Omicron and so on, the Corona Virus is still a deadly virus infection.medicines like Remdisavir and Interferons and Monoclonal antibodies treatment plasma Therapy ect are still not yielding the results as it's with other viral infections which are controlled with medicine and antiviral drugs....

We have seen Millions of people have died in Corona Virus Pandemic which started in 2019 in China and after claiming life of millions of people, through various mutations like Delta Omicron and so on, the Corona Virus is still a deadly virus infection.medicines like Remdisavir and Interferons and Mo...

31/12/2022

Novel drug Adstiladrin that delivers genes through a live virus vector, approved by USFDA for treatment of non-muscle invasive Bacillus Calmette-Guérin (BCG)-unresponsive bladder cancer. This month the US FDA has approved a novel drug, a gene therapy that makes use of a live virus (vector) which carries the gene and delivers it to the point where it is required to provide treatment....

Novel drug Adstiladrin that delivers genes through a live virus vector, approved by USFDA for treatment of non-muscle invasive Bacillus Calmette-Guérin (BCG)-unresponsive bladder cancer.

30/12/2022

Maintaining the integrity of data in pharmaceutical industry. What is data integrity How to Maintain data integrity in Pharmaceutical Industry Integrity is a principle of being truthful and honest towards the work and data generated through work by inculcating and practicing strong moral and ethical principles while doing work in an organization or as an individual. When it comes to data generated, gathered while manufacturing a medicine in a pharmaceutical company, it is expected that all data generated are honoring above principle, generated data is authentic, and reliable, and in event of challenged by any inspection authority it must prove its truthfulness and reliability....

Maintaining the integrity of data in pharmaceutical industry. What is data integrity How to Maintain data integrity in Pharmaceutical Industry Integrity is a principle of being truthful and honest towards the work and data generated through work by inculcating and practicing strong moral and ethical...

29/12/2022

Clean room in Pharmaceutical Manufacturing Facility Higher degree of cleanness is required in some places like pharmaceutical manufacturing and in healthcare and Space and computer chip manufacturing places. Particle contaminants are not just particles but they harbor bacterial as well as fungal and viral contaminants, therefore it is important to eliminate the particles from air in the core manufacturing area, Sterile injections are required to have almost no viable microbial and viral or fungal count in the filling and manufacturing area....

Modular Clean Room in Pharmaceutical Industry clean Room requirements in Pharmaceutical industry sterile pharmaceuticals mfg

28/12/2022

What is Clinical Trial Clinical Research. Clinical Trial Definition: It is study of safety and efficacy of a medicinal compound or a physical intervention practice (yoga) on healthy human volunteers, to conclude if the medicinal compound or a formulation or a drug can be used safely to mitigate or treat the disease condition or symptoms of underlying cause developed due to disease conditions or due to surgery or due to physiological disturbances, psychological disturbance (behavior)...

What is Clinical Trial Clinical Research. Clinical Trial Definition: It is study of safety and efficacy of a medicinal compound or a physical intervention practice (yoga) on healthy human volunteers, to conclude if the medicinal compound or a formulation or a drug can be used safely to mitigate or t...

25/12/2022

What is cholesterol why it is harmful/ dangerous when its level in body increases. Cholesterol has very important function in our body, it is required to forms membrane wall of cells in our body, and maintain cellular physical properties and integrity. Cholesterol is classified in three categories. 1)High Density Lipoprotein (HDL) 2)Low Density Lipoproteins (LDL) 3)Very Low Density Lipoproteins. Low density cholesterol is in the form of liquid circulating in blood, and as and when its concentration or level in blood goes up, it has tendency to get deposited as solid plaque inside the blood vessels and capillaries through which it flows....

Total cholesterol less than 200 is optimal level and greater reading are considered as alarm of developing coronary heart diseases.

24/12/2022

I was asked today if I am a good Judge to identify if a market complaint is a fake. Or is it a genuine, to understand that there very important aspects that one must know are. Product history, knowledge about competitors product, and the ability to find out genuine root cause. If you can identify the root cause of a market complaint then you have opportunity to improve the defect....

pharma manufacturer must have system to handle market complaints identify root cause of Deviation Incidence if not drug is termed adulterated

23/12/2022

New anti-retroviral drug Lenacapavir approved by USFDA for treatment of multi drug resistant HIV 1 infection. On 22-Dec-2022 United States Food and Drug administration approved a new drug for treatment of HIV-1 infection, for patients where other drugs were developing drug resistance (Multi drug resistance). Name of Drug approved by the US FDA is Sunlenca which contains lenacapavir and is manufactured by Gilead Sciences....

New anti-retroviral drug Lenacapavir approved by USFDA for treatment of multi drug resistant HIV 1 infection

21/12/2022

Data Integrity_AwarenessDownload Data Integrity is very important aspect of pharmaceutical good manufacturing practices. We have provided here a presentation for training personnels in Pharmaceutical manufacturing company.

Data Integrity is very important aspect of pharmaceutical good manufacturing practices. We have provided here a presentation for training personnels in Pharmaceutical manufacturing company.

13/12/2022

Quality management system in a pharmaceutical manufacturing company What is quality management system QMS in pharma company? Following functions all together when driven together forms, every function is more or less interlinked or impacting other, therefore systematic operating of every function is important to achieve compliance and quality aspects as defined in guidelines of regulatory agencies across the world. Training of personnel....

Quality management system in a pharmaceutical manufacturing company What is quality management system QMS in pharma company

12/12/2022

What you should know for effective handling deviations in a pharmaceutical company Definition of Deviation: Any observed and non-observed departure of value or an event or procedure or action from set parameter, written and approved standards or acceptable limits or statements is called as deviation. If someone do not follow or finds a difference in what is done and what is in written instructions while manufacturing, sampling, storage of Raw material, sampling of raw as well as finished product, during testing of raw, bulk, and finished product, or packing material, by virtue of the requirement or by virtue of circumstances, such events are called as deviations....

Handling deviations in a pharmaceutical company Any observed and non-observed departure of value or an event or procedure or action from set parameter written and approved standards or acceptable limits or statements

11/12/2022

Novel drug Rebyota for treatment of Clostridioides difficile infection USFDA have approved first of its kind new drug for treatment of Clostridioides difficile infection. The drug is used as microbial inoculam in re**um, drug Rebyota is made from the f***l matter donated by healthy volenteers, it consists of microbial microbiota which help in supression of Clostridioides difficile bacteria. Thus protects individual from life-threatening disease....

USFDA approved new drug Rebyota for treatment of Clostridioides difficile infection used as microbial inoculam in colon, novel drug approval

07/12/2022

USFDA approves new drug that halts progression of Type 1 Diabetes. Type 1 diabetes is a very severe type of diabetes, type 1 diabetes patient’s pancreases produce very little of negligible amount of insulin which makes them diabetic, therefore patients affected with type 1 diabetes are required to take insulin injections throughout their lifetime. One of the painful part is that it affects children and youngsters who are diagnosed at younger age for type 1 diabetes mellitus....

USFDA approved the drug Tzield (teplizumab-mzwv) which can halt progression of type 1 diabetes from stage 2 to stage 3 protects patient’s pancreatic cells from getting destroyed by autoimmune disorder.

06/12/2022

How to handle market complaint in pharmaceutical industry? One of the prime objective of addressing the market complaints or product complaint received from user is to 1) Prevent any loss to patient due to malfunctioning or faulty product. 2) To maintain the quality of the product by learning the root cause of the defect and providing mitigation to it through corrective and preventive action so that the same kind of defect is not found in marketed product....

How to investigate handle market complaints

05/12/2022

Tablets dosage form different types of tablets dosage form manufactured Tablet is an oral dosage form in pharmaceutical dosage forms, it is one of widely acceptable and of very great importance. One can formulate a tablet with drug amount in the range of 0.01 mg to 500 to 600 mg for human dosage and up to 1 gm to 5 gm for veterinary dose....

Tablets dosage form different types of tablets dosage form manufactured classified as 1) application of the drug 2) Process of the Manufacturing 3) Special features of tablets (Sustained release, delayed release drugs, Osmotic controlled release tablets.)1) Oral 2) Sublingual buccal 3) Urethral, 4)....

17/12/2021

https://www.pharmacistspharmajournal.org/2021/12/sildenafil-reduces-risk-of-alzheimers.html

Alzheimer’s disease Dementia treatment with Sildenafil improve Alzheimer's Disease