MDedge Neurology

28/08/2022

More than half of patients with mild TBI and a negative head CT scan have not recovered completely 6 months after sustaining their injury, new data from the TRACK-TBI study shows.

"These results highlight the importance of improving care pathways for concussion, particularly from the emergency department."

27/08/2022

New research suggests that regular physical activity can help lower the risk of COVID-19 infection and its severity.

Regular physical activity may help lower the risk of COVID-19 infection and its severity.

27/08/2022

Polyneuropathy remains a common comorbidity among patients with COPD. Better screening strategies are needed to identify the condition and improve patients’ QoL, according to authors of a recent review.

Polyneuropathy remains a common comorbidity among patients with chronic obstructive pulmonary disease.

26/08/2022

A diet low in fat and copper and rich in fiber and zinc might benefit patients with comorbid migraine and IBS.

Key clinical point: A diet low in fat

26/08/2022

Did I hear that correctly? If something doesn’t make sense, it’s best to seek clarification as a “medical mondegreen” may have serious consequences.

Human communication can be flawed, and in medicine flawed communication can have consequences.

25/08/2022

It’s not the sitting part of sedentary behavior that potentially has the effect on dementia but what people are doing while sitting, according to results of large prospective cohort study. http://ms.spr.ly/6185jdKXh

Study finds that actively using a computer is linked with reduced risk.

25/08/2022

Older adults with may have up to 35% higher risk for dementia even before symptoms develop, new research suggests. http://ms.spr.ly/6187jjAXJ

Older adults with atrial cardiopathy may have up to 35% higher risk for dementia even before symptoms develop.

24/08/2022

The FDA has approved Abbott Laboratories’ new Proclaim Plus spinal cord stimulation system featuring FlexBurst360 therapy for the treatment of patients with chronic pain.

"With its ability to mimic natural patterns found in the brain, the Abbott BurstDR platform has been a game changer," said Dr. Steven Falowski.

24/08/2022

Study: Atomoxetine treatment safe, well tolerated and achieves target engagement in prodromal Alzheimer's disease.

Atomoxetine, approved for ADHD, can be repurposed as a safe and effective therapy for mild cognitive impairment and improves multiple biomarkers of Alzheimer's disease, according to this study.

23/08/2022

Increased dietary niacin intake may have a beneficial effect on migraine outcomes.

Key clinical point:

23/08/2022

A dose of 120 mg galcanezumab monthly was effective and well tolerated in patients with episodic migraine.

Key clinical point

22/08/2022

The key to reducing migraines in some patients could be an unexpected type of surgery.

Key clinical point:

22/08/2022

New research provides novel insight into how mindfulness alters pain-related activity in the brain, in findings that point to more targeted pain management.

Those who completed a mindfulness-based stress reduction program had a reduction in a brain signature linked to the sensory intensity of pain.

21/08/2022

Part of solving complex problems is allowing all stakeholders’ voices to be heard.

Part of solving complex problems is allowing all stakeholders' voices to be heard.

21/08/2022

Centenarians are the antithesis of the misguided belief that the older you get, the sicker you get. Quite the opposite occurs.

Between 1980 and 2019, the share of American centenarians grew faster than the total population.

20/08/2022

For the 2022 Physicians Behaving Badly Report, more than 1,500 physicians shared how often they see fellow doctors misbehaving in person or on social media, and shared some of the worse behavior they’ve seen.

Bullying or harassing clinicians and staff was the runaway winner, with 86% of respondents saying they'd seen this type of behavior at work at some time.

20/08/2022

740 million people in the world live with tinnitus.

The global prevalence of tinnitus likely will increase as the population grows older, according to researchers.

19/08/2022

Since 1947, Howard Tucker, MD, has witnessed major changes in health care, from President Truman proposing a national health care plan to Congress to the present day existence of the EMR. After 75 years, Tucker's love of practicing neurology endures.

Residents say to me all the time, "55-year-old man, CAT scan shows ..." I have to say to them: "Slow down. Let's talk about this first."

19/08/2022

Enhancing life satisfaction is a possible way to enhance , , and processing speed or protect against their decline.

Clinical science can profit from exploring cognitive-behavioral therapies to improve adults' cognitive function or life satisfaction.

18/08/2022

VZV infection may activate dormant HSV-1, leading to neuroinflammation and accumulation of Alzheimer’s disease–related proteins in the brain, new research suggests.

"Our results suggest one pathway to Alzheimer's disease, caused by a VZV infection which creates inflammatory triggers that awaken HSV in the brain."

18/08/2022

. with an informal journal club regarding an interesting new study that tries to answer the big question of “what’s going on with cognitive fatigue?”.

Welcome to Impact Factor, your weekly dose of commentary on a new medical study. I'm Dr. F. Perry Wilson of the Yale School of Medicine.

17/08/2022

In summer 2022, we have the least-wanted sequel in modern history – Polio II: The Return. http://ms.spr.ly/6187jnq9U

Cracks in herd immunity have allowed polio to return.

16/08/2022

More and more physicians are being wooed by private equity firms that want to buy their practices. While the potential profit may seem alluring, physicians have mixed feelings as to whether this will be a boon or a disappointment.

Private equity firms expand practices to receive more favorable reimbursements and achieve economies of scale.

16/08/2022

Two children taking the gene therapy drug onasemnogene abeparvovec for SMA have died from acute liver failure, according to a statement issued by the drug’s manufacturer.

These are the first known fatal cases of acute liver failure associated with the drug, which the company notes was a known side effect included in the product label.

15/08/2022

Screening for atrial fibrillation with wearable devices is cost effective, when compared with either no screening or screening using traditional methods, a new study concludes.

Screening for atrial fibrillation using wrist-worn devices is cost effective, compared with no screening or screening for AFib using traditional methods.

15/08/2022

Dietary salt substitutes not only lower BP but also have a clear impact on hard clinical endpoints, lowering the risk of MI, stroke, and death from all causes and CVD, a meta-analysis shows.

The blood pressure-lowering effects of dietary salt substitutes have a clear protective effect on hard clinical outcomes, leading to a reduction in heart attack, stroke, and death.

14/08/2022

As more than 100K COVID-19 cases and hundreds of deaths from the infection continue to be reported daily, experts fear a second wave of illnesses from long COVID which already affects up to 23 million Americans.

“If we conservatively assume 100 million working-age adults have been infected, that implies 10 to 33 million may have long COVID.”

14/08/2022

COVID-19 infection may result in long-term neurological symptoms and possibly even future neurodegeneration. These concerns have prompted efforts to identify biomarkers that can help track and monitor neurological complications of COVID-19.

13/08/2022

Hundreds of millions of people worldwide have low back pain. New research suggests the solution for the world’s leading cause of disability may lie in fixing how the brain and the body communicate.

New research debuts a novel effective treatment for chronic pain.