18/09/2019
Does anyone here familiar about the picture below? Too much stress, gadgets, works can lead you to this! 👇
How does glutathione+NAC can help and prevent the paralysis of the nerve?
Let's take time to read the clinical studies of GLUTATHIONE +NAC to our health.
N‐acetyl‐cysteine (NAC) is a glutathione substrate that can readily be taken up by neurons. Glutathione in neurons acts as a free radical scavenger, protects the cytochrome oxidase system in mitochondria, and improves neuronal regeneration. It is hypothesized that NAC may thus improve neuronal survival by blocking entry into cell cycle, improving free radical surveillance, and preserving mitochondrial function.NAC has been studied in nerve transection models and has been shown to reduce neuronal and glial cell death, preserve mitochondrial architecture and have greater regeneration of neurons over corticosteroids.
This study demonstrated that NAC facilitated facial nerve recovery with improved functional and EMG outcomes in the setting of crush injury. This was present at two weeks indicating that it may facilitate a more rapid recovery as well. Based on the findings of this study, further investigation is warranted to elucidate the histopathology findings with the use of NAC in the setting of crush injury and to evaluate its efficacy compared to and in conjunction with other neuro‐protective treatment modalities.
Presented at American Neurotology Society/Combined Otolaryngology Spring Meeting, April 24–25, 2015, Boston, MA.
Funding: University of Miami Department of Otolaryngology
