Conexiant

11/06/2024

Vi**ra, known for enhancing blood flow, shows promise in boosting brain health to combat vascular dementia. The OxHARP trial found sildenafil improved cerebrovascular function in individuals with cerebral small vessel disease.

Recent trial showed sildenafil improved cerebrovascular function in small vessel disease, potentially aiding in the prevention of vascular dementia.

10/06/2024

An FDA advisory committee has unanimously recommended the approval of donanemab, a drug shown to significantly slow cognitive decline in patients with early Alzheimer’s. This recommendation follows promising results from the Phase 3 TRAILBLAZER-ALZ 2 trial. If the FDA follows through, donanemab could soon become a new treatment option for those with mild cognitive impairment and mild dementia due to Alzheimer’s. Stay tuned for updates!

An FDA advisory committee has recommended the approval of donanemab for treating Alzheimer’s disease, citing effectiveness in slowing cognitive decline based on positive Phase 3 trial results.

06/06/2024

Intriguing new research indicates that women's cognitive abilities, like reaction speed and accuracy, may be enhanced during menstruation. This could have important implications for understanding injury risk and optimizing performance throughout the menstrual cycle.

New research suggests that women's cognitive performance, including reaction times and accuracy, may improve during menustration.

05/06/2024

NYU Langone Health experts warn of new, highly contagious fungal infections emerging in the U.S., including a sexually transmitted ringworm strain. Health care providers should be alert for unusual rashes on the face, limbs, groin, and feet, as these infections can be difficult to treat.

Health care providers are warned of new, highly contagious, and hard-to-treat fungal infections, including sexually transmitted ringworm, now emerging in the U.S.

04/06/2024

In a setback for those seeking novel treatments for PTSD, an FDA advisory committee has recommended against approving M**A-assisted therapy. The decision came despite clinical trials showing significant improvements in PTSD symptoms when M**A was used in conjunction with psychotherapy.

The committee raised concerns about safety, potential abuse, and the adequacy of risk mitigation strategies. While some researchers and patients advocated for approval, citing life-changing results, others emphasized the need to prioritize public safety. The FDA's final decision will determine the future of this controversial treatment approach.

An FDA advisory committee recommended against the approval of M**A for treating PTSD, citing concerns over safety and other potential risks.

03/06/2024

Exciting news from ASCO 2024! The LAURA trial found that the targeted therapy osimertinib significantly improves outcomes for lung cancer patients with a specific genetic mutation (EGFR) whose cancer has not spread but cannot be surgically removed.
Patients who received osimertinib after chemo and radiation went much longer without their cancer growing or spreading compared to those who got placebo (median 39 months vs 6 months). Osimertinib also led to fewer cases of the cancer spreading to the brain.

This marks a big step forward in treating this group of patients more effectively. The researchers will continue to track participants to see if osimertinib also improves survival.

Osimertinib improved progression-free survival in patients with unresectable stage III EGFR-mutated NSCLC that has been treated with chemoradiotherapy—and may be a new standard of care for this popula...

03/06/2024

Exciting news! The American Society of Clinical Oncology and the American Cancer Society have joined forces to create one of the largest and most comprehensive online resources for credible cancer information. This collaboration, spearheaded by ASCO CEO Clifford A. Hudis, MD, and American Cancer Society CEO Karen E. Knudsen, MBA, aims to make it easier for patients to access authoritative cancer information online. The resource will be available for free to the public on cancer.org. This partnership is a significant step forward in providing reliable and accessible information to those affected by cancer.

Clifford A. Hudis, MD, and Karen E. Knudsen, MBA: An ASCO-American Cancer Society Partnership to Benefit Patients 2024 ASCO Annual Meeting Advertisement Clifford A. Hudis, MD, CEO of the American Society of Clinical Oncology (ASCO), and Karen E. Knudsen, MBA, CEO of the American Cancer Society, disc...

01/06/2024

New research presented at the Endocrine Society's annual meeting (ENDO 2024) found that higher blood testosterone levels are associated with a lower risk of developing type 2 diabetes in men under age 65 who are overweight or obese.

Study finds higher blood testosterone levels are linked to a lower risk for type 2 diabetes in men under 65.

01/06/2024

The FDA is undergoing a major reorganization, its largest in recent history. A new unified Human Foods Program will be created in October to improve regulation of food supply chains and agricultural products.

The FDA will restructure its food division in October to create a unified Human Foods Program, aiming for greater efficiency and agility in overseeing human food supply chains and agricultural products.

01/06/2024

Research shows the age when a man becomes a father may impact his cardiovascular health. A study found fathers, particularly those under 25 when their oldest child was born, had poorer overall cardiovascular health scores compared to older fathers and non-fathers. The findings underscore fatherhood as an important social determinant of health, with implications for targeted interventions to improve health outcomes among young dads and men of color.

Research shows young fathers face greater cardiovascular risks and highlights racial disparities in health outcomes.

29/05/2024

New research in the Journal of the American Heart Association reveals a link between optimal heart health and slower biological aging. The study found that following the American Heart Association's Life's Essential 8 guidelines for cardiovascular health may reduce the risk of heart disease, stroke, and death, especially in individuals with a genetic tendency towards faster aging. The lead author emphasizes the importance of healthy lifestyle factors like diet, physical activity, sleep, and managing weight, cholesterol, blood sugar, and blood pressure.

New research reveals that optimal cardiovascular health may slow down biological aging and reduce the risk of cardiovascular disease and mortality.

29/05/2024

We're excited to announce the launch of Conexiant! Learn more about our evolution and future endeavors here: https://bit.ly/conexiantpr

28/05/2024

A recent study found that certain blood pressure medications may increase the risk of eczema in older adults. The study, which analyzed data from over 1.5 million UK patients, showed that diuretic drugs and calcium channel blockers had the strongest association with eczematous dermatitis. ACE inhibitors and β-blockers had a smaller effect. Researchers suggest that switching medication classes may help manage eczema symptoms in this population.

A new study links antihypertensive medications to eczematous dermatitis in older adults, suggesting that switching medication classes may help manage symptoms.

28/05/2024

A recent study has found a potential link between tattoos and a 20% increased risk of developing lymphoma. Researchers emphasize the need for safer tattoo ink production and further investigation into the long-term health effects of tattoos. The study highlights the importance of being aware of potential health risks associated with tattoos and seeking medical attention if any symptoms related to tattoos arise.

Study suggests tattooed individuals have a 20% higher risk of developing lymphoma, highlighting the need for further research on the long-term health effects of tattoos and safer ink production.

24/05/2024

In a 7-4 vote, an FDA advisory panel has recommended against the approval of icodec, a once-weekly basal insulin injection for type 1 diabetes. The panel concluded that the treatment's benefits do not outweigh its risks for improving glycemic control in adults with T1D. This decision comes despite the European Medicines Agency and Canada approving its medical use earlier this year. The FDA usually follows the panel's advice, suggesting that concerns about icodec's risk-benefit profile ultimately outweighed the findings of its Phase 3 clinical trials.

FDA advisory panel votes against recommending approval of icodec, a once-weekly basal insulin injection, citing concerns over its risk-benefit profile.

23/05/2024

Exciting news in the fight against colorectal cancer: An FDA advisory panel has given a thumbs up to the Shield cfDNA blood test, which could offer a more convenient and less invasive screening method. The test, intended for people 45 and older at average risk, showed promising results in detecting colorectal cancer and precancerous lesions. With colorectal cancer being the second leading cause of cancer deaths in the U.S., this new test could help improve screening rates and catch the disease earlier, potentially saving thousands of lives each year.

By a vote of 8 to 1, the panel determined the test is safe for individuals who meet the criteria.

21/05/2024

A recent study has found that the ketogenic diet may speed up aging by inducing cellular senescence. Published in Science Advances, this research shows the need for personalized dietary interventions to mitigate potential risks. The study suggests that while the keto diet offers benefits like weight loss and metabolic improvements, it may also pose risks if not carefully managed. Researchers emphasize the importance of individualizing keto protocols to ensure safety and effectiveness.

Study reveals that ketogenic diets can induce cellular senescence, highlighting the need for personalized dietary interventions to mitigate potential risks.

17/05/2024

A recent study has unveiled significant disparities in military health care, showing how power dynamics and military rank influence physician care. High-ranking patients received more resources and had better outcomes compared to their lower-ranked counterparts. Explore the full findings and implications here:

Study reveals how military rank influences physician care, showing disparities in treatment based on power dynamics.

16/05/2024

Navigating epilepsy treatment during pregnancy presents unique challenges, requiring careful consideration to ensure the health and safety of both mother and baby. Our latest article highlights the new AAN/AES/SMFM guideline, offering comprehensive recommendations for antiseizure medication use in pregnancy. Discover key insights and strategies to optimize care for expectant mothers with epilepsy. Read more:

New AAN/AES/SMFM guideline provides recommendations for antiseizure medication use in pregnancy

15/05/2024

A recent study has found a connection between experiences of everyday and major discrimination and accelerated biological aging. Researchers analyzed survey and blood DNA methylation data from a large cohort of adults and discovered that individuals reporting higher levels of discrimination exhibited faster aging rates and older biological ages. The findings underscore the importance of interventions to promote healthy aging and address health disparities. Further research is needed to explore the pathways linking discrimination with biological aging and investigate potential protective factors.

https://conexiant.com/internal-medicine/articles/discrimination-linked-to-faster-aging/

14/05/2024

A simple oral rinse may provide a new method for early detection of gastric cancer, according to new findings. This approach could potentially revolutionize cancer screening and prevention. Read more about this study and its implications. https://www.conexiant.com/gastroenterology/articles/oral-rinse-could-provide-early-screening-for-gastric-cancer/

13/05/2024

New research reveals a link between persistent childhood sleep deprivation and increased risk of adult psychosis. The longitudinal study underscores the importance of adequate sleep during critical developmental periods for long-term mental health. Read more about the findings and their implications in our latest article. https://conexiant.com/family-medicine/articles/childhood-sleep-loss-may-boost-adult-psychosis-risk/

10/05/2024

Could a plant-based alkaloid treatment help people quit va**ng? A recent study reveals promising results for cytisinicline in va**ng cessation. Dive into the details of the ORCA-V1 Randomized Clinical Trial and see what the researchers found. 🍃🔬

https://conexiant.com/family-medicine/articles/botanical-aid-to-beat-vape-cravings/

10/05/2024

Are we underestimating the impact of ultra-processed foods on our health? A new study from the BMJ links high consumption of processed foods to increased mortality rates. This extensive research spans three decades and offers critical insights into dietary impacts on health. Learn more about which foods pose the greatest risks and how dietary quality can mitigate these effects. https://conexiant.com/family-medicine/articles/ultra-processed-foods-linked-to-higher-mortality/

09/05/2024

🔍 A new review sheds light on the serious issue of harassment within the ObGyn healthcare sector. Nearly 7 in 10 ObGyn trainees have faced sexual harassment, including coercion. This calls for an urgent reevaluation of current preventive measures and reporting systems in medical institutions.

https://conexiant.com/family-medicine/articles/obgyn-harassment-prevalence-exposed-in-revealing-review/

09/05/2024

Explore the latest study revealing crucial insights into cardiovascular, kidney, and metabolic syndrome stages among U.S. adults over the past decade. Understand the impact and the need for targeted healthcare interventions.

https://www.conexiant.com/cardiology/articles/alarm-bells-ckm-syndrome-engulfs-the-us-adult-population/

08/05/2024

In a detailed critique, experts have reviewed a recent JAMA study, which has been influential in discussions about drug price controls. The analysis points out significant methodological flaws and potential risks to patient health that could stem from misguided pricing strategies. For a deeper understanding of the implications, click here: 🔗 https://conexiant.com/internal-medicine/articles/new-brief-challenges-jama-study-on-drug-prices/

08/05/2024

🧠 Recent research investigates the role of brain connectivity in assessing the risk for cannabis use disorder (CUD). Employing advanced functional MRI techniques, the study examines differences in brain network dynamics that may influence susceptibility to CUD.

The analysis involved 94 patients, using the Cannabis Use Disorder Identification Test-Revised (CUDIT-R) to assess risk levels. Distinct patterns of brain connectivity were observed in at-risk individuals, suggesting potential targets for early intervention. The study provides a foundation for future research into pharmacological and neurostimulation treatments.

These insights could be crucial for professionals in addiction medicine and psychiatry, offering new avenues for preventive strategies in CUD.

🔗 For a deeper understanding and detailed analysis, read the full article here:

https://conexiant.com/family-medicine/articles/cannabis-use-disorder-risk-potentially-tied-to-brain-connectivity/

07/05/2024

MED3000, an FDA-approved over-the-counter gel, has demonstrated efficacy in treating erectile dysfunction according to recent clinical trials. This new treatment option could provide an alternative for patients who are unable to use traditional therapies.

🔗 Read the full article: https://conexiant.com/family-medicine/articles/otc-gel-shows-promise-for-erectile-dysfunction/

07/05/2024

Recent findings from a study published in JAMA Network Open suggest that olive oil may play a significant role in reducing dementia-related mortality. The research, encompassing data from over 90,000 health professionals tracked across 28 years, explores how dietary intake of olive oil impacts long-term cognitive health.

The study also examines the specific effects of replacing common dietary fats with olive oil. Are the benefits as significant as suggested? And how does olive oil consumption correlate with genetic and lifestyle factors?

For a deeper understanding of these important findings and their implications for dietary recommendations, the full article available:

Explore the latest research on how olive oil consumption may reduce dementia-related mortality, emphasizing key findings and dietary implications for cognitive health.