24/12/2019
Minimally Invasive Technique for Direct Measurement of Neonatal Hemodynamic Utilizing the COstatus Monitor
Background:The objective of this study is to establish feasibility of directly measuring cardiac output in a neonatal population using the COstatusMonitor (Transonic Systems, Ithaca, NY USA).Methods:The COstatus Monitor utilizes an extracorporeal loop attached to arterial and venous lines to measure cardiac output using ultrasound dilution. Injections of 1mL/kg of body temperature saline were injected into the loop. Up to two measurement sessions were performed daily for a maximum of four days for each patient.Results:Cardiac output was measured 54 times in 12 neonates with no adverse events. Infants ranged in weight (0.72 to 3.74 kg), gestational age (24 to 41.3 weeks), and day of life (1 to 13 days). The mean cardiac output was 0.43 L/min with a mean cardiac index of 197 mL/kg/min.Conclusions:Direct measurement of cardiac output by the COstatus monitor is feasible in a neonatal population. Minimal variance was exhibited for all parameters in consecutive measurements.