Asploro Open Access Publications (2025)

18/02/2025

Possible Adverse Effects (AEs) of Semaglutide (Ozempic) Administration for the Latest Investigation

Hiroshi Bando1,2iD*

1 Medical Research/ , Tokushima, Japan
2 Japan Low Carbohydrate Diet Promotion Association (JLCDPA), Kyoto, Japan

Diabetes Research: Open Access
Article Type: Commentary
DOI: https://doi.org/10.36502/2024/droa.6189
Diab Res Open Access. 2024 Nov 02;5(1):17-20

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Abstract
Semaglutide has been widely used in the treatment of type 2 diabetes (T2D) and obesity within medical and healthcare settings. Among its formulations, Ozempic has drawn attention for potential adverse effects (AEs). In a study involving 3,962 cases of obesity, the average data showed a weight reduction of 11.8%, a BMI decrease of 4.5 kg/m², and a reduction in waist circumference of 9.4 cm. One notable effect, termed “Ozempic tongue,” is characterized by altered taste sensitivity—such as sour, metallic, or bitter tastes—reported in approximately 6% of cases. These effects are not only considered AEs but are also linked to beneficial outcomes in weight reduction. Additionally, some users have reported changes in the appearance of the breasts, buttocks, and lips with Ozempic administration.

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Semaglutide has been widely used in the treatment of type 2 diabetes (T2D) and obesity within medical and healthcare settings. Among its formulations, Ozempic has drawn attention for potential adverse effects (AEs). In a study involving 3,962 cases of obesity, the average data showed a weight reduct...

18/02/2025

Asymptomatic Finding of Portal Vein Aneurysm

Manish Kumar1, Jashandeep Bajaj2, Muskaan Dhillon3, Kartik Goswami2*, Sanjeev Goswami4

1 College of Medicine, Jonelta Foundation School of Medicine, Philippines
2 College of Medicine, , Elk Grove, USA
3 College of Medicine, California Health Sciences university, Clovis, USA
4 Pulmonary and Critical Care Medicine, St. Joseph’s Medical Center, Stockton, USA

Asploro Journal of Biomedical and Clinical Case Reports
ISSN: 2582-0370
Article Type: Case Report
DOI: https://doi.org/10.36502/2024/ASJBCCR.6377
Asp Biomed Clin Case Rep. 2024 Oct 18;7(3):275-77

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Abstract
This case study presents a 53-year-old male with a history of obstructive sleep apnea, hypertension, Gastroesophageal Reflux Disease (GERD), morbid obesity, and chronic lower extremity edema who was found to be unresponsive and was diagnosed with an incidental asymptomatic portal vein aneurysm. This patient’s aneurysm was completely asymptomatic with no related findings despite this vascular anomaly usually occurring with clinical implications.

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Asploro Journal of Biomedical and Clinical Case ReportsISSN: 2582-0370Article Type: Case ReportDOI: 10.36502/2024/ASJBCCR.6377Asp Biomed Clin Case Rep. 2024 Oct 18;7(3):275-77 Abstract Full Text PDF Asymptomatic Finding of Portal Vein Aneurysm Manish Kumar1, Jashandeep Bajaj2, Muskaan Dhillon3, Kart...

18/02/2025

Latest Status of Egogram in University Students using Tokyo University Egogram (TEG)

Tomohiro Yokoyama1, Hiroshi Bando2iD*

1 Dept. of Science and Technology, , Tokushima, Japan
2 Medical Research/Tokushima University, Tokushima, Japan

Journal of Health Care and Research
ISSN: 2582-8967
Article Type: Original Article
DOI: https://doi.org/10.36502/2024/hcr.6237
J Health Care and Research. 2024 Oct 21;5(2):57-61

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Abstract
The Tokyo University Egogram (TEG) has been recognized as a valuable psychological tool for transactional analysis (TA). TEG has been revised from version 2 to version 3, and the authors have investigated its use in research involving university students. The key findings were as follows: a high prevalence of AC-dominant (dependent) types, a high occurrence of CP-low (gentle) types, dominant child (C) types were more common than parent (P) types, and few cases of A-dominant types were observed, regardless of whether students were in the science and technology departments. The occurrence rate of composite types was low, while that of single ego factors was high. First-year students tended to exhibit low CP and high AC, indicating a need for lifestyle guidance.

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Journal of Health Care and ResearchISSN: 2582-8967Article Type: Original ArticleDOI: 10.36502/2024/hcr.6237J Health Care and Research. 2024 Oct 21;5(2):57-61 Abstract Full Text PDF Latest Status of Egogram in University Students using Tokyo University Egogram (TEG) Tomohiro Yokoyama1, Hiroshi Bando2...

21/01/2025

Recent Topics for Music Therapy and Related Development

Akiyo Yoshioka1, Hiroshi Bando1,2iD*, Yu Nishikiori1

1 Shikoku Division of Integrative Medicine Japan (IMJ), Tokushima, Japan
2 Medical Research/ , Tokushima, Japan

Journal of Health Care and Research
ISSN: 2582-8967
Article Type: Commentary
DOI: https://doi.org/10.36502/2024/hcr.6236
J Health Care and Research. 2024 Sept 28;5(2):53-56

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Abstract
In the context of aging and neuropathology, recent topics in music therapy and related advancements are introduced. The authors have managed the Shikoku division of Integrative Medicine Japan (IMJ). Lifelong engagement in music activities can help maintain cognitive reserve, thus promoting brain health. Musical instrument training has been shown to improve executive function, processing speed, and verbal memory. Playing a musical instrument was associated with a significantly decreased risk of dementia, with a hazard ratio (HR) of 0.64 among the elderly. A comparison between playing an instrument and karaoke showed dementia risk HRs of 0.70 and 0.90, respectively, for elderly males. Musicians were 64% less likely to develop mild cognitive impairment (MCI) or dementia.

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Journal of Health Care and ResearchISSN: 2582-8967Article Type: CommentaryDOI: 10.36502/2024/hcr.6236J Health Care and Research. 2024 Sept 28;5(2):53-56 Abstract Full Text PDF Recent Topics for Music Therapy and Related Development Akiyo Yoshioka1, Hiroshi Bando1,2iD*, Yu Nishikiori11Shikoku Divisio...

21/01/2025

Early Detection of Pulmonary Lesion by The Reconstruction of Three-Dimensional (3D) Computed Tomography (CT)

Katsunori Ogura1, Hiroshi Bando1,2iD*, Yoshinobu Kato1, Takafumi Kawata1, Yoshikane Kato1

1 Kanaiso Hospital, Komatsushima, Tokushima, Japan
2 Medical Research/ , Tokushima, Japan

Asploro Journal of Biomedical and Clinical Case Reports
ISSN: 2582-0370
Article Type: Case Report
DOI: https://doi.org/10.36502/2024/ASJBCCR.6376
Asp Biomed Clin Case Rep. 2024 Sept 16;7(3):270-74

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Abstract
This case involves a 59-year-old female with no past medical history. She was a former smoker, consuming 5 ci******es daily from the age of 20 to 44. In late June 2024, she underwent a health check-up and was advised to have a chest CT scan. As a result, an unexpected lesion was found in the middle to upper area of the left lung, visible in the transverse aspect. The lesion had an irregular shape and measured 25.46 x 11.89 mm. Using the reconstruction method of three-dimensional (3D) computed tomography (CT) by Synapse Vincent, detailed images of the transverse, coronal, and sagittal aspects were obtained. Tumor markers were negative for CRP, CEA, and cytokeratin 19 fragment (CYFRA).

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Asploro Journal of Biomedical and Clinical Case ReportsISSN: 2582-0370Article Type: Case ReportDOI: 10.36502/2024/ASJBCCR.6376Asp Biomed Clin Case Rep. 2024 Sept 16;7(3):270-74 Abstract Full Text PDF Early Detection of Pulmonary Lesion by The Reconstruction of Three-Dimensional (3D) Computed Tomogra...

11/01/2025

Tracheal Intubation in A Patient with Breast Cancer Complicated with Maxillofacial Bone Metastasis and Bone Destruction

Ruixue Li1*

1 Department of Anesthesiology, West China Hospital, and The Research Units of West China (2018RU012), Chinese Academy of Medical Sciences, Chengdu, Sichuan Province, China

Asploro Journal of Biomedical and Clinical Case Reports
ISSN: 2582-0370
Article Type: Case Report
DOI: https://doi.org/10.36502/2024/ASJBCCR.6374
Asp Biomed Clin Case Rep. 2024 Aug 30;7(3):263-66

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Abstract
We report the tracheal intubation of a 51-year-old woman with maxillofacial bone metastasis and bone destruction following surgery for breast cancer. The patient had previously undergone radical surgery for left breast cancer and was currently experiencing complications, including bone destruction and pus discharge in the left maxillofacial region. Due to the inability to eat orally and the failure of multiple nasogastric tube placements, it was decided, after multi-department consultation, to perform a jejunostomy under general anesthesia and place a jejunal nutrition tube. Preoperative head and neck CT showed that most of the mandible was missing, there was bilateral maxillofacial and neck soft tissue swelling, and bilateral nasal stenosis. The preoperative anesthesia evaluation indicated that the patient would likely have difficulties with mask ventilation, nasal intubation, and oral laryngoscopy placement. Since conventional anesthesia methods for airway establishment through the mouth or nose were not feasible, spontaneous breathing was maintained in the awake state, and endotracheal intubation was performed under combined tracheal surface anesthesia with basic sedation and analgesia. The patient cooperated well during the intubation process. After the operation, the endotracheal tube was removed, and the patient was returned to the ward.

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Asploro Journal of Biomedical and Clinical Case ReportsISSN: 2582-0370Article Type: Case ReportDOI: 10.36502/2024/ASJBCCR.6374Asp Biomed Clin Case Rep. 2024 Aug 30;7(3):263-66 Abstract Full Text PDF Tracheal Intubation in A Patient with Breast Cancer Complicated with Maxillofacial Bone Metastasis an...

11/01/2025

The Application of Ultrasound-guided Peripheral Venipuncture in the Rescue of Hemorrhagic Shock during Operation – A Case Report

Rui Wang1*

1 Department of Anesthesiology, West China Hospital of , Sichuan Province, Chengdu , China

Asploro Journal of Biomedical and Clinical Case Reports
ISSN: 2582-0370
Article Type: Case Report
DOI: https://doi.org/10.36502/2024/ASJBCCR.6375
Asp Biomed Clin Case Rep. 2024 Aug 31;7(3):267-69

PDF:https://asploro.com/wp-content/uploads/2024/08/The-Application-of-Ultrasound-guided-Peripheral-Venipuncture-in-the-Rescue-of-Hemorrhagic-Shock-during-Operation-A-Case-Report.pdf

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Abstract
Compared to traditional peripheral venous puncture, ultrasound-guided venous puncture has a higher success rate and fewer complications. In this case, the ultrasound-guided puncture technique successfully established two peripheral venous channels for fluid rehydration, despite the surgical position limiting the field of view and scope of the scan and circulatory failure. Ultrasound-guided peripheral venous puncture can save time for patients with hemorrhagic shock and help form a more effective rescue strategy.

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Asploro Journal of Biomedical and Clinical Case ReportsISSN: 2582-0370Article Type: Case ReportDOI: 10.36502/2024/ASJBCCR.6375Asp Biomed Clin Case Rep. 2024 Aug 31;7(3):267-69 Abstract Full Text PDF The Application of Ultrasound-guided Peripheral Venipuncture in the Rescue of Hemorrhagic Shock durin...

31/12/2024

Application of Laryngeal Mask Airway in Airway Management of Patients with A Tracheal Stenosis – A Case Report

Rui Wang1*

1 Department of Anesthesiology, of , Sichuan Province, Chengdu 610041, China

Asploro Journal of Biomedical and Clinical Case Reports
ISSN: 2582-0370
Article Type: Case Report
DOI: https://doi.org/10.36502/2024/ASJBCCR.6373
Asp Biomed Clin Case Rep. 2024 Aug 29;7(3):259-62

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Abstract
Tracheal stenosis is a severe condition that significantly affects patients’ quality of life, with airway reconstruction surgery being the primary treatment. Airway management is critical during general anesthesia, especially when the airway is the surgical site. This report presents clinical concepts and cases of the successful use of laryngeal masks as a supraglottic airway for intraoperative tracheal management in patients with tracheal stenosis. As a transitional device for airway management, a laryngeal mask can provide adequate ventilation and oxygenation and should be incorporated into airway control protocols for individuals with tracheal stenosis.

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Asploro Journal of Biomedical and Clinical Case ReportsISSN: 2582-0370Article Type: Case ReportDOI: 10.36502/2024/ASJBCCR.6373Asp Biomed Clin Case Rep. 2024 Aug 29;7(3):259-62 Abstract Full Text PDF Application of Laryngeal Mask Airway in Airway Management of Patients with A Tracheal Stenosis - A Ca...

31/12/2024

Anesthetic Management of Pediatric Ingestion of Multiple Magnetic Beads: A Case Report

Jie Zhong1*

1 Department of Anesthesiology, West China Hospital, West China School of Medicine, , Chengdu, China

Asploro Journal of Biomedical and Clinical Case Reports
ISSN: 2582-0370
Article Type: Case Report
DOI: https://doi.org/10.36502/2024/ASJBCCR.6369
Asp Biomed Clin Case Rep. 2024 Aug 30;7(3):241-44

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Abstract
The incidence of magnet ingestion among children is increasing, though it remains rare. This case describes a 3-year-old child who ingested multiple magnetic beads and was planned to have the foreign bodies removed by endoscopy under sedation. However, perioperative hypoxemia occurred because gastric perforation had not been detected beforehand. An exploratory laparotomy was performed immediately, all magnetic beads were extracted, and the stomach perforation was closed. This report emphasizes the importance of anesthesia evaluation, anesthesia preparation, airway management, and intraoperative circulation maintenance.
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Asploro Journal of Biomedical and Clinical Case ReportsISSN: 2582-0370Article Type: Case ReportDOI: 10.36502/2024/ASJBCCR.6369Asp Biomed Clin Case Rep. 2024 Aug 30;7(3):241-44 Abstract Full Text PDF Anesthetic Management of Pediatric Ingestion of Multiple Magnetic Beads: A Case Report Jie Zhong1*1De...

31/12/2024

Residual Leiomyosarcoma in the Inferior Vena Cava after Thrombectomy under Cardiopulmonary Bypass: The Role of Intraoperative Ultrasonography

Jiaxin He1iD*

1 Department of Anesthesiology, West China Hospital, West China School of Medicine, , Chengdu, China

Asploro Journal of Biomedical and Clinical Case Reports
ISSN: 2582-0370
Article Type: Case Image
DOI: https://doi.org/10.36502/2024/ASJBCCR.6370
Asp Biomed Clin Case Rep. 2024 Aug 26;7(3):245-46

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Abstract
A 52-year-old woman with chronic low back pain was found to have a leiomyosarcoma causing a tumor thrombus obstructing the IVC, visible on transesophageal echocardiography. After surgery, which included tumor and thrombus removal, a residual thrombus was seen on imaging. Anticoagulation was started postoperatively, and the patient had a successful recovery.
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Asploro Journal of Biomedical and Clinical Case ReportsISSN: 2582-0370Article Type: Case ImageDOI: 10.36502/2024/ASJBCCR.6370Asp Biomed Clin Case Rep. 2024 Aug 26;7(3):245-46 Abstract Full Text PDF Residual Leiomyosarcoma in the Inferior Vena Cava after Thrombectomy under Cardiopulmonary Bypass: The...

06/12/2024

Risk Factors for Postoperative Delirium in Thoracic Surgery Patients – A Prospective Cross-sectional Study

Rui Wang1*

1 Department of Anesthesiology, West China Hospital of Sichuan University, Sichuan Province, Chengdu 610041, China

Asploro Journal of Biomedical and Clinical Case Reports
ISSN: 2582-0370
Article Type: Original Article
DOI: https://doi.org/10.36502/2024/ASJBCCR.6372
Asp Biomed Clin Case Rep. 2024 Aug 26;7(3):250-58

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Abstract
Background: Postoperative delirium (POD) is a common complication that affects the prognosis and outcome. The risk factors of different surgical types have significance in preventing POD. Still, there are few studies on the risk factors for this complication of thoracic surgery, and further research and exploration are necessary.
Method: This study intends to conduct a prospective cross-sectional study, including patients undergoing elective thoracic surgery. The primary outcome is the incidence of POD 1-7 days after surgery or before discharge. The essential information on patients, surgery, anesthesia, and postoperative details are gathered for statistical analysis. We are exploring the potential relationship between anesthesia-related factors and POD.
Result: One hundred seventy-five patients were included in this study, and 17 (9.7%) patients developed POD. Univariate analysis showed that age-adjusted Charlson Comorbidity Index (aCCI), educational attainment, blood transfusion, artificial blood vessel replacement, and indwelling urinary catheter were statistically different. Logistic regression results showed that the aCCI index (OR 1.811, 95% CI 1.058-3.103; P=0.030), the ambulation time (OR 12.303, 95% CI 2.670-56.686; P=0.001) increased POD risk. In patients undergoing thoracotomy, blood transfusion (RR 16.875, 95% CI 2.149-132.508; P=0.012) was statistically different between POD and non-POD groups.
Conclusion: The results of this study showed that the higher the aCCI index, the later the ambulation time is the risk factor for POD in thoracic surgery patients. The risk of POD may be heightened in thoracic surgery patients who require a blood transfusion. However, additional research is warranted to confirm these findings.

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Asploro Journal of Biomedical and Clinical Case ReportsISSN: 2582-0370Article Type: Original ArticleDOI: 10.36502/2024/ASJBCCR.6372Asp Biomed Clin Case Rep. 2024 Aug 26;7(3):250-58 Abstract Full Text PDF Risk Factors for Postoperative Delirium in Thoracic Surgery Patients - A Prospective Cross-secti...

06/12/2024

Vasovagal Reflex Shock Following Femoral Artery Cannulation in a Patient with Chronic Heart Failure: A Case Report

Xuewei Liu1iD*

1 Department of Anesthesiology, West China Hospital, West China School of Medicine, , Chengdu, China

Asploro Journal of Biomedical and Clinical Case Reports
ISSN: 2582-0370
Article Type: Case Report
DOI: https://doi.org/10.36502/2024/ASJBCCR.6371
Asp Biomed Clin Case Rep. 2024 Aug 22;7(3):247-49

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Abstract
Coronary artery disease is a major type of heart disease, and coronary angiography has been widely utilized as a diagnostic method. Percutaneous coronary intervention (PCI) has become an important approach for restoring coronary perfusion. The vasovagal reflex is a common and potentially life-threatening acute complication associated with coronary interventions, which can lead to cardiac arrest in severe cases. This case report describes a patient with coronary heart disease who experienced vasovagal reflex-induced shock during the post-anesthesia care unit (PACU) period following the procedure.

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Asploro Journal of Biomedical and Clinical Case ReportsISSN: 2582-0370Article Type: Case ReportDOI: 10.36502/2024/ASJBCCR.6371Asp Biomed Clin Case Rep. 2024 Aug 22;7(3):247-49 Abstract Full Text PDF Vasovagal Reflex Shock Following Femoral Artery Cannulation in a Patient with Chronic Heart Failure:....

30/11/2024

Adolescent Idiopathic Scoliosis Treated with Simultaneous Translation on Two Rods (ST2R) Involving Preoperative, Postoperative, and Follow-Up Evaluation by EOS 3D Imaging: A Case Series

Rodrigo Góes Medéa de Mendonça1iD*, Giuliana Haddad Taralli de Mendonça1iD, Jeffrey R. Sawyer1iD, Derek M. Kelly1iD

1 University of Tennessee-Campbell Clinic Department of Orthopaedic Surgery & Biomedical Engineering, Le Bonheur Children’s Hospital, Memphis TN, USA

Asploro Journal of Biomedical and Clinical Case Reports
ISSN: 2582-0370
Article Type: Case Series
DOI: https://doi.org/10.36502/2024/ASJBCCR.6368
Asp Biomed Clin Case Rep. 2024 Aug 22;7(3):233-40

PDF:https://asploro.com/wp-content/uploads/2024/08/Adolescent-Idiopathic-Scoliosis-Treated-with-Simultaneous-Translation-on-Two-Rods-ST2R-Involving-Preoperative-Postoperative.pdf

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Abstract
Objective: To evaluate preoperative, postoperative, and follow-up of spinal and pelvic parameters using EOS 3D imaging in adolescent idiopathic scoliosis (AIS) patients who underwent simultaneous translation on two rods (ST2R) technique for corrective posterior spinal surgery.
Methods: Five patients had surgical correction of Lenke type 1 or 2 AIS using the ST2R technique. The preoperative average Cobb angle was 72.4° ± 19.4. Low-dose standing biplanar radiographs were obtained to evaluate several spinal and pelvic parameters preoperatively (five patients), immediately postoperatively (four patients), and at follow-up (four patients). Three-dimensional reconstructions were performed (a total of 13 reconstructions).
Results: The mean number of levels fused was 11.2° ± 2.0. The number of pedicle screws used for constructs averaged 19.2° ± 3.06 (1.75 density screw per vertebra). The Cobb angle values were significantly changed by the operation (75° ± 21 to 28° ± 7, p = 0.009), but no other parameters were altered. The maximal apical axial change at the junctional region was 32.8° (absolute value), and the minimal apical axial change at the apical region was 4.8° (absolute value). The intervertebral rotation difference in the axial plane was larger near the apical region (T8-T9), from 2.1° ± 2.7 to -14° ± 6.9, and smaller near the junctional region (T12-L1), from -2.6° ± 2.9 to -1.1° ± 8.4.
Conclusion: This case series suggests that corrective posterior spinal surgery for AIS using ST2R can achieve both 3D correction of the spine and additional intervertebral axial rotation, with minimal deterioration during follow-up. Preoperative, postoperative, and follow-up evaluation can be accurately evaluated with EOS low-dose 3D imaging.

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Asploro Journal of Biomedical and Clinical Case ReportsISSN: 2582-0370Article Type: Case SeriesDOI: 10.36502/2024/ASJBCCR.6368Asp Biomed Clin Case Rep. 2024 Aug 22;7(3):233-40 Abstract Full Text PDF Adolescent Idiopathic Scoliosis Treated with Simultaneous Translation on Two Rods (ST2R) Involving Pr...

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