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Risk of Heart Failure Increased More Than 40% in Primary Sjögren’s
16/12/2022

Risk of Heart Failure Increased More Than 40% in Primary Sjögren’s

Primary Sjögren’s syndrome patients have a higher risk of heart failure, cardiovascular problems compared to healthy people, a study shows.

Vagus Nerve Stimulation May Ease Fatigue in Sjögren’s Patients
06/12/2022

Vagus Nerve Stimulation May Ease Fatigue in Sjögren’s Patients

Sjögren’s syndrome patients using a device to stimulate the vagus nerve in the neck twice daily reported lesser mental and physical fatigue.

Sjögren’s and Rare Skin Disorder Found in Chinese Woman, 69
29/11/2022

Sjögren’s and Rare Skin Disorder Found in Chinese Woman, 69

A new case study reports on a 69-year-old woman in China diagnosed with two rare autoimmune diseases, one of them Sjögren’s syndrome.

Miscarriage Risk Nearly 9 Times Higher in Women With Sjögren′s: Study
22/11/2022

Miscarriage Risk Nearly 9 Times Higher in Women With Sjögren′s: Study

Sjögren's syndrome is linked to a significantly increased risk of miscarriage and other adverse pregnancy problems, a meta-analysis finds.

Low Dose IL-2 Improves Salivary Gland Function in Sjögren’s Mouse Model
15/11/2022

Low Dose IL-2 Improves Salivary Gland Function in Sjögren’s Mouse Model

Treatment with a low dose of interleukin-2, an immune signaling protein, improved salivary gland function in a Sjögren’s syndrome mouse model

Motto Launches App to Help Manage Sjögren’s, Other Autoimmune Diseases
08/11/2022

Motto Launches App to Help Manage Sjögren’s, Other Autoimmune Diseases

With its new app, Motto Health has launched a type of virtual clinic to aid patients with autoimmune diseases like Sjögren’s syndrome.

Herpes Zoster Infection Increases Risk of Sjögren’s Syndrome, Study Reports
25/10/2022

Herpes Zoster Infection Increases Risk of Sjögren’s Syndrome, Study Reports

People with a history of herpes zoster, mainly those with no other conditions, are at an increased risk of developing Sjögren’s syndrome.

Biomarkers of Interstitial Lung Disease in Sjögren’s Syndrome Identified in Study
18/10/2022

Biomarkers of Interstitial Lung Disease in Sjögren’s Syndrome Identified in Study

Age, disease duration, and blood levels of inflammatory markers can distinguish Sjögren’s syndrome patients with interstitial lung disease.

B-cell Sugar Metabolism Overly Active in Sjögren’s; May Be Treatment Target
11/10/2022

B-cell Sugar Metabolism Overly Active in Sjögren’s; May Be Treatment Target

Research that targets the glucose pathway glycolysis might be a potential therapeutic strategy for Sjögren’s syndrome, a study suggests.

Sjögren’s Patients More Likely to Need Hospital Care Due to Infections
05/10/2022

Sjögren’s Patients More Likely to Need Hospital Care Due to Infections

A study shows Sjögren’s patients are more likely than healthy people to need inpatient hospital care for infections acquired in the community.

Cytotoxic Immune Cells in Lips Key to Tissue Damage in Sjögren’s
27/09/2022

Cytotoxic Immune Cells in Lips Key to Tissue Damage in Sjögren’s

In patients with severe Sjögren’s, cytotoxic immune cells were found to build up in the salivary glands of the lips, causing tissue damage.

ETS1 Protein Powers Up MMP-9 in Salivary Glands in Sjögren’s, Sicca Patients
20/09/2022

ETS1 Protein Powers Up MMP-9 in Salivary Glands in Sjögren’s, Sicca Patients

In Sjögren’s patients, large amounts of the ETS1 protein are found in the salivary glands, where it may be key in making more MMP-9 protein.

Dazodalibep Eases Moderate-to-high Disease Activity in Sjögren’s Patients: Trial Data
13/09/2022

Dazodalibep Eases Moderate-to-high Disease Activity in Sjögren’s Patients: Trial Data

Dazodalibep markedly eased disease activity in Sjögren's syndrome patients who live with moderate-to-high systemic disease activity.

Changes to Corneal Nerves Found in Adults With Sjögren’s in Imaging Study
06/09/2022

Changes to Corneal Nerves Found in Adults With Sjögren’s in Imaging Study

A rapid, non-invasive imaging technique called IVCM was shown to detect corneal nerve changes in the eyes of adults with Sjögren's syndrome.

Malaria Treatment Shows Potential in Animal, Cell Models of Sjögren’s
30/08/2022

Malaria Treatment Shows Potential in Animal, Cell Models of Sjögren’s

Research in Sjögren’s syndrome found artesunate, approved for malaria, eased symptoms in a mouse model by inhibiting inflammatory Th17 cells.

Memory Problems Common in Sjögren’s, Linked to Global Cognitive Impairment
24/08/2022

Memory Problems Common in Sjögren’s, Linked to Global Cognitive Impairment

Memory problems are common in primary Sjögren’s syndrome patients and are linked to global cognitive impairment, according to a small study.

10 New Genetic Regions Linked to Increased Risk of Sjögren’s in Study
16/08/2022

10 New Genetic Regions Linked to Increased Risk of Sjögren’s in Study

A study found 10 new genetic regions (loci) that are linked to the risk of Sjögren’s syndrome in people with ancestry in Europe.

Salivary Gland Ultrasound May Improve Sjögren’s Patient Stratification, Trial Design
09/08/2022

Salivary Gland Ultrasound May Improve Sjögren’s Patient Stratification, Trial Design

An ultrasound evaluation of salivary gland damage may aid stratification of primary Sjögren’s syndrome patients, a study suggests.

Elevated Uric Acid Blood Levels May Lead to High Blood Pressure With Sjögren’s
02/08/2022

Elevated Uric Acid Blood Levels May Lead to High Blood Pressure With Sjögren’s

Higher blood levels of uric acid independently linked with high blood pressure, risking cardiovascular disease, in primary Sjögren’s patients.

Scleroderma-related Autoantibodies Common in Sjögren’s Cases: Study
26/07/2022

Scleroderma-related Autoantibodies Common in Sjögren’s Cases: Study

Self-targeting antibodies typically associated with scleroderma may be useful in a diagnostic workup of people with Sjögren's syndrome.

World Sjögren’s Day – Putting a Face on the Disease – Set for July 23
19/07/2022

World Sjögren’s Day – Putting a Face on the Disease – Set for July 23

Supporters globally are poised to mark World Sjögren’s Day, set aside each July 23rd to raise awareness of the chronic autoimmune disorder.

World Sjögren’s Day – Putting a Face on the Disease – Set for July 23rd
19/07/2022

World Sjögren’s Day – Putting a Face on the Disease – Set for July 23rd

Supporters globally are poised to mark World Sjögren’s Day, set aside each July 23rd to raise awareness of the chronic autoimmune disorder.

Immune Cell Alterations in Eyes Linked to Sjögren’s Severity Bodywide
12/07/2022

Immune Cell Alterations in Eyes Linked to Sjögren’s Severity Bodywide

Alterations to immune dendritic cells in the eye of Sjögren’s patients were associated both with bodywide and eye-related disease severity.

Inflammatory Molecule IL-7 Linked to Sjögren’s Disease Activity, Inflammation
11/07/2022

Inflammatory Molecule IL-7 Linked to Sjögren’s Disease Activity, Inflammation

Levels of the molecule IL-7 are increased in Sjögren's patients, suggesting it may be a potential biomarker for monitoring disease activity.

Quick and Non-invasive Imaging Tool May Help to Diagnose Sjögren’s, Study Reports
09/07/2022

Quick and Non-invasive Imaging Tool May Help to Diagnose Sjögren’s, Study Reports

Read about a study suggesting sonoelastography, an imaging tool using ultrasound, can help diagnose Sjögren's by marking tissue rigidity in salivary glands.

Industry leaders seek to advance innovative resources for rare and orphan disease communities amid COVID-19 outbreak
08/07/2022

Industry leaders seek to advance innovative resources for rare and orphan disease communities amid COVID-19 outbreak

Read about a new announcement between FFF Enterprises and BioNews Services to bring next-generation solutions to the rare and chronic disease clinical trial process.

Inflammatory Molecule IL-7 Linked To Sjögren’s Disease Activity, Inflammation
05/07/2022

Inflammatory Molecule IL-7 Linked To Sjögren’s Disease Activity, Inflammation

Levels of the molecule IL-7 are increased in Sjögren's patients, suggesting it may be a potential biomarker for monitoring disease activity.

MRI, Ultrasound May Help in Early Diagnosis of Juvenile Sjögren’s
28/06/2022

MRI, Ultrasound May Help in Early Diagnosis of Juvenile Sjögren’s

MRI and ultrasounds can detect changes in salivary glands suggestive of primary juvenile Sjögren’s syndrome before dryness symptoms begin.

27/06/2022

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