Aurea Care Medical Science Journal

18/10/2023

In the relentless quest for effective COVID-19 management strategies, the role of cannabinoids emerges as a captivating frontier. Our latest article, "The Role of Cannabinoids in SARS-CoV-2 Infection and COVID-19 Management," meticulously explores the antiviral, immunomodulatory, and potentially neuroprotective properties of cannabinoids against the backdrop of SARS-CoV-2 infection.

From inhibiting key viral enzymes to modulating the often deleterious immune responses, the article navigates through the complex molecular mechanisms underlying the interaction between cannabinoids and the virus. It further underscores the critical need for robust clinical trials to translate these early insights into viable therapeutic interventions.

With a panoramic view of current research landscapes and a clarion call for further rigorous investigations, this article seeks to foster informed discussions among healthcare providers, researchers, and the broader scientific community.
Delve into the intricate interplay of cannabinoids and COVID-19, and join the discourse on advancing our therapeutic armamentarium against this global health menace.

Explore the intersection of cannabinoids and COVID-19 management, shedding light on the antiviral, immunomodulatory, and neuroprotective potentials of cannabinoids against SARS-CoV-2. Delve into the clinical implications, risks, and future prospects as we navigate through existing research towards a...

16/10/2023

📢 Exciting New Research Alert: Transforming Cannabis Perceptions in Sinaloa, Mexico 🌿🔬

👉 Are evidence-based educational interventions effective in changing public attitudes towards cannabis, especially in regions with historically repressive drug policies?

Our latest article breaks down a recent study published in Nature Scientific Reports. The research reveals how targeted scientific information significantly shifted public opinion. The findings are a testament to the power of fact-based education in dispelling myths and reducing stigma around cannabis use.

👀 Key Takeaways:
Dramatic shifts in attitudes across diverse demographics
Implications for evidence-based policy decisions
The nuanced role of age and educational background in shaping perceptions

📌 Whether you're a policy maker, healthcare professional, or simply interested in the ever-evolving landscape of cannabis regulations and public opinion, this article offers critical insights.

Unveil the transformative impact of evidence-based education on public attitudes towards cannabis in Sinaloa, Mexico. Explore how demographic factors mediate the effectiveness of educational interventions and what this means for future drug policies. A must-read for anyone interested in the intersec...

11/10/2023

🔬 New Article Alert: Unveiling the Bidirectional Relationship Between the Endocannabinoid System and PPARγ

I'm thrilled to announce the publication of our latest article that dives deep into the fascinating relationship between the Endocannabinoid System (ECS) and Peroxisome Proliferator-Activated Receptor Gamma (PPARγ).

👉 Key Highlights
🌐 Comprehensive overview of the ECS and PPARγ
🧪 Molecular interactions and signal transduction pathways
🚀 Emerging therapeutic implications

🔍 Why Should You Read It?
Gain cutting-edge insights into metabolic and inflammatory regulation.
Discover the molecular intricacies that govern this bidirectional relationship.
Understand the vast therapeutic potential that could revolutionize treatments for metabolic disorders, inflammation, and beyond.

🎯 Who Should Read It?
Healthcare Professionals
Molecular Pharmacologists
Researchers
Students in Biomedical Sciences

👇 Check out the article now!
Don't forget to share it with your network if you find it valuable. Your feedback is always appreciated!

Dive deep into the symbiotic relationship between the Endocannabinoid System and PPARγ. Understand their roles in metabolism, inflammation, and potential as therapeutic targets. A must-read for healthcare professionals, pharmacologists, and researchers interested in metabolic and inflammatory disor...

09/10/2023

🔬 Excited to share our latest review article exploring the captivating interplay between dietary and the . This comprehensive review delves into the molecular dialogues governing this interaction, unveiling a promising frontier for disease prevention and management.

🍽️ Bridging and , the article underscores the potential of dietary omega fatty acids in modulating physiological processes. Through a detailed analysis, it highlights the implications for healthcare professionals, medical education, and policy.

🤝 Encouraging interdisciplinary collaboration, this narrative advocates for a holistic, nutrition-informed approach to healthcare. The findings spotlight the critical role of balanced omega fatty acid intake in maintaining health and preventing disease.

🔗 I invite you to delve into this narrative that melds molecular insights with nutritional science, fostering a deeper understanding of the therapeutic potential harbored within dietary modulation of the .

Uncover the molecular dialogues between dietary omega fatty acids and the Homeostatic System. This comprehensive review highlights the pivotal role of omega fatty acids in modulating physiological processes, offering insights into potential therapeutic interventions and the importance of interdiscip...

29/09/2023

📣 New Article Alert: "The Homeostatic System: Effects on auxiliary physiological systems"

🔬 Are you intrigued by the deep interconnections within human physiology? Do you believe in a holistic approach to medicine? If so, our latest article is a must-read!

✍️ Authors:
Stefan Broselid, Ph.D., Editor-in-chief
Sasha Weedowitch, BN, Clinical Endocannabinologist

👨‍⚕️ Target Audience: Healthcare Providers, Medical Educators, Researchers, and Students

📝 Key Takeaways:
Comprehensive overview of the ECS's interactions with multiple physiological systems
Advanced insights into ECS's role in modulating activities like pain, neuroplasticity, and hormonal balance
A strong argument for renaming the ECS to the 'Homeostatic System'

💡 Why You Should Read This Article:
The Endocannabinoid System (ECS) plays a vital role in maintaining the body's internal equilibrium. Understanding its mechanisms can revolutionize pharmacology, personalized medicine, and healthcare in general. This article is a deep dive into the ECS, exploring its roles and advocating for its inclusion in medical curricula and clinical practice.

👏 A special shout-out to my co-author, Sasha Weedowitch, BN, whose contributions and discussions have been invaluable in making this article a comprehensive and authoritative resource.

Don't miss out on this enlightening read. Share it with your network and join the conversation to elevate healthcare and medical education!

Dive into the intricate roles of the Endocannabinoid System (ECS) in regulating physiological homeostasis across diverse organ systems. Co-authored by two experts in the field, Stefan Broselid, Ph.D. and Sasha Weedowitch, BN, this article serves as an essential guide for healthcare providers, resear...

26/09/2023

We are thrilled to announce the publication of an exclusive interview with Dr. Amal Hagos.

👉 "Navigating the Complex Landscape of Medical Cannabis: A Conversation with Dr. Amal Hagos on Ethics, Evidence, and Patient Care"

In this illuminating discussion, Dr. Hagos delves into:
1️⃣ Ethical Implications in Cannabinoid Medicine
2️⃣ The Importance of Evidence-Based Practices
3️⃣ Advancements in Patient-Centric Approaches

🧬 Imagine the double helix of DNA, where one strand represents ethical considerations and the other signifies scientific rigor. Just like how the strands twist together to create the blueprint of life, ethics and science in medical cannabis are intertwined in an equally intricate manner.

🎯 Why You Should Read This:
Gain insights into the challenges and opportunities in cannabinoid medicine
Understand the intersection of ethics and evidence in patient care
Receive practical advice on implementing best practices in your clinical setting
Learn about medical cannabis in Swedish healthcare

An enlightening discussion with Dr. Amal Hagos, a pain management specialist at Aurea Care in Stockholm, on the complexities and future of medical cannabis in treating chronic pain. This interview dives into evidence-based practices, the endocannabinoid system, ethical considerations, and much more.

19/09/2023

📣 New Publication Alert: Unveiling New Horizons in Autism Research
We are thrilled to announce the publication of a groundbreaking article in our latest issue: "Exploring Autistic Spectrum Disorder through the lens of ECS dysfunction."

🧩 Why This is Important
Autism Spectrum Disorders (ASD) are a complex set of neurodevelopmental conditions affecting millions worldwide. While research has made strides in understanding ASD, much remains to be discovered. This article delves deep into the involvement of the Endocannabinoid System (ECS) in ASD, shedding light on potential therapeutic avenues.

🔬 What You'll Learn
The role of the ECS in neuropsychiatric conditions, including ASD
Insights from in-vivo models that show ECS dysfunction in ASD
Human biomarker studies that corroborate ECS involvement in ASD
A comprehensive review of clinical trials focusing on ECS modulation for ASD treatment

🎯 Who Should Read This
Healthcare Professionals
Researchers in Neuroscience and Pharmacology
Medical Educators
Policy Makers in Healthcare

📚 Read and Share
Tap into this reservoir of knowledge that bridges the gap between complex scientific research and clinical application. Perfect for healthcare providers looking for a more nuanced understanding of ASD and its potential treatment pathways.

Dive into an extensive review highlighting the intricate relationship between the Endocannabinoid System (ECS) and Autism Spectrum Disorders (ASD). Uncover key insights from in vivo models, clinical trials, and biomarker studies, shedding light on ECS dysfunction in ASD. This article aims to pave th...

11/09/2023

🌿 Breaking Research Update in the Realm of Neuropathic Pain 🌿

We are thrilled to share an insightful article that dives into a seminal study published in the Journal of Pain Research. The paper, "The Endocannabinoid Analgesic Entourage Effect: Investigations in Cultured DRG Neurons," by Anand et al., unveils groundbreaking findings about the analgesic potential of three endocannabinoids — 2-AG, 2-PG, and 2-LG.

🔍 Key Takeaways:
The study pivots from the well-studied area of phytocannabinoids to the body's own lipid-based signaling molecules: endocannabinoids.
Employing a cultured rat dorsal root ganglion (DRG) neuron model, the research unravels the efficacy of individual and combined applications of these endocannabinoids in delaying capsaicin-induced TRPV1 activation. 🐀
Remarkably, the combined treatment affected a broader subset of neurons, inhibiting capsaicin-triggered responses in up to 96% of the neurons examined. Importantly, the effects are seen at nanomolar concentrations rather than at much higher micromolar concentrations, which is when phytocannabinoids act on TRPV1 receptors.

🌡 Why This Matters:
Chronic pain is a pervasive and often debilitating condition that affects approximately 1 in 15 individuals globally. This study not only enriches our molecular understanding of pain signaling but also opens new doors for the development of next-generation analgesics. 💊

Unpacking the study "The Endocannabinoid Analgesic Entourage Effect," this article delves into the analgesic potential of endocannabinoids 2-AG, 2-PG, and 2-LG. Learn how these lipid-based signaling molecules influence TRPV1 receptor activation and offer new prospects for chronic pain management.

08/09/2023

04/09/2023

📊 I'm excited to share this one-pager that provides a comparative analysis of cannabis-based treatment outcomes, using Certainty Levels, Odds Ratios (ORs), and 95% Confidence Intervals (CIs). The visual aid uses the data from the recent article that aims to balance the discourse around cannabis use.

👇 Key Highlights of the One-Pager:
1️⃣ Categorized effects of cannabis into Positive, Negative, and Special Populations.
2️⃣ Integrated GRADE Certainty Levels to evaluate the quality of evidence.
3️⃣ Included the number and types of contributing studies for robustness.
4️⃣ Annotated specific outcomes and statistical parameters for nuanced understanding.
Read the full breakdown here: https://aureamedicalsciencejournal.se/bmj-umbrella-review/

04/09/2023

📣 New Publication Alert: A Breakdown of Solmi et al.’s BMJ Umbrella Review regarding harms and benefits of cannabis use

🌿 This umbrella review is the first of its kind to combine observational and interventional studies on the effects of cannabinoids on humans.

📈 The paper features a meticulously designed one-pager, summarizing the outcomes based on GRADE Certainty Levels, Odds Ratios (ORs), and 95% Confidence Intervals (CIs). This visual summary serves as a quick reference for busy professionals.

🔑 Key Takeaways:
1️⃣ Balanced discussion on the risks and benefits of cannabis use.
2️⃣ GRADE framework employed to evaluate the quality of evidence.
3️⃣ Comparative analysis with alcohol, revealing striking disparities in Disability-Adjusted Life Years.
4️⃣ Potential implications for clinical guidelines and public policy.

🎯 Who Should Read This?
Clinicians
Other Healthcare Professionals
Public Health Researchers
Policymakers

🌟 Don't miss out on this ground-breaking study that could reshape how we perceive and regulate cannabis. Dive into the full article for a comprehensive understanding that only a rigorously designed umbrella review can offer.

✅ Like, share, and comment to keep this essential conversation going!

Dive into a groundbreaking umbrella review comparing the risks and benefits of cannabis and alcohol. Utilizing the GRADE framework, this article provides a multi-faceted analysis that could reshape both clinical guidelines and public policy. Includes a detailed chart visualizing GRADE certainty leve...

01/09/2023

🔬 New Article Alert: Decoding the Symphony - Genetic Variations in the ECS and Their Impact on Health 🧬

I'm thrilled to share our latest article that dives deep into the complex yet fascinating landscape of the Endocannabinoid System (ECS), or what we prefer to refer to as the Master Homeostatic Regulatory System (MHRS), and the role that genetic alterations of its components have on behavior and disease.
🎯 Why Is This Important?
The ECS functions as a biological 'maestro,' orchestrating a multitude of physiological processes from mood regulation to immune functionality. Understanding its genetic nuances is critical for unlocking new avenues in personalized medicine and therapeutic interventions.

📝 What Does the Article Cover?
A comprehensive overview of the ECS and its principal components.
The impact of genetic polymorphisms on behavior and disease susceptibility.
A comprehensive table of known genetic alterations in ECS components and their known effects on the role of ECS, health and disease.

🌐 Key Takeaways
Gain a holistic perspective on the intricacies of human physiology.
Understand the therapeutic potential and limitations presented by ECS genetic mutations.
Contemplate the ethical dimensions and future directions of this burgeoning field.

Don't miss out on this opportunity to deepen your scholarly engagement with the ECS. It's not just an academic exercise; it's a pathway to more targeted, effective healthcare solutions.

As always, feel free to share your thoughts and insights in the comments field below!

"Decoding the Symphony: Genetic Variations in the ECS and Their Impact on Health" offers an in-depth analysis of the Endocannabinoid System's role in human physiology and its vulnerability to genetic mutations. The article provides an insightful look into how these genetic variations can influence b...

28/08/2023

🌳 officinalis, a staple botanical plant in ancient Eastern medicine for over 2,500 years, is making waves in the scientific community. Recent research by Borgonetti et al., published in the journal Antioxidants, has illuminated its potential in neuropathic pain management by acting on the and the .

As more and more research becomes available, it is getting evidently clear that the cannabis plant is by far from unique in producing cannabinoid receptor-interacting molecules with potential therapeutic properties.

24/08/2023

🎗️ Unveiling the Power of a Trio of Phytocannabinoids in the Fight Against Cancer!

🌿 In an era where innovative solutions are shaping the future of healthcare, a groundbreaking study from renowned Israeli researcher Dedi Meiri's research group is taking a significant step forward.

🔬 This breakdown of the brand-new pre-print at BioRxIv investigates the synergistic effects of cannabinoids 331-18A, CBDV, and CBD. The research not only targets a specific form of leukemia but also manages to unravel convincing 'entourage effects' using this unique combination of phytocannabinoids.

🧪 The study's comprehensive analysis, including in vitro and in vivo experiments, reveals exciting new avenues for targeted cancer therapy. It opens up possibilities for the development of novel treatments and paves the way for more extensive research in molecular pharmacology.

🎓 As a beacon in the ever-evolving field of phytocannabinoid research and the Master Homeostatic Regulatory System (MHRS), this study is a must-read for professionals, academics, and enthusiasts alike.

Discover the pioneering work led by David “Dedi” Meiri that unveils the synergistic potential of three specific cannabinoids (331-18A, CBDV, and CBD) in battling NOTCH1-Mutated T-ALL. This comprehensive study, currently in preprint in BioRxIv, explores both in vitro and in vivo experiments to de...

22/08/2023

🧠 New Insights into THC's Neurological Effects Unveiled! 🧠

Excited to publish this breakdown of a recent groundbreaking fMRI study by Pelgrim et al. This impressive study unravels the intricate relationship between THC, the brain's communication networks, and genetic modulation.

🔬 Key Highlights:
- Exploration of THC's impact on the Salience Network & Hippocampus-Midbrain-Striatum Network.

- Uncovering genotype-dependent reactions to THC, specifically with the COMT gene.

- Implications for understanding mental health conditions like depression and schizophrenia.

Whether you're in the field of pharmacology, neurology, or simply interested in the scientific aspects of cannabis, this article offers a rich understanding of how THC interacts with our brain and genetic makeup.

Join the conversation and let's explore how these findings can shape future research, medical applications, and our overall understanding of the endocannabinoid system - or Master Homeostatic Regulatory System (MHRS).

"Dissecting the Acute Neurological Effects of THC" provides a comprehensive analysis of THC's acute effects on the brain. Drawing from resting state fMRI and genetic modulation, the study reveals how THC alters the brain's functionality, especially in individuals with specific genetic makeups. The f...

16/08/2023

We've just dived deep into the recent groundbreaking study by Syed et al. from 2023, which sheds light on the global perspectives of physicians on medical cannabis. The findings? An undeniable need for improved education, guidelines, and understanding.

🌎 Representing physicians from 17 countries, this study uncovers significant global knowledge gaps and varied attitudes, emphasizing the importance of education and staying informed in this rapidly evolving field.

📖 Read our comprehensive scientific summary and discover where the medical community stands on this controversial yet crucial topic.

Unpacking Syed et al.'s groundbreaking 2023 study on physicians' perspectives of medical cannabis. Explore international insights, knowledge gaps, and the call for a more informed medical community on the use and potential of cannabis in treatment.

24/07/2023

🌱 Thrilled to share an insightful interview with Sasha Weedowitch, a Mental Health Nurse and Clinical Endocannabinologist hailing from Bosnia-Hercegovina. Sasha is renowned for his holistic approach to mental health treatment, employing endocannabinology-based strategies.

💡 In the interview, Sasha sheds light on the field of endocannabinology, a discipline that emphasizes the balance of the Endocannabinoid System (ECS) in maintaining our mental and physical health. He provides a clear distinction between an 'endocannabinology approach' and a 'medical cannabis approach', stating his methods focus on overall lifestyle changes with cannabis being considered a last resort option.

🎙️ Sasha will be gracing the stage at the Stockholm Medical Cannabis Conference 2023, where he'll expound on his innovative therapeutic techniques, honed by years of mental health nursing experience.

🧠 Among many other key points, Sasha explains how the ECS is integral to both general and mental health. He recommends starting with lifestyle interventions like nutrition, stress management, and fostering strong interpersonal relationships when adopting an endocannabinology approach.

💼 He also explores his plans to launch a program for Homeostatica Mental Health Coaches to tackle Europe's growing mental health crisis, and discusses the promising role of non-THC cannabinoids like CBD and BCP in therapeutic strategies.

✨ Let's applaud Sasha's remarkable commitment to patient-centred care and his trailblazing efforts in harnessing the power of endocannabinology in mental health nursing.

Check out the full interview for more insights and get ready to delve deep into the fascinating world of endocannabinology!

Discover the field of endocannabinology and its focus on the endocannabinoid system (ECS) for maintaining mental and physical health. Learn how the 'endocannabinology approach' differs from a 'medical cannabis approach'. Gain insights into integrating endocannabinology into mental health nursing. Re...

10/07/2023

🌐 We are pleased to share this story about the upcoming Stockholm Medical Cannabis Conference 2023 and proud to be involved in its arrangement.

🔬 This conference is set to unfold amidst Sweden's stringent drug policies and rising societal unrest. The goal? To shed light on the potential benefits of medical cannabis through evidence-based education and open dialogue, free from the shadow of stigma.

🎗 The event will not only provide valuable knowledge about cannabinoid medicine but will also give a platform to patients who have benefitted from medical cannabis treatments. Their powerful testimonials serve to humanize the concept of medical cannabis, highlighting its potential amidst the ongoing crisis.

📈 With Sweden facing an unfortunate surge in firearm-related violence and drug-related deaths, it's imperative to explore all therapeutic options, including medical cannabis. Emphasizing education over punitive measures could mark the beginning of a new approach in drug policy.

✨ This conference is a critical step toward empowering healthcare professionals with the knowledge they need to prescribe cannabis-based treatments confidently, which could have a transformative impact on numerous lives.

👥 Join us in this educational journey. Celebrate the power of knowledge and be part of a potential turning point in Sweden's approach to its current drug crisis.

Join the pivotal conversation on medical cannabis at the Stockholm Medical Cannabis Conference. Explore diverse topics surrounding the potential benefits of cannabis, patient narratives, and the impact of shifting from punitive to harm reduction strategies. Be part of the solution in Sweden's escala...

28/06/2023

🔬 Just Published! 🔬

Are you captivated by the potential therapeutic applications of topical cannabinoids for various skin conditions and pain management? 🌿 If so, our latest article is a comprehensive resource you shouldn't miss!

In our deep dive into the world of topical cannabinoids 🌍, we illuminate the potential therapeutic benefits of creams, lotions, and balms, drawing insights from a host of scientific studies. From atopic dermatitis to wounds and psoriasis, the article lays bare the intricate relationship between cannabinoids and skin health.

The article is also complemented by a comprehensive table, summarizing numerous research studies on the topical use of cannabinoids for dermatological disorders, their designs, treatment regimens, results, and any adverse events reported. This table serves as a quick yet detailed guide to the current state of knowledge on this topic.

But there's more! We also underscore the critical issues of product quality and cannabinoid content variability, arming consumers with knowledge to make well-informed decisions.

Join us as we explore the dynamic world of topical cannabinoids and how the ongoing research and regulatory advancements are shaping their efficacy, safety, and overall quality.


Give it a read, learn something new, and share your thoughts with us! 👇

Dive into the realm of topical cannabinoids and their applications in treating various skin conditions and managing pain. This in-depth review unravels the scientific evidence, market availability, regulatory status, and future prospects of these potent compounds. Equip yourself with the latest know...

19/06/2023

🌿 Rethinking Medical Cannabis: A New Perspective on the 'High' 🌿

In the world of medicine, the use of has always sparked intense debate. The 'high', or psychoactive effects of THC, are often seen as a to be avoided. But what if we've been looking at it all wrong?

In our latest article, "Cannabis Conundrum: Is the 'High' a Side Effect or a Separate Show?", we delve into a recent study that challenges this prevailing notion. The study suggests that 'feeling high' or 'stoned' may be a separate phenomenon that doesn't interfere with the of and is associated with improved patient outcomes and .

Join us as we explore this fascinating topic, moving beyond the traditional dichotomy of therapeutic effects versus psychoactive side effects. We invite you to reconsider your understanding of the 'high' in medical cannabis use and its role in patient outcomes.

Dive into the world of medical cannabis and the controversial 'high' it induces. This article, grounded in recent research, challenges the notion that the 'high' is an unwanted side effect, suggesting instead that it may be a separate phenomenon that doesn't hinder the therapeutic potential of canna...