25/12/2025
We are pleased to present the article “Sexual Desire Disorder and Major Affective Distress: Implications and Therapeutic Interventions”, authored by Dan Octavian Rusu (Babeș-Bolyai University of Cluj-Napoca) and Cristian Delcea (Sexology Institute of Romania).
DOI: http://dx.doi.org/10.70594/brain/16.2/19
This paper offers an in-depth and clinically relevant exploration of the complex relationship between sexual desire disorder (SDD) and major depressive disorder (MDD), two conditions that frequently coexist and significantly impact emotional well-being, intimate relationships, and overall quality of life. Drawing on a comprehensive review of current scientific literature, the authors examine the psychological, relational, and biological mechanisms that link these conditions.
The study emphasizes the importance of a biopsychosocial perspective, highlighting how emotional vulnerability, family history, relational stressors, and individual coping mechanisms interact in the development and persistence of sexual and affective disorders. Special attention is given to the role of cognitive-behavioural therapy (CBT) and couples therapy, which emerge as effective interventions for improving communication, reducing distress, and restoring relational balance.
By integrating evidence from clinical studies and therapeutic practice, this work underscores the value of personalised and interdisciplinary approaches in mental health care. It also reinforces the importance of early identification, prevention of relapse, and coordinated therapeutic strategies for individuals affected by sexual desire disorders and associated mood disturbances.
Overall, this article provides a thoughtful and clinically grounded contribution to the understanding and treatment of complex affective and relational conditions, offering valuable insights for mental health professionals and researchers alike.