27/11/2021
The new Omicron coronavirus variant - identified first in South Africa, but also detected in Europe and Asia - is raising concern worldwide given the number of mutations, which might help it spread or even evade antibodies from prior infection or vaccination.
News of the variant prompted countries to announce new travel restrictions on Friday and sent drugmakers scrambling to see if their COVID-19 vaccines remain protective.
Why Are Scientists Worried?
The World Health Organization on Friday classified the B.1.1.529 variant, or omicron, as a SARS-CoV-2 "variant of concern," saying it may spread more quickly than other forms of coronavirus.
The delta variant remains dominant worldwide, accounting for 99.9% of U.S. cases, and it is not yet clear whether omicron will be able to displace delta, said Dr. Graham Snyder, medical director, infection prevention and hospital epidemiology at University of Pittsburgh Medical Center.
But the new variant has more than 30 mutations in the part of the virus that current vaccines target. It is also suspected of driving a spike in new infections in South Africa.
Omicron's mutations are likely to render certain COVID-19 treatments - including some manufactured antibodies - ineffective, said Dr. David Ho, professor of microbiology and immunology at Columbia University.
Experimental antiviral pills - such as Pfizer's Paxlovid and Merck & Co’s molnupiravir – target parts of the virus that are not changed in omicron, and these drugs could become even more important if vaccine-induced and natural immunity are threatened.
https://www.voanews.com/a/explainer-how-worried-should-we-be-about-omicron-variant-/6330222.html